NL1003283C2 - Modificatie van een polypeptide voor het vergroten van de elektro- transport-flux en toepassing daarvan als geneesmiddel. - Google Patents
Modificatie van een polypeptide voor het vergroten van de elektro- transport-flux en toepassing daarvan als geneesmiddel. Download PDFInfo
- Publication number
- NL1003283C2 NL1003283C2 NL1003283A NL1003283A NL1003283C2 NL 1003283 C2 NL1003283 C2 NL 1003283C2 NL 1003283 A NL1003283 A NL 1003283A NL 1003283 A NL1003283 A NL 1003283A NL 1003283 C2 NL1003283 C2 NL 1003283C2
- Authority
- NL
- Netherlands
- Prior art keywords
- analog
- polypeptide
- gin
- electrotransport
- ala
- Prior art date
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- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Electrotherapy Devices (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46661095A | 1995-06-06 | 1995-06-06 | |
| US46661095 | 1995-06-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL1003283A1 NL1003283A1 (nl) | 1996-12-09 |
| NL1003283C2 true NL1003283C2 (nl) | 1997-05-02 |
Family
ID=23852435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL1003283A NL1003283C2 (nl) | 1995-06-06 | 1996-06-06 | Modificatie van een polypeptide voor het vergroten van de elektro- transport-flux en toepassing daarvan als geneesmiddel. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7324846B2 (it) |
| JP (2) | JP4354529B2 (it) |
| AU (1) | AU6590396A (it) |
| BE (1) | BE1009704A3 (it) |
| BR (1) | BR9609149A (it) |
| CA (1) | CA2220146A1 (it) |
| DE (1) | DE19681439T1 (it) |
| FR (1) | FR2735132B1 (it) |
| GB (1) | GB2317179B (it) |
| IT (1) | IT1285405B1 (it) |
| NL (1) | NL1003283C2 (it) |
| WO (1) | WO1996039422A2 (it) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1285405B1 (it) * | 1995-06-06 | 1998-06-03 | Alza Corp | Modificazione di farmaci polipeptidici per accrescere il flusso per elettrotrasporto. |
| JP4868678B2 (ja) | 1999-10-14 | 2012-02-01 | ポーラ化成工業株式会社 | エレクトロポーレーション用の組成物 |
| ATE348883T1 (de) * | 2000-09-08 | 2007-01-15 | Massachusetts Inst Technology | Zusammensetzungen und verfahren mit analogen von g-csf |
| WO2004022033A1 (en) * | 2002-09-04 | 2004-03-18 | Microchips, Inc. | Method and device for the controlled delivery of parathyroid hormone |
| CN1688696A (zh) * | 2002-09-18 | 2005-10-26 | 蒙特利尔大学医疗中心 | Ghrh类似物 |
| MX2012010148A (es) | 2010-03-04 | 2013-01-22 | Pfenex Inc | Metodo para producir proteinas de interferon recombinantes solubles sin desnaturalizacion. |
| WO2011123570A2 (en) | 2010-04-01 | 2011-10-06 | Pfenex Inc. | Methods for g-csf production in a pseudomonas host cell |
| CA2857501C (en) | 2011-11-30 | 2020-06-23 | 3M Innovative Properties Company | Microneedle device having a peptide therapeutic agent and an amino acid, methods of making and using the same |
| MX2017013802A (es) | 2015-04-29 | 2018-08-15 | Radius Pharmaceuticals Inc | Métodos para tratar el cáncer. |
| KR102557321B1 (ko) | 2017-01-05 | 2023-07-18 | 래디어스 파마슈티컬스, 인코포레이티드 | Rad1901-2hcl의 다형 형태 |
| EP3817821A1 (en) | 2018-07-04 | 2021-05-12 | Radius Pharmaceuticals, Inc. | Polymorphic forms of rad 1901-2hcl |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4628043A (en) * | 1983-04-26 | 1986-12-09 | The Salk Institute For Biological Studies | Hypothalamic GRF agonists |
| WO1993025197A1 (en) * | 1992-06-12 | 1993-12-23 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
| EP0643981A1 (en) * | 1993-09-22 | 1995-03-22 | Takeda Chemical Industries, Ltd. | A matrix for iontophoreses |
| WO1995011988A1 (en) * | 1993-10-25 | 1995-05-04 | Affymax Technologies N.V. | Compounds with pth activity and recombinant dna vectors encoding same |
| EP0667355A1 (de) * | 1994-02-10 | 1995-08-16 | Hoechst Aktiengesellschaft | Hirudinderivate und Verfahren zu deren Herstellung |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4250878A (en) | 1978-11-22 | 1981-02-17 | Motion Control, Inc. | Non-invasive chemical species delivery apparatus and method |
| US4431739A (en) | 1979-11-05 | 1984-02-14 | Genentech, Inc. | Transformant bacterial culture capable of expressing heterologous protein |
| US4383529A (en) | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
| US4528190A (en) * | 1983-10-25 | 1985-07-09 | The Salk Institute For Biological Studies | GRF Analogs IV |
