MY127212A - New pyridine-substituted pyrazolopyridine derivatives - Google Patents

New pyridine-substituted pyrazolopyridine derivatives

Info

Publication number
MY127212A
MY127212A MYPI20015302A MYPI20015302A MY127212A MY 127212 A MY127212 A MY 127212A MY PI20015302 A MYPI20015302 A MY PI20015302A MY PI20015302 A MYPI20015302 A MY PI20015302A MY 127212 A MY127212 A MY 127212A
Authority
MY
Malaysia
Prior art keywords
pyrazolopyridine derivatives
new pyridine
disorders
substituted pyrazolopyridine
treatment
Prior art date
Application number
MYPI20015302A
Inventor
Johannes-Peter Stasch Dr
Elisabeth Perzborn Dr
Alexander Straub Dr
Achim Feurer Dr
Cristina Alonso-Alija Dr
Elke Stahl Dr
Klaus Dembowsky Dr
Dietmar Flubacher Dr
Frank Wunder Dr
Stefan Weigand Dr
Dieter Lang Dr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MY127212A publication Critical patent/MY127212A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

THE PRESENT INVENTION RELATES TO NEW PYRAZOLOPYRIDINE OF THE FORMULA (1) IN WHICH R1 REPRESENTS 4-PYRIDINYL OR 3-PIRIDINYL; R2 REPRESENTS H, NH2 OR HALOGEN; AND SALTS, ISOMERS AND HYDRATES THEREOF AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE AND FOR USE AGENTS FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS, HYPERTENSION, OF THROMBOEMBOLIC DISORDERS AND ISCHAEMIA, SEXUAL DYSFUNCTION OR INFLAMMATION, AND FOR THE TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM.
MYPI20015302A 2000-11-22 2001-11-20 New pyridine-substituted pyrazolopyridine derivatives MY127212A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10057753 2000-11-22
DE10131987A DE10131987A1 (en) 2000-11-22 2001-07-02 New pyridinyl-substituted pyrazolo (3,4-b) pyridine derivatives, are soluble guanylate cyclase stimulants useful e.g. for treating cardiovascular or central nervous system diseases, sexual dysfunction or inflammation

Publications (1)

Publication Number Publication Date
MY127212A true MY127212A (en) 2006-11-30

Family

ID=7664122

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20015302A MY127212A (en) 2000-11-22 2001-11-20 New pyridine-substituted pyrazolopyridine derivatives

Country Status (12)

Country Link
KR (1) KR20030065519A (en)
DE (2) DE10131987A1 (en)
DO (1) DOP2001000291A (en)
EC (1) ECSP034616A (en)
GT (1) GT200100235A (en)
HN (1) HN2001000261A (en)
MY (1) MY127212A (en)
PE (1) PE20020581A1 (en)
RU (1) RU2003118584A (en)
SV (1) SV2003000743A (en)
UA (1) UA74404C2 (en)
ZA (1) ZA200303887B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102485724B (en) * 2010-12-06 2015-08-12 中国人民解放军军事医学科学院毒物药物研究所 Substituted thiophene base pyrazolo-pyridines and medicinal use thereof
WO2013076168A1 (en) 2011-11-25 2013-05-30 Bayer Pharma Aktiengesellschaft Method for producing substituted 5-fluoro-1h-pyrazolopyridines
WO2018069126A1 (en) * 2016-10-11 2018-04-19 Bayer Pharma Aktiengesellschaft Combination containing sgc stimulators and mineralocorticoid receptor antagonists

Also Published As

Publication number Publication date
GT200100235A (en) 2002-06-25
DE10131987A1 (en) 2002-05-23
KR20030065519A (en) 2003-08-06
RU2003118584A (en) 2004-12-20
ZA200303887B (en) 2004-06-21
PE20020581A1 (en) 2002-07-13
ECSP034616A (en) 2003-06-25
DOP2001000291A (en) 2002-12-15
UA74404C2 (en) 2005-12-15
SV2003000743A (en) 2003-01-13
HN2001000261A (en) 2002-01-30
DE50106655D1 (en) 2005-08-04

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