NI200700225A - Purificación de rapamicina - Google Patents
Purificación de rapamicinaInfo
- Publication number
- NI200700225A NI200700225A NI200700225A NI200700225A NI200700225A NI 200700225 A NI200700225 A NI 200700225A NI 200700225 A NI200700225 A NI 200700225A NI 200700225 A NI200700225 A NI 200700225A NI 200700225 A NI200700225 A NI 200700225A
- Authority
- NI
- Nicaragua
- Prior art keywords
- rapamycin
- purification
- purified rapamycin
- chemical method
- obtaining
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describe rapamicina purificada y un procedimiento químico para obtener la rapamicina purificada.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65791005P | 2005-03-02 | 2005-03-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
NI200700225A true NI200700225A (es) | 2008-07-03 |
Family
ID=36568679
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NI200700225A NI200700225A (es) | 2005-03-02 | 2007-08-30 | Purificación de rapamicina |
Country Status (15)
Country | Link |
---|---|
US (1) | US7384953B2 (es) |
EP (1) | EP1853612A1 (es) |
JP (1) | JP2008531686A (es) |
KR (1) | KR20070107087A (es) |
CN (1) | CN101133065A (es) |
AU (1) | AU2006218918A1 (es) |
CA (1) | CA2599582A1 (es) |
CR (1) | CR9297A (es) |
IL (1) | IL185077A0 (es) |
MX (1) | MX2007010716A (es) |
NI (1) | NI200700225A (es) |
NO (1) | NO20074102L (es) |
RU (1) | RU2007130406A (es) |
WO (1) | WO2006093745A1 (es) |
ZA (1) | ZA200707523B (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2493878C (en) | 2002-07-30 | 2013-07-23 | Wyeth | Parenteral formulations containing a rapamycin hydroxyester |
EP2079748A4 (en) * | 2006-11-10 | 2011-05-04 | Biocon Ltd | PURE FORM OF RAPAMYCIN AND ITS RECOVERY AND PURIFICATION PROCESS |
US8425459B2 (en) | 2006-11-20 | 2013-04-23 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent |
US8414910B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US8430055B2 (en) | 2008-08-29 | 2013-04-30 | Lutonix, Inc. | Methods and apparatuses for coating balloon catheters |
US8414525B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US20080276935A1 (en) | 2006-11-20 | 2008-11-13 | Lixiao Wang | Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs |
US8414526B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids |
US8414909B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US9737640B2 (en) | 2006-11-20 | 2017-08-22 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US9700704B2 (en) | 2006-11-20 | 2017-07-11 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
US8998846B2 (en) | 2006-11-20 | 2015-04-07 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
JP2012533548A (ja) | 2009-07-14 | 2012-12-27 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 組成物における黄色形成および過酸化物形成を阻害する方法 |
CN102443012B (zh) * | 2010-10-13 | 2016-03-02 | 鲁南制药集团股份有限公司 | 一种从发酵液中提纯雷帕霉素的方法 |
CN103705925B (zh) | 2012-09-29 | 2018-03-30 | 段磊 | 抑制PI3K/AKT/mTOR信号通路的药物组合 |
US9750728B2 (en) | 2012-09-29 | 2017-09-05 | Targeted Therapeutics, Llc | Method and pharmaceutical composition for inhibiting PI3K/AKT/mTOR signaling pathway |
SG10201707632PA (en) | 2013-03-15 | 2017-11-29 | Biosensors Int Group Ltd | Purification of rapamycin derivatives |
