DE602004030015D1 - Mischungen aus von heparin abgeleiteten oligosacchariden, herstellung davon und pharmazeutische zusammensetzungen, die die mischungen enthalten - Google Patents
Mischungen aus von heparin abgeleiteten oligosacchariden, herstellung davon und pharmazeutische zusammensetzungen, die die mischungen enthaltenInfo
- Publication number
- DE602004030015D1 DE602004030015D1 DE602004030015T DE602004030015T DE602004030015D1 DE 602004030015 D1 DE602004030015 D1 DE 602004030015D1 DE 602004030015 T DE602004030015 T DE 602004030015T DE 602004030015 T DE602004030015 T DE 602004030015T DE 602004030015 D1 DE602004030015 D1 DE 602004030015D1
- Authority
- DE
- Germany
- Prior art keywords
- mixtures
- manufacture
- pharmaceutical compositions
- compositions containing
- derived oligosaccharides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0309041A FR2857971B1 (fr) | 2003-07-24 | 2003-07-24 | Melanges d'oligosaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant |
PCT/FR2004/001943 WO2005010051A2 (fr) | 2003-07-24 | 2004-07-22 | Melanges d'oligosaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004030015D1 true DE602004030015D1 (de) | 2010-12-23 |
Family
ID=33561051
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004030015T Active DE602004030015D1 (de) | 2003-07-24 | 2004-07-22 | Mischungen aus von heparin abgeleiteten oligosacchariden, herstellung davon und pharmazeutische zusammensetzungen, die die mischungen enthalten |
Country Status (40)
Country | Link |
---|---|
EP (1) | EP1651677B1 (de) |
JP (1) | JP4865552B2 (de) |
KR (1) | KR101125517B1 (de) |
CN (1) | CN1852926B (de) |
AR (1) | AR045917A1 (de) |
AT (1) | ATE487741T1 (de) |
AU (1) | AU2004259111B2 (de) |
BR (1) | BRPI0412850A (de) |
CA (1) | CA2533555A1 (de) |
CR (1) | CR8201A (de) |
CY (1) | CY1111165T1 (de) |
DE (1) | DE602004030015D1 (de) |
DK (1) | DK1651677T3 (de) |
EC (1) | ECSP066305A (de) |
ES (1) | ES2355827T3 (de) |
FR (1) | FR2857971B1 (de) |
GT (1) | GT200400145A (de) |
HK (1) | HK1094806A1 (de) |
HN (1) | HN2004000250A (de) |
IL (1) | IL173206A (de) |
MA (1) | MA27928A1 (de) |
ME (1) | MEP11608A (de) |
MX (1) | MXPA06000336A (de) |
MY (1) | MY136769A (de) |
NO (1) | NO20060821L (de) |
NZ (1) | NZ544717A (de) |
OA (1) | OA13197A (de) |
PA (1) | PA8606801A1 (de) |
PE (1) | PE20050246A1 (de) |
PL (1) | PL1651677T3 (de) |
PT (1) | PT1651677E (de) |
RS (1) | RS20060044A (de) |
RU (1) | RU2346005C2 (de) |
SI (1) | SI1651677T1 (de) |
TN (1) | TNSN06025A1 (de) |
TW (1) | TWI369208B (de) |
UA (1) | UA89356C2 (de) |
UY (1) | UY28435A1 (de) |
WO (1) | WO2005010051A2 (de) |
ZA (1) | ZA200600657B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7589145B2 (en) | 2004-04-15 | 2009-09-15 | Exxonmobil Chemical Patents Inc. | Syndiotactic rich polyolefins |
EP2404939A3 (de) * | 2006-05-25 | 2012-03-21 | Momenta Pharmaceuticals, Inc. | Heparinzusammensetzung mit geringem Molekulargewicht und Anwendungen dafür |
CN101711771B (zh) * | 2008-10-07 | 2015-12-09 | 上海喜恩医药科技发展有限公司 | 一种肝素衍生的多糖混合物及其制法和药物组合物 |
KR101847846B1 (ko) * | 2010-09-14 | 2018-04-11 | 고쿠리츠 다이가쿠 호징 미야자키 다이가쿠 | 고순도 헤파린 및 그 제조방법 |
WO2012072799A1 (en) | 2010-12-02 | 2012-06-07 | Aventis Pharma S.A. | New methods for the in vitro measurement of the biological activity of an ultra low molecular weight heparin sample |
CN102558392A (zh) * | 2010-12-14 | 2012-07-11 | 王芃 | 一种高抗FXa、低抗FIIa低分子肝素钠的制备方法 |
CN102816255B (zh) * | 2011-06-10 | 2015-11-25 | 王芃 | 一种超低分子肝素钠的制备方法 |
WO2014153995A1 (zh) * | 2013-03-26 | 2014-10-02 | 中国科学院昆明植物研究所 | 一种低分子量糖胺聚糖衍生物及其药物组合物和其制备方法与应用 |
CN103864959A (zh) * | 2014-04-03 | 2014-06-18 | 中国药科大学 | 一种肝素十二糖抗动脉粥样硬化的用途 |
RU2639574C2 (ru) * | 2016-05-23 | 2017-12-21 | Алексей Георгиевич Александров | Способ получения низкомолекулярного гепарина |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL61201A (en) * | 1979-10-05 | 1984-09-30 | Choay Sa | Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them |
FR2504928A1 (fr) * | 1981-04-29 | 1982-11-05 | Choay Sa | Oligosaccharides a chaines courtes possedant des proprietes biologiques, leur preparation et leurs applications en tant que medicaments |
