MY182382A - Imidazopyrazinones as pde1 inhibitors - Google Patents

Imidazopyrazinones as pde1 inhibitors

Info

Publication number
MY182382A
MY182382A MYPI2017001597A MYPI2017001597A MY182382A MY 182382 A MY182382 A MY 182382A MY PI2017001597 A MYPI2017001597 A MY PI2017001597A MY PI2017001597 A MYPI2017001597 A MY PI2017001597A MY 182382 A MY182382 A MY 182382A
Authority
MY
Malaysia
Prior art keywords
imidazopyrazinones
pde1 inhibitors
pde1
inhibitors
medicament
Prior art date
Application number
MYPI2017001597A
Other languages
English (en)
Inventor
Jan Kehler
Morten Langgard
Karsten Juhl
Lars Kyhn Rasmussen
Mikkel Jessing
Paulo Jorge Vieira Vital
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of MY182382A publication Critical patent/MY182382A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MYPI2017001597A 2015-04-30 2016-04-29 Imidazopyrazinones as pde1 inhibitors MY182382A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA201500261 2015-04-30
DKPA201500666 2015-10-29
DKPA201600202 2016-04-04
PCT/EP2016/059583 WO2016174188A1 (en) 2015-04-30 2016-04-29 Imidazopyrazinones as pde1 inhibitors

Publications (1)

Publication Number Publication Date
MY182382A true MY182382A (en) 2021-01-22

Family

ID=55910242

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2017001597A MY182382A (en) 2015-04-30 2016-04-29 Imidazopyrazinones as pde1 inhibitors

Country Status (42)

Country Link
US (4) US20160318939A1 (OSRAM)
EP (1) EP3288944B1 (OSRAM)
JP (1) JP6663930B2 (OSRAM)
KR (1) KR102605759B1 (OSRAM)
CN (1) CN107531714B (OSRAM)
AU (1) AU2016256573B2 (OSRAM)
BR (1) BR112017023182B1 (OSRAM)
CA (1) CA2983563A1 (OSRAM)
CL (1) CL2017002719A1 (OSRAM)
CO (1) CO2017010399A2 (OSRAM)
CY (1) CY1121806T1 (OSRAM)
DK (1) DK3288944T3 (OSRAM)
DO (1) DOP2017000254A (OSRAM)
EA (1) EA031946B1 (OSRAM)
EC (1) ECSP17072228A (OSRAM)
ES (1) ES2735422T3 (OSRAM)
GE (1) GEP20207058B (OSRAM)
GT (1) GT201700223A (OSRAM)
HK (1) HK1252098B (OSRAM)
HR (1) HRP20191180T1 (OSRAM)
HU (1) HUE044244T2 (OSRAM)
IL (1) IL255316B (OSRAM)
JO (1) JO3627B1 (OSRAM)
LT (1) LT3288944T (OSRAM)
MA (1) MA41977B1 (OSRAM)
ME (1) ME03414B (OSRAM)
MX (1) MX375737B (OSRAM)
MY (1) MY182382A (OSRAM)
PE (1) PE20180121A1 (OSRAM)
PH (1) PH12017501990B1 (OSRAM)
PL (1) PL3288944T3 (OSRAM)
PT (1) PT3288944T (OSRAM)
RS (1) RS59051B1 (OSRAM)
RU (1) RU2712219C2 (OSRAM)
SG (1) SG11201708822PA (OSRAM)
SI (1) SI3288944T1 (OSRAM)
SM (1) SMT201900393T1 (OSRAM)
TN (1) TN2017000428A1 (OSRAM)
TW (1) TWI695838B (OSRAM)
UA (1) UA123050C2 (OSRAM)
WO (1) WO2016174188A1 (OSRAM)
ZA (1) ZA201706847B (OSRAM)

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TW201629064A (zh) 2014-10-10 2016-08-16 H 朗德貝克公司 作爲pde1抑制劑之三唑並吡酮
JO3627B1 (ar) 2015-04-30 2020-08-27 H Lundbeck As إيميدازو بيرازينونات على هيئة مثبطات pde1
TWI729109B (zh) 2016-04-12 2021-06-01 丹麥商H 朗德貝克公司 作爲PDE1抑制劑的1,5-二氫-4H-吡唑并[3,4-d]嘧啶-4-酮和1,5-二氫-4H-吡唑并[4,3-c]吡啶-4-酮
EP3529250B1 (en) 2016-10-18 2023-12-06 H. Lundbeck A/S Imidazopyrazinones, pyrazolopyrimidinones and pyrazolopyridinones as pde1 inhibitors
MA46621A (fr) 2016-10-28 2021-06-02 H Lundbeck As Traitements combinés comprenant l'administration d'imidazopyrazinones
PT3532064T (pt) * 2016-10-28 2020-09-03 H Lundbeck As Tratamentos de combinação compreendendo imidazopirazinonas para o tratamento de distúrbios psiquiátricos e/ou cognitivos
JOP20190126A1 (ar) 2016-12-22 2019-05-28 H Lundbeck As بيرازولو [3، 4-b] بيريدينات وإيميدازو [1، 5-b] بيريدازينات على هيئة مثبطات PDE1
WO2018125810A1 (en) 2016-12-28 2018-07-05 Dart Neuroscience, Llc Substituted pyrazolopyrimidinone compounds as pde2 inhibitors
CN111655695B (zh) 2017-11-27 2025-05-27 达特神经科学有限公司 作为pde1抑制剂的取代的呋喃并嘧啶化合物
AR113926A1 (es) * 2017-12-14 2020-07-01 H Lundbeck As Derivados de 1h-pirazolo[4,3-b]piridinas
WO2019121840A1 (en) 2017-12-20 2019-06-27 H. Lundbeck A/S Pyrazolo[3,4-b]pyridines and imidazo[1,5-b]pyridazines as pde1 inhibitors
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WO2020210614A1 (en) 2019-04-12 2020-10-15 Intra-Cellular Therapies, Inc. Organic compounds
IT202200024948A1 (it) * 2022-12-05 2024-06-05 Angelini Pharma S P A Composti attivatori dei canali potassio KV7.2/KV7.3

