GT200100235A - NEW DERIVATIVES OF PIRAZOLPIRIDINA REPLACED WITH PIRIDINE. - Google Patents

NEW DERIVATIVES OF PIRAZOLPIRIDINA REPLACED WITH PIRIDINE.

Info

Publication number
GT200100235A
GT200100235A GT200100235A GT200100235A GT200100235A GT 200100235 A GT200100235 A GT 200100235A GT 200100235 A GT200100235 A GT 200100235A GT 200100235 A GT200100235 A GT 200100235A GT 200100235 A GT200100235 A GT 200100235A
Authority
GT
Guatemala
Prior art keywords
diseases
pirazolpiridina
piridine
replaced
new derivatives
Prior art date
Application number
GT200100235A
Other languages
Spanish (es)
Inventor
Johannes-Peter Stasch
Achim Feurer
Stefan Weigand
Elke Stahl
Dietmar Flubacher
Cristina Alonso-Alija
Frank Wunder
Dieter Lang
Klaus Dembowsky
Alexander Straub
Elisabeth Perzborn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200100235A publication Critical patent/GT200100235A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A DERIVADOS DE PIRAZOLPIRIDINA DE FORMULA I EN DONDE R1 Y R2 SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. TAMBIEN SE REFIERE SUS SALES, ISOMEROS E HIDRATOS DE LOS MISMOS QUE ACTUAN COMO ESTIMULADORES DE LA GUANILATO CICLASA SOLUBLE Y PARA LA UTILIZACION COMO AGENTES PARA EL TRATAMIENTO DE ENFERMEDADES CORONARIOCIRCULATORIAS, HIPERTONIA, ENFERMEDADES TROMBOEMBOLICAS E ISQUEMIAS, DISFUNCION SEXUAL O INFLAMACIONES ASI COMO PARA EL TRATAMIENTO DE ENFERMEDADES DEL SISTEMA NERVIOSO CENTRAL.THE PRESENT INVENTION REFERS TO PIRAZOLPIRIDINE DERIVATIVES OF FORMULA I WHERE R1 AND R2 ARE FUNCTIONAL GROUPS DESCRIBED IN THE RECORD. IT IS ALSO REFERRED TO ITS SALTS, ISOMEROS AND HYDRAPHS OF THE SAME ACTING AS STIMULATORS OF THE SUBBLE GUANILATE CYCLING AND FOR THE USE AS AGENTS FOR THE TREATMENT OF CORONARY CIRCULULATORY DISEASES, HYPERTONIA, DISEASES ASSOCIATION THERMAL DISEASES ASSOCIATIONS OF DISEASES OF THE CENTRAL NERVOUS SYSTEM.

GT200100235A 2000-11-22 2001-11-22 NEW DERIVATIVES OF PIRAZOLPIRIDINA REPLACED WITH PIRIDINE. GT200100235A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10057753 2000-11-22

Publications (1)

Publication Number Publication Date
GT200100235A true GT200100235A (en) 2002-06-25

Family

ID=7664122

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200100235A GT200100235A (en) 2000-11-22 2001-11-22 NEW DERIVATIVES OF PIRAZOLPIRIDINA REPLACED WITH PIRIDINE.

Country Status (12)

Country Link
KR (1) KR20030065519A (en)
DE (2) DE10131987A1 (en)
DO (1) DOP2001000291A (en)
EC (1) ECSP034616A (en)
GT (1) GT200100235A (en)
HN (1) HN2001000261A (en)
MY (1) MY127212A (en)
PE (1) PE20020581A1 (en)
RU (1) RU2003118584A (en)
SV (1) SV2003000743A (en)
UA (1) UA74404C2 (en)
ZA (1) ZA200303887B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102485724B (en) * 2010-12-06 2015-08-12 中国人民解放军军事医学科学院毒物药物研究所 Substituted thiophene base pyrazolo-pyridines and medicinal use thereof
DK2782914T3 (en) 2011-11-25 2018-11-26 Adverio Pharma Gmbh PROCEDURE FOR PREPARING SUBSTITUTED 5-FLUOR-1H-PYRAZOLOPYRIDINES
US10918639B2 (en) * 2016-10-11 2021-02-16 Bayer Pharma Aktiengesellschaft Combination containing SGC stimulators and mineralocorticoid receptor antagonists

Also Published As

Publication number Publication date
RU2003118584A (en) 2004-12-20
HN2001000261A (en) 2002-01-30
SV2003000743A (en) 2003-01-13
ZA200303887B (en) 2004-06-21
MY127212A (en) 2006-11-30
UA74404C2 (en) 2005-12-15
ECSP034616A (en) 2003-06-25
DE10131987A1 (en) 2002-05-23
DE50106655D1 (en) 2005-08-04
PE20020581A1 (en) 2002-07-13
KR20030065519A (en) 2003-08-06
DOP2001000291A (en) 2002-12-15

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