WO1998055515A1 (en) * | 1997-06-06 | 1998-12-10 | Hamilton Civic Hospitals Research Development, Inc. | Modified low molecular weight heparin that inhibits clot associated coagulation factors |
ES2161615B1 (es) * | 1999-07-23 | 2003-03-16 | Rovi Lab Farmaceut Sa | Composiciones de heparinas de muy bajo peso molecular. |
JP4897991B2 (ja) * | 1999-07-23 | 2012-03-14 | ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ | 超低分子量ヘパリン組成物 |
FR2800074B1 (fr) * | 1999-10-22 | 2001-12-21 | Aventis Pharma Sa | Nouveaux oligosaccharides, leur preparation et les compositions pharmaceutiques les contenant |
JP4585072B2 (ja) * | 2000-02-29 | 2010-11-24 | 扶桑薬品工業株式会社 | ヘパリン解重合法、解重合ヘパリン、その誘導体および医薬組成物 |
FR2807043B1 (fr) * | 2000-03-28 | 2002-11-22 | Aventis Pharma Sa | Composition pharmaceutique contenant des oligosaccharides, les nouveaux oligosaccharides et leur preparation |
FR2811992B1 (fr) * | 2000-07-21 | 2003-07-04 | Aventis Pharma Sa | Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant |
US6969705B2 (en) * | 2000-07-21 | 2005-11-29 | Aventis Pharma S.A. | Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them |
CA2458852A1 (en) * | 2001-08-28 | 2003-03-06 | Leo Pharma A/S | Antithrombotic compositions comprising low molecular weight heparin and low molecular weight dermatan sulphate |
FR2845686B1 (fr) * | 2002-10-10 | 2013-08-30 | Aventis Pharma Sa | Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant |
-
2003
- 2003-07-24 FR FR0309041A patent/FR2857971B1/fr not_active Expired - Fee Related
-
2004
- 2004-07-01 PE PE2004000632A patent/PE20050246A1/es not_active Application Discontinuation
- 2004-07-14 PA PA20048606801A patent/PA8606801A1/es unknown
- 2004-07-19 AR ARP040102549A patent/AR045917A1/es not_active Application Discontinuation
- 2004-07-21 HN HN2004000250A patent/HN2004000250A/es unknown
- 2004-07-22 ME MEP-116/08A patent/MEP11608A/xx unknown
- 2004-07-22 PT PT04785991T patent/PT1651677E/pt unknown
- 2004-07-22 JP JP2006520862A patent/JP4865552B2/ja not_active Expired - Fee Related
- 2004-07-22 MY MYPI20042944A patent/MY136769A/en unknown
- 2004-07-22 RS YUP-2006/0044A patent/RS20060044A/sr unknown
- 2004-07-22 DE DE602004030015T patent/DE602004030015D1/de active Active
- 2004-07-22 SI SI200431594T patent/SI1651677T1/sl unknown
- 2004-07-22 CN CN2004800265420A patent/CN1852926B/zh not_active Expired - Fee Related
- 2004-07-22 AT AT04785991T patent/ATE487741T1/de active
- 2004-07-22 OA OA1200600025A patent/OA13197A/fr unknown
- 2004-07-22 EP EP04785991A patent/EP1651677B1/de active Active
- 2004-07-22 BR BRPI0412850-8A patent/BRPI0412850A/pt active Search and Examination
- 2004-07-22 UA UAA200601969A patent/UA89356C2/ru unknown
- 2004-07-22 ES ES04785991T patent/ES2355827T3/es active Active
- 2004-07-22 NZ NZ544717A patent/NZ544717A/en unknown
- 2004-07-22 WO PCT/FR2004/001943 patent/WO2005010051A2/fr active Application Filing
- 2004-07-22 DK DK04785991.3T patent/DK1651677T3/da active
- 2004-07-22 AU AU2004259111A patent/AU2004259111B2/en not_active Ceased
- 2004-07-22 RU RU2006105384/04A patent/RU2346005C2/ru not_active IP Right Cessation
- 2004-07-22 MX MXPA06000336A patent/MXPA06000336A/es active IP Right Grant
- 2004-07-22 KR KR1020067001609A patent/KR101125517B1/ko not_active IP Right Cessation
- 2004-07-22 PL PL04785991T patent/PL1651677T3/pl unknown
- 2004-07-22 CA CA002533555A patent/CA2533555A1/fr not_active Abandoned
- 2004-07-23 UY UY28435A patent/UY28435A1/es unknown
- 2004-07-23 TW TW093121979A patent/TWI369208B/zh not_active IP Right Cessation
- 2004-07-23 GT GT200400145A patent/GT200400145A/es unknown
-
2006
- 2006-01-17 IL IL173206A patent/IL173206A/en not_active IP Right Cessation
- 2006-01-18 CR CR8201A patent/CR8201A/es unknown
- 2006-01-20 MA MA28745A patent/MA27928A1/fr unknown
- 2006-01-23 TN TNP2006000025A patent/TNSN06025A1/en unknown
- 2006-01-23 ZA ZA200600657A patent/ZA200600657B/en unknown
- 2006-01-23 EC EC2006006305A patent/ECSP066305A/es unknown
- 2006-02-20 NO NO20060821A patent/NO20060821L/no not_active Application Discontinuation
-
2007
- 2007-01-10 HK HK07100324.0A patent/HK1094806A1/xx not_active IP Right Cessation
-
2011
- 2011-02-04 CY CY20111100132T patent/CY1111165T1/el unknown
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