GT201700223A - Imidazopirazinonas como inhibidores de pde 1 - Google Patents

Imidazopirazinonas como inhibidores de pde 1

Info

Publication number
GT201700223A
GT201700223A GT201700223A GT201700223A GT201700223A GT 201700223 A GT201700223 A GT 201700223A GT 201700223 A GT201700223 A GT 201700223A GT 201700223 A GT201700223 A GT 201700223A GT 201700223 A GT201700223 A GT 201700223A
Authority
GT
Guatemala
Prior art keywords
imidazopirazinonas
pde inhibitors
inhibitors
imidazopirazinones
pde1
Prior art date
Application number
GT201700223A
Other languages
English (en)
Spanish (es)
Inventor
Jan Kehler
Lars Kyhn Rasmussen
Morten Langgård
Mikkel Jessing
Paulo Jorge Vieira Vital
Karsten Juhl
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of GT201700223A publication Critical patent/GT201700223A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GT201700223A 2015-04-30 2017-10-24 Imidazopirazinonas como inhibidores de pde 1 GT201700223A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201500261 2015-04-30
DKPA201500666 2015-10-29
DKPA201600202 2016-04-04

Publications (1)

Publication Number Publication Date
GT201700223A true GT201700223A (es) 2018-12-19

Family

ID=55910242

Family Applications (1)

Application Number Title Priority Date Filing Date
GT201700223A GT201700223A (es) 2015-04-30 2017-10-24 Imidazopirazinonas como inhibidores de pde 1

Country Status (42)

Country Link
US (4) US20160318939A1 (OSRAM)
EP (1) EP3288944B1 (OSRAM)
JP (1) JP6663930B2 (OSRAM)
KR (1) KR102605759B1 (OSRAM)
CN (1) CN107531714B (OSRAM)
AU (1) AU2016256573B2 (OSRAM)
BR (1) BR112017023182B1 (OSRAM)
CA (1) CA2983563A1 (OSRAM)
CL (1) CL2017002719A1 (OSRAM)
CO (1) CO2017010399A2 (OSRAM)
CY (1) CY1121806T1 (OSRAM)
DK (1) DK3288944T3 (OSRAM)
DO (1) DOP2017000254A (OSRAM)
EA (1) EA031946B1 (OSRAM)
EC (1) ECSP17072228A (OSRAM)
ES (1) ES2735422T3 (OSRAM)
GE (1) GEP20207058B (OSRAM)
GT (1) GT201700223A (OSRAM)
HK (1) HK1252098B (OSRAM)
HR (1) HRP20191180T1 (OSRAM)
HU (1) HUE044244T2 (OSRAM)
IL (1) IL255316B (OSRAM)
JO (1) JO3627B1 (OSRAM)
LT (1) LT3288944T (OSRAM)
MA (1) MA41977B1 (OSRAM)
ME (1) ME03414B (OSRAM)
MX (1) MX375737B (OSRAM)
MY (1) MY182382A (OSRAM)
PE (1) PE20180121A1 (OSRAM)
PH (1) PH12017501990B1 (OSRAM)
PL (1) PL3288944T3 (OSRAM)
PT (1) PT3288944T (OSRAM)
RS (1) RS59051B1 (OSRAM)
RU (1) RU2712219C2 (OSRAM)
SG (1) SG11201708822PA (OSRAM)
SI (1) SI3288944T1 (OSRAM)
SM (1) SMT201900393T1 (OSRAM)
TN (1) TN2017000428A1 (OSRAM)
TW (1) TWI695838B (OSRAM)
UA (1) UA123050C2 (OSRAM)
WO (1) WO2016174188A1 (OSRAM)
ZA (1) ZA201706847B (OSRAM)