| US4631211A (en) | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
| US4722726A (en) | 1986-02-12 | 1988-02-02 | Key Pharmaceuticals, Inc. | Method and apparatus for iontophoretic drug delivery |
| US5250022A (en) | 1990-09-25 | 1993-10-05 | Rutgers, The State University Of New Jersey | Iontotherapeutic devices, reservoir electrode devices therefore, process and unit dose |
| AU609769B2 (en) | 1987-02-10 | 1991-05-09 | Drug Delivery Systems Inc. | Electrolytic transdermal delivery of proteins |
| US5013653A (en) | 1987-03-20 | 1991-05-07 | Creative Biomolecules, Inc. | Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage |
| EP0429842B1 (en) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
| GB9107846D0 (en) * | 1990-04-30 | 1991-05-29 | Ici Plc | Polypeptides |
| DK10191D0 (da) | 1991-01-22 | 1991-01-22 | Novo Nordisk As | Hidtil ukendte peptider |
| CA2087087C (en) | 1992-01-22 | 2000-07-18 | Burton H. Sage, Jr. | Molecules for iontophoretic delivery |
| ATE162728T1 (de) * | 1992-12-31 | 1998-02-15 | Alza Corp | Elektrophorese-system mit biegsamen mitteln |
| WO1994028967A1 (fr) * | 1993-06-08 | 1994-12-22 | Hisamitsu Pharmaceutical Co., Inc. | Systeme d'iontophorese |
| IT1285405B1 (it) * | 1995-06-06 | 1998-06-03 | Alza Corp | Modificazione di farmaci polipeptidici per accrescere il flusso per elettrotrasporto. |
-
1996
- 1996-06-05 IT IT96TO000496A patent/IT1285405B1/it active IP Right Grant
- 1996-06-06 FR FR9607002A patent/FR2735132B1/fr not_active Expired - Fee Related
- 1996-06-06 JP JP50171097A patent/JP4354529B2/ja not_active Expired - Fee Related
- 1996-06-06 WO PCT/US1996/009377 patent/WO1996039422A2/en active Application Filing
- 1996-06-06 GB GB9725981A patent/GB2317179B/en not_active Expired - Fee Related
- 1996-06-06 AU AU65903/96A patent/AU6590396A/en not_active Abandoned
- 1996-06-06 DE DE19681439T patent/DE19681439T1/de not_active Withdrawn
- 1996-06-06 NL NL1003283A patent/NL1003283C2/nl not_active IP Right Cessation
- 1996-06-06 BR BR9609149A patent/BR9609149A/pt not_active Application Discontinuation
- 1996-06-06 BE BE9600517A patent/BE1009704A3/fr not_active IP Right Cessation
- 1996-06-06 CA CA002220146A patent/CA2220146A1/en not_active Abandoned
-
2001
- 2001-12-10 US US10/016,403 patent/US7324846B2/en not_active Expired - Fee Related
-
2007
- 2007-11-27 US US11/945,536 patent/US20090275877A1/en not_active Abandoned
-
2008
- 2008-12-12 JP JP2008316824A patent/JP2009149639A/ja not_active Abandoned
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4628043A (en) * | 1983-04-26 | 1986-12-09 | The Salk Institute For Biological Studies | Hypothalamic GRF agonists |
| WO1993025197A1 (en) * | 1992-06-12 | 1993-12-23 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
| EP0643981A1 (en) * | 1993-09-22 | 1995-03-22 | Takeda Chemical Industries, Ltd. | A matrix for iontophoreses |
| WO1995011988A1 (en) * | 1993-10-25 | 1995-05-04 | Affymax Technologies N.V. | Compounds with pth activity and recombinant dna vectors encoding same |
| EP0667355A1 (de) * | 1994-02-10 | 1995-08-16 | Hoechst Aktiengesellschaft | Hirudinderivate und Verfahren zu deren Herstellung |
Also Published As
| Publication number | Publication date |
|---|---|
| IE960413A1 (en) | 1996-12-11 |
| US7324846B2 (en) | 2008-01-29 |
| AU6590396A (en) | 1996-12-24 |
| WO1996039422A2 (en) | 1996-12-12 |
| CA2220146A1 (en) | 1996-12-12 |
| GB2317179A (en) | 1998-03-18 |
| WO1996039422A3 (en) | 1997-03-06 |
| ITTO960496A1 (it) | 1997-12-05 |
| GB9725981D0 (en) | 1998-02-04 |
| DE19681439T1 (de) | 1998-07-23 |
| US20090275877A1 (en) | 2009-11-05 |
| FR2735132A1 (fr) | 1996-12-13 |
| NL1003283A1 (nl) | 1996-12-09 |
| JPH11507341A (ja) | 1999-06-29 |
| ITTO960496A0 (it) | 1996-06-05 |
| JP4354529B2 (ja) | 2009-10-28 |
| IT1285405B1 (it) | 1998-06-03 |
| BE1009704A3 (fr) | 1997-07-01 |
| GB2317179B (en) | 1999-07-28 |
| US20020107505A1 (en) | 2002-08-08 |
| JP2009149639A (ja) | 2009-07-09 |
| FR2735132B1 (fr) | 1998-04-24 |
| BR9609149A (pt) | 1999-02-23 |
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| AD1A | A request for search or an international type search has been filed | ||
| PD2B | A search report has been drawn up | ||
| V1 | Lapsed because of non-payment of the annual fee |
Effective date: 20120101 |