CA2926719C (en) | 2013-10-08 | 2020-11-24 | Lam Therapeutics, Inc. | Rapamycin for the treatment of lymphangioleiomyomatosis |
EP4218742A1 (en) * | 2014-04-04 | 2023-08-02 | AI Therapeutics, Inc. | An inhalable rapamycin formulation for treating age-related conditions |
EP3209330B1 (en) | 2014-10-07 | 2022-02-23 | AI Therapeutics, Inc. | An inhalable sirolimus formulation for the treatment of pulmonary hypertension |
WO2016130645A1 (en) | 2015-02-10 | 2016-08-18 | Lam Therapeutics, Inc. | Rapamycin for the treatment of lymphangioleiomyomatosis |
WO2018031789A1 (en) | 2016-08-10 | 2018-02-15 | The Board Of Regents Of The University Of Texas System | Topical rapamycin therapy |
CN109369679A (zh) * | 2018-12-24 | 2019-02-22 | 江苏卓和药业有限公司 | 一种雷帕霉素的精制方法 |
CN109369680A (zh) * | 2018-12-24 | 2019-02-22 | 江苏卓和药业有限公司 | 一种依维莫司的纯化方法 |
CN109485657A (zh) * | 2018-12-24 | 2019-03-19 | 江苏卓和药业有限公司 | 一种替西罗莫司的纯化方法 |
TW202045165A (zh) | 2019-02-20 | 2020-12-16 | 美商Ai治療公司 | 局部雷帕黴素調配物以及其於治療臉部血管纖維瘤和其他皮膚疾病中的用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3993749A (en) * | 1974-04-12 | 1976-11-23 | Ayerst Mckenna And Harrison Ltd. | Rapamycin and process of preparation |
US5362718A (en) | 1994-04-18 | 1994-11-08 | American Home Products Corporation | Rapamycin hydroxyesters |
US6277983B1 (en) | 2000-09-27 | 2001-08-21 | American Home Products Corporation | Regioselective synthesis of rapamycin derivatives |
WO2005010010A1 (en) | 2003-07-16 | 2005-02-03 | Wyeth | Cci-779 isomer c |
KR20060057605A (ko) | 2003-08-07 | 2006-05-26 | 와이어쓰 | Cci-779의 위치선택적 합성 방법 |
-
2006
- 2006-02-22 CA CA002599582A patent/CA2599582A1/en not_active Abandoned
- 2006-02-22 US US11/359,294 patent/US7384953B2/en not_active Expired - Fee Related
- 2006-02-22 MX MX2007010716A patent/MX2007010716A/es active IP Right Grant
- 2006-02-22 CN CNA2006800066093A patent/CN101133065A/zh active Pending
- 2006-02-22 WO PCT/US2006/006212 patent/WO2006093745A1/en active Application Filing
- 2006-02-22 KR KR1020077019849A patent/KR20070107087A/ko not_active Application Discontinuation
- 2006-02-22 AU AU2006218918A patent/AU2006218918A1/en not_active Abandoned
- 2006-02-22 JP JP2007558062A patent/JP2008531686A/ja active Pending
- 2006-02-22 EP EP06735746A patent/EP1853612A1/en not_active Withdrawn
- 2006-02-22 RU RU2007130406/04A patent/RU2007130406A/ru unknown
-
2007
- 2007-08-06 IL IL185077A patent/IL185077A0/en unknown
- 2007-08-08 CR CR9297A patent/CR9297A/es not_active Application Discontinuation
- 2007-08-08 NO NO20074102A patent/NO20074102L/no not_active Application Discontinuation
- 2007-08-30 NI NI200700225A patent/NI200700225A/es unknown
- 2007-08-31 ZA ZA200707523A patent/ZA200707523B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
MX2007010716A (es) | 2008-01-16 |
JP2008531686A (ja) | 2008-08-14 |
EP1853612A1 (en) | 2007-11-14 |
CA2599582A1 (en) | 2006-09-08 |
AU2006218918A1 (en) | 2006-09-08 |
KR20070107087A (ko) | 2007-11-06 |
CN101133065A (zh) | 2008-02-27 |
US7384953B2 (en) | 2008-06-10 |
NO20074102L (no) | 2007-09-26 |
US20060199954A1 (en) | 2006-09-07 |
ZA200707523B (en) | 2010-02-24 |
WO2006093745A1 (en) | 2006-09-08 |
CR9297A (es) | 2008-01-21 |
RU2007130406A (ru) | 2009-04-10 |
IL185077A0 (en) | 2007-12-03 |
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