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JO3627B1 (ar) 2015-04-30 2020-08-27 H Lundbeck As إيميدازو بيرازينونات على هيئة مثبطات pde1
TWI729109B (zh) 2016-04-12 2021-06-01 丹麥商H 朗德貝克公司 作爲PDE1抑制劑的1,5-二氫-4H-吡唑并[3,4-d]嘧啶-4-酮和1,5-二氫-4H-吡唑并[4,3-c]吡啶-4-酮
WO2018073251A1 (en) 2016-10-18 2018-04-26 H. Lundbeck A/S Imidazopyrazinones, pyrazolopyrimidinones and pyrazolopyridinones as pde1 inhibitors
EP3532053A1 (en) 2016-10-28 2019-09-04 H. Lundbeck A/S Combination treatments comprising administration of imidazopyrazinones
DK3532064T3 (da) * 2016-10-28 2020-08-24 H Lundbeck As Kombinationsbehandlinger omfattende imidazopyrazinoner til behandlingen af psykiatriske og/eller kognitive lidelser
JOP20190126A1 (ar) 2016-12-22 2019-05-28 H Lundbeck As بيرازولو [3، 4-b] بيريدينات وإيميدازو [1، 5-b] بيريدازينات على هيئة مثبطات PDE1
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AR113926A1 (es) * 2017-12-14 2020-07-01 H Lundbeck As Derivados de 1h-pirazolo[4,3-b]piridinas
CN111511742B (zh) 2017-12-20 2023-10-27 H.隆德贝克有限公司 作为PDE1抑制剂的吡唑并[4,3-b]吡啶和咪唑并[1,5-a]嘧啶
KR20210013214A (ko) 2018-05-25 2021-02-03 인트라-셀룰라 써래피스, 인코퍼레이티드. 유기 화합물
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EP3532053A1 (en) 2016-10-28 2019-09-04 H. Lundbeck A/S Combination treatments comprising administration of imidazopyrazinones

Also Published As

Publication number Publication date
WO2016174188A1 (en) 2016-11-03
EA201792157A1 (ru) 2018-03-30
UA123050C2 (uk) 2021-02-10
ECSP17072228A (es) 2018-02-28
DOP2017000254A (es) 2018-01-15
SG11201708822PA (en) 2017-11-29
CO2017010399A2 (es) 2018-01-05
ME03414B (me) 2020-01-20
TW201700477A (zh) 2017-01-01
MA41977A (fr) 2018-07-23
CN107531714A (zh) 2018-01-02
JP2018514552A (ja) 2018-06-07
AU2016256573A1 (en) 2017-12-14
HK1252098B (en) 2020-02-07
HUE044244T2 (hu) 2019-10-28
PH12017501990B1 (en) 2021-01-13
KR20170140216A (ko) 2017-12-20
EA031946B1 (ru) 2019-03-29
EP3288944A1 (en) 2018-03-07
BR112017023182B1 (pt) 2023-10-31
CA2983563A1 (en) 2016-11-03
SMT201900393T1 (it) 2019-09-09
US20210238182A1 (en) 2021-08-05
US20190062335A1 (en) 2019-02-28
TWI695838B (zh) 2020-06-11
DK3288944T3 (da) 2019-07-22
MX375737B (es) 2025-03-06
PE20180121A1 (es) 2018-01-18
US11472810B2 (en) 2022-10-18
LT3288944T (lt) 2019-07-25
BR112017023182A2 (OSRAM) 2018-10-02
JP6663930B2 (ja) 2020-03-13
AU2016256573B2 (en) 2019-11-21
RS59051B1 (sr) 2019-08-30
MX2017013785A (es) 2018-03-27
US10011606B2 (en) 2018-07-03
PT3288944T (pt) 2019-07-19
HK1252098A1 (en) 2019-05-17
US20170291903A1 (en) 2017-10-12
IL255316B (en) 2021-10-31
MY182382A (en) 2021-01-22
US20160318939A1 (en) 2016-11-03
MA41977B1 (fr) 2019-08-30
EP3288944B1 (en) 2019-06-12
PH12017501990A1 (en) 2018-03-26
CL2017002719A1 (es) 2018-04-20
TN2017000428A1 (en) 2019-04-12
RU2017137514A3 (OSRAM) 2019-07-17
ES2735422T3 (es) 2019-12-18
US10858362B2 (en) 2020-12-08
CN107531714B (zh) 2019-07-19
HRP20191180T1 (hr) 2019-10-04
JO3627B1 (ar) 2020-08-27
RU2712219C2 (ru) 2020-01-27
RU2017137514A (ru) 2019-05-31
KR102605759B1 (ko) 2023-11-23
IL255316A0 (en) 2017-12-31
GEP20207058B (en) 2020-01-27
ZA201706847B (en) 2019-01-30
SI3288944T1 (sl) 2019-08-30
PL3288944T3 (pl) 2019-11-29
CY1121806T1 (el) 2020-07-31

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