MY136769A - Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them - Google Patents

Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them

Info

Publication number
MY136769A
MY136769A MYPI20042944A MYPI20042944A MY136769A MY 136769 A MY136769 A MY 136769A MY PI20042944 A MYPI20042944 A MY PI20042944A MY PI20042944 A MYPI20042944 A MY PI20042944A MY 136769 A MY136769 A MY 136769A
Authority
MY
Malaysia
Prior art keywords
heparin
pharmaceutical compositions
compositions containing
preparation
mixtures derived
Prior art date
Application number
MYPI20042944A
Other languages
English (en)
Inventor
Laux Volker
Mourier Pierre
Viskov Christian
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of MY136769A publication Critical patent/MY136769A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MYPI20042944A 2003-07-24 2004-07-22 Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them MY136769A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0309041A FR2857971B1 (fr) 2003-07-24 2003-07-24 Melanges d'oligosaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
MY136769A true MY136769A (en) 2008-11-28

Family

ID=33561051

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20042944A MY136769A (en) 2003-07-24 2004-07-22 Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them

Country Status (39)

Country Link
EP (1) EP1651677B1 (enrdf_load_stackoverflow)
JP (1) JP4865552B2 (enrdf_load_stackoverflow)
KR (1) KR101125517B1 (enrdf_load_stackoverflow)
CN (1) CN1852926B (enrdf_load_stackoverflow)
AR (1) AR045917A1 (enrdf_load_stackoverflow)
AT (1) ATE487741T1 (enrdf_load_stackoverflow)
AU (1) AU2004259111B2 (enrdf_load_stackoverflow)
BR (1) BRPI0412850A (enrdf_load_stackoverflow)
CA (1) CA2533555A1 (enrdf_load_stackoverflow)
CR (1) CR8201A (enrdf_load_stackoverflow)
CY (1) CY1111165T1 (enrdf_load_stackoverflow)
DE (1) DE602004030015D1 (enrdf_load_stackoverflow)
DK (1) DK1651677T3 (enrdf_load_stackoverflow)
EC (1) ECSP066305A (enrdf_load_stackoverflow)
ES (1) ES2355827T3 (enrdf_load_stackoverflow)
FR (1) FR2857971B1 (enrdf_load_stackoverflow)
GT (1) GT200400145A (enrdf_load_stackoverflow)
HN (1) HN2004000250A (enrdf_load_stackoverflow)
IL (1) IL173206A (enrdf_load_stackoverflow)
MA (1) MA27928A1 (enrdf_load_stackoverflow)
ME (1) MEP11608A (enrdf_load_stackoverflow)
MX (1) MXPA06000336A (enrdf_load_stackoverflow)
MY (1) MY136769A (enrdf_load_stackoverflow)
NO (1) NO20060821L (enrdf_load_stackoverflow)
NZ (1) NZ544717A (enrdf_load_stackoverflow)
OA (1) OA13197A (enrdf_load_stackoverflow)
PA (1) PA8606801A1 (enrdf_load_stackoverflow)
PE (1) PE20050246A1 (enrdf_load_stackoverflow)
PL (1) PL1651677T3 (enrdf_load_stackoverflow)
PT (1) PT1651677E (enrdf_load_stackoverflow)
RS (1) RS20060044A (enrdf_load_stackoverflow)
RU (1) RU2346005C2 (enrdf_load_stackoverflow)
SI (1) SI1651677T1 (enrdf_load_stackoverflow)
TN (1) TNSN06025A1 (enrdf_load_stackoverflow)
TW (1) TWI369208B (enrdf_load_stackoverflow)
UA (1) UA89356C2 (enrdf_load_stackoverflow)
UY (1) UY28435A1 (enrdf_load_stackoverflow)
WO (1) WO2005010051A2 (enrdf_load_stackoverflow)
ZA (1) ZA200600657B (enrdf_load_stackoverflow)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7589145B2 (en) 2004-04-15 2009-09-15 Exxonmobil Chemical Patents Inc. Syndiotactic rich polyolefins
JP2009538386A (ja) * 2006-05-25 2009-11-05 モメンタ ファーマシューティカルズ インコーポレイテッド 低分子量ヘパリン組成物およびその使用
CN101711771B (zh) * 2008-10-07 2015-12-09 上海喜恩医药科技发展有限公司 一种肝素衍生的多糖混合物及其制法和药物组合物
CA2811186C (en) * 2010-09-14 2018-12-04 Michio Muguruma High purity heparin and production method therefor
WO2012072799A1 (en) 2010-12-02 2012-06-07 Aventis Pharma S.A. New methods for the in vitro measurement of the biological activity of an ultra low molecular weight heparin sample
CN102558392A (zh) * 2010-12-14 2012-07-11 王芃 一种高抗FXa、低抗FIIa低分子肝素钠的制备方法
CN102816255B (zh) * 2011-06-10 2015-11-25 王芃 一种超低分子肝素钠的制备方法
US9896517B2 (en) 2013-03-26 2018-02-20 Jiuzhitang Co., Ltd. Low molecular weight glycosaminoglycan derivative, pharmaceutical composition thereof, preparation method therefor and use thereof
CN103864959A (zh) * 2014-04-03 2014-06-18 中国药科大学 一种肝素十二糖抗动脉粥样硬化的用途
RU2639574C2 (ru) * 2016-05-23 2017-12-21 Алексей Георгиевич Александров Способ получения низкомолекулярного гепарина