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JO3627B1 (ar) 2015-04-30 2020-08-27 H Lundbeck As إيميدازو بيرازينونات على هيئة مثبطات pde1
JO3711B1 (ar) 2015-07-13 2021-01-31 H Lundbeck As أجسام مضادة محددة لبروتين تاو وطرق استعمالها
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EP3529250B1 (en) 2016-10-18 2023-12-06 H. Lundbeck A/S Imidazopyrazinones, pyrazolopyrimidinones and pyrazolopyridinones as pde1 inhibitors
MA46621A (fr) 2016-10-28 2021-06-02 H Lundbeck As Traitements combinés comprenant l'administration d'imidazopyrazinones
PT3532064T (pt) 2016-10-28 2020-09-03 H Lundbeck As Tratamentos de combinação compreendendo imidazopirazinonas para o tratamento de distúrbios psiquiátricos e/ou cognitivos

Also Published As

Publication number Publication date
JO3627B1 (ar) 2020-08-27
US20170291903A1 (en) 2017-10-12
UA123050C2 (uk) 2021-02-10
DOP2017000254A (es) 2018-01-15
LT3288944T (lt) 2019-07-25
PT3288944T (pt) 2019-07-19
US10011606B2 (en) 2018-07-03
ES2735422T3 (es) 2019-12-18
PL3288944T3 (pl) 2019-11-29
CL2017002719A1 (es) 2018-04-20
US11472810B2 (en) 2022-10-18
KR20170140216A (ko) 2017-12-20
GEP20207058B (en) 2020-01-27
DK3288944T3 (da) 2019-07-22
JP2018514552A (ja) 2018-06-07
US20160318939A1 (en) 2016-11-03
MX2017013785A (es) 2018-03-27
TW201700477A (zh) 2017-01-01
HRP20191180T1 (hr) 2019-10-04
SG11201708822PA (en) 2017-11-29
PH12017501990B1 (en) 2021-01-13
MA41977B1 (fr) 2019-08-30
US20210238182A1 (en) 2021-08-05
BR112017023182B1 (pt) 2023-10-31
CN107531714B (zh) 2019-07-19
EP3288944B1 (en) 2019-06-12
EA031946B1 (ru) 2019-03-29
BR112017023182A2 (OSRAM) 2018-10-02
IL255316A0 (en) 2017-12-31
US20190062335A1 (en) 2019-02-28
EA201792157A1 (ru) 2018-03-30
US10858362B2 (en) 2020-12-08
AU2016256573B2 (en) 2019-11-21
PH12017501990A1 (en) 2018-03-26
HK1252098B (en) 2020-02-07
CY1121806T1 (el) 2020-07-31
HUE044244T2 (hu) 2019-10-28
CO2017010399A2 (es) 2018-01-05
RS59051B1 (sr) 2019-08-30
SMT201900393T1 (it) 2019-09-09
MA41977A (fr) 2018-07-23
MX375737B (es) 2025-03-06
PE20180121A1 (es) 2018-01-18
CN107531714A (zh) 2018-01-02
ME03414B (me) 2020-01-20
SI3288944T1 (sl) 2019-08-30
EP3288944A1 (en) 2018-03-07
TN2017000428A1 (en) 2019-04-12
HK1252098A1 (en) 2019-05-17
GT201700223A (es) 2018-12-19
CA2983563A1 (en) 2016-11-03
AU2016256573A1 (en) 2017-12-14
WO2016174188A1 (en) 2016-11-03
JP6663930B2 (ja) 2020-03-13
ECSP17072228A (es) 2018-02-28
RU2712219C2 (ru) 2020-01-27
TWI695838B (zh) 2020-06-11
RU2017137514A3 (OSRAM) 2019-07-17
KR102605759B1 (ko) 2023-11-23
RU2017137514A (ru) 2019-05-31
IL255316B (en) 2021-10-31
ZA201706847B (en) 2019-01-30

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