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
FR2504928A1 (fr) * 1981-04-29 1982-11-05 Choay Sa Oligosaccharides a chaines courtes possedant des proprietes biologiques, leur preparation et leurs applications en tant que medicaments
FR2669932B1 (fr) * 1990-12-03 1994-07-01 Sanofi Sa Nouvel heparosane-n,o-sulfate, son procede de preparation et les compositions pharmaceutiques qui le contiennent.
IT1284143B1 (it) * 1996-09-06 1998-05-08 Istituto Scient Di Chimica E B Eparansolfati semi-sintetici ad elevata attivita' antimetastica e ridotto rischio emorragico
US6075013A (en) * 1997-06-06 2000-06-13 Hamilton Civic Hospitals Research Development Inc. Modified low molecular weight heparin that inhibits clot associated coagulation factors
ES2161615B1 (es) * 1999-07-23 2003-03-16 Rovi Lab Farmaceut Sa Composiciones de heparinas de muy bajo peso molecular.
JP4897991B2 (ja) * 1999-07-23 2012-03-14 ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ 超低分子量ヘパリン組成物
FR2800074B1 (fr) * 1999-10-22 2001-12-21 Aventis Pharma Sa Nouveaux oligosaccharides, leur preparation et les compositions pharmaceutiques les contenant
JP4585072B2 (ja) * 2000-02-29 2010-11-24 扶桑薬品工業株式会社 ヘパリン解重合法、解重合ヘパリン、その誘導体および医薬組成物
FR2807043B1 (fr) * 2000-03-28 2002-11-22 Aventis Pharma Sa Composition pharmaceutique contenant des oligosaccharides, les nouveaux oligosaccharides et leur preparation
FR2811992B1 (fr) * 2000-07-21 2003-07-04 Aventis Pharma Sa Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant
US6969705B2 (en) * 2000-07-21 2005-11-29 Aventis Pharma S.A. Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
JP2005505537A (ja) * 2001-08-28 2005-02-24 レオ・ファーマ・アクティーゼルスカブ 低分子量ヘパリンと低分子量デルマタン硫酸とを含む抗血栓組成物
FR2845686B1 (fr) * 2002-10-10 2013-08-30 Aventis Pharma Sa Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
TNSN06025A1 (en) 2007-10-03
ATE487741T1 (de) 2010-11-15
AU2004259111B2 (en) 2009-06-11
UY28435A1 (es) 2005-02-28
UA89356C2 (ru) 2010-01-25
ES2355827T3 (es) 2011-03-31
HN2004000250A (es) 2006-06-29
MA27928A1 (fr) 2006-06-01
CN1852926B (zh) 2010-05-12
JP2006528614A (ja) 2006-12-21
GT200400145A (es) 2005-03-16
EP1651677A2 (fr) 2006-05-03
AU2004259111A1 (en) 2005-02-03
SI1651677T1 (sl) 2011-03-31
CY1111165T1 (el) 2015-06-11
RU2006105384A (ru) 2007-09-10
AR045917A1 (es) 2005-11-16
RU2346005C2 (ru) 2009-02-10
MEP11608A (en) 2010-06-10
HK1094806A1 (zh) 2007-04-13
DK1651677T3 (da) 2011-02-28
FR2857971A1 (fr) 2005-01-28
OA13197A (fr) 2006-12-13
NO20060821L (no) 2006-04-20
PE20050246A1 (es) 2005-06-02
CN1852926A (zh) 2006-10-25
FR2857971B1 (fr) 2005-08-26
RS20060044A (sr) 2008-06-05
CR8201A (es) 2006-09-22
TWI369208B (en) 2012-08-01
KR101125517B1 (ko) 2012-03-23
NZ544717A (en) 2009-09-25
WO2005010051A2 (fr) 2005-02-03
PT1651677E (pt) 2011-02-08
PL1651677T3 (pl) 2011-04-29
EP1651677B1 (fr) 2010-11-10
IL173206A (en) 2010-11-30
JP4865552B2 (ja) 2012-02-01
ECSP066305A (es) 2006-07-28
ZA200600657B (en) 2007-05-30
CA2533555A1 (fr) 2005-02-03
KR20060059974A (ko) 2006-06-02
BRPI0412850A (pt) 2006-10-03
MXPA06000336A (es) 2006-03-30
PA8606801A1 (es) 2005-02-04
WO2005010051A3 (fr) 2005-06-16
DE602004030015D1 (de) 2010-12-23
TW200522970A (en) 2005-07-16
IL173206A0 (en) 2006-06-11

Similar Documents

Publication Publication Date Title
MY142376A (en) Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
CY1111165T1 (el) Μειγματα ολιγοσακχαριτων που προερχονται απο την ηπαρινη, η παρασκευη τους και οι φαρμακευτικες ενωσεις που τα περιεχουν
WO2002023190A8 (en) Methods and products related to low molecular weight heparin
MXPA05010682A (es) Compuestos novedosos.
BRPI0413241A (pt) composições de adoçante de mesa de monatina e métodos de fazer as mesmas
SG148997A1 (en) Powders comprising low molecular dextran and methods of producing those powders
TW200519075A (en) Novel compounds
MY140840A (en) Acylated, heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals
IL150257A0 (en) Galactomaninan oligosaccharides, pharmaceutical compositions containing the same and methods for the production thereof
IL149154A0 (en) Novel oligosaccharides, preparation method and pharmaceutical compositions containing same
UA92603C2 (ru) Фармацевтическая композиция для лечения тромбоза
GB0216002D0 (en) Process and composition
BRPI0413346A (pt) derivados de polissacarìdeos com alta atividade antitrombótica no plasma
MXPA05012679A (es) Nuevos derivados de imidazoles, su preparacion y su uso como medicamento.
NO20030073D0 (no) Legemiddelleveringssystem for legemidler som er lite vannopplöselige
IL165808A0 (en) Low molecular weight k5-n,o-oversulfated polysaccharide process for the preparation thereof and pharmaceutical compositions containing the same
PL351483A1 (en) Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction
SI1699468T1 (sl) Farmacevtski sestavek, ki obsega kompleks cink-hialuronan, za zdravljenje multiple skleroze
PL1615656T3 (pl) Produkt immunomodulatorowy otrzymany z hodowli bifidobacterium i zawierające go kompozycje
MXPA05011591A (es) Composicion farmaceutica como forma de dosificacion solida y metodo para la elaboracion de la misma.
ATE552004T1 (de) Oral verabreichbare heparinderivate
ATE410173T1 (de) Produkt pflanzlichen ursprungs, das proanthocyane enthält, sowie verfahren zu seiner herstellung
AU2001274138A1 (en) Propanolaminotetralines, preparation thereof and compositions containing same
IL171981A (en) Glycosaminoglycans for treatment of emotional dysfunctions
TH68733A (th) ของผสมของพอลิแซคคาไรด์ที่มาจากเฮพาริน การเตรียมและสารผสมทางเภสัชกรรมที่มีของผสมนั้น