SV2003000743A - NEW DERIVATIVES OF PIRAZOLPIRIDINA REPLACED WITH PIRIDINA REF. READ 34888-SV - Google Patents

NEW DERIVATIVES OF PIRAZOLPIRIDINA REPLACED WITH PIRIDINA REF. READ 34888-SV

Info

Publication number
SV2003000743A
SV2003000743A SV2001000743A SV2001000743A SV2003000743A SV 2003000743 A SV2003000743 A SV 2003000743A SV 2001000743 A SV2001000743 A SV 2001000743A SV 2001000743 A SV2001000743 A SV 2001000743A SV 2003000743 A SV2003000743 A SV 2003000743A
Authority
SV
El Salvador
Prior art keywords
new derivatives
pirazolpiridina
piridina
ref
replaced
Prior art date
Application number
SV2001000743A
Other languages
Spanish (es)
Inventor
Johannes Peter Stasch
Achim Feurer
Stefan Weigand
Elke Stahl
Dietmar Flubacher
Alija Cristina Alonso
Frank Wunder
Dieter Lang
Klaus Dembowsky
Alexander Straub
Elisabeth Perzborn
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SV2003000743A publication Critical patent/SV2003000743A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVOS DERIVADOS DE PIRAZOLPIRIDINA DE FORMULA I, EN LA QUE R1 REPRESENTA 4-PIRIDINILO O 3-PIRIDINILO; R2 REPRESENTA H, HN2 O HALOGENO; ASI COMO SALES, ISOMEROS E HIDRATOS DE LOS MISMOS COMO ESTIMULADORES DE LA GUANILATO CICLASA SOLUBLE Y PARA LA UTILIZACION COMO AGENTE PARA EL TRATAMIENTO DE ENFERMEDADES CORONARIO-CIRCULATORIAS, HIPERTONIA, ENFERMEDADES TROMBOEMBOLICAS E ISQUEMIAS, DISFUNCION SEXUAL O INFLAMACIONES ASI COMO PARA EL TRATAMIENTO DE ENFERMEDAES DEL SISTEMA NERVIOSO CENTRALTHIS INVENTION REFERS TO NEW DERIVATIVES OF PIRAZOLPIRIDINE OF FORMULA I, IN WHICH R1 REPRESENTS 4-PIRIDINYL OR 3-PIRIDINYL; R2 REPRESENTS H, HN2 OR HALOGEN; AS WELL AS SALTS, ISOMEROS AND HYDRAPHS OF THE SAME AS STIMULATORS OF THE SOLUBLE CYCLASE GUANILATE AND FOR THE USE AS AN AGENT FOR THE TREATMENT OF CORONARY-CIRCULATORY DISEASES, HYPERTONIA, THROMBROBEMICAL DISEASES OR DISEASE ASFORMATION OF THE CENTRAL NERVOUS SYSTEM

SV2001000743A 2000-11-22 2001-11-21 NEW DERIVATIVES OF PIRAZOLPIRIDINA REPLACED WITH PIRIDINA REF. READ 34888-SV SV2003000743A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10057753 2000-11-22
DE10131987A DE10131987A1 (en) 2000-11-22 2001-07-02 New pyridinyl-substituted pyrazolo (3,4-b) pyridine derivatives, are soluble guanylate cyclase stimulants useful e.g. for treating cardiovascular or central nervous system diseases, sexual dysfunction or inflammation

Publications (1)

Publication Number Publication Date
SV2003000743A true SV2003000743A (en) 2003-01-13

Family

ID=7664122

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2001000743A SV2003000743A (en) 2000-11-22 2001-11-21 NEW DERIVATIVES OF PIRAZOLPIRIDINA REPLACED WITH PIRIDINA REF. READ 34888-SV

Country Status (12)

Country Link
KR (1) KR20030065519A (en)
DE (2) DE10131987A1 (en)
DO (1) DOP2001000291A (en)
EC (1) ECSP034616A (en)
GT (1) GT200100235A (en)
HN (1) HN2001000261A (en)
MY (1) MY127212A (en)
PE (1) PE20020581A1 (en)
RU (1) RU2003118584A (en)
SV (1) SV2003000743A (en)
UA (1) UA74404C2 (en)
ZA (1) ZA200303887B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102485724B (en) * 2010-12-06 2015-08-12 中国人民解放军军事医学科学院毒物药物研究所 Substituted thiophene base pyrazolo-pyridines and medicinal use thereof
CR20190057A (en) 2011-11-25 2019-04-23 Adverio Pharma Gmbh Method for producing substituted 5-fluoro-1h-pyrazolopyridines
CN110022871A (en) * 2016-10-11 2019-07-16 拜耳制药股份公司 Combination product comprising sGC stimulant and mineralocorticoid receptor antagonists

Also Published As

Publication number Publication date
ECSP034616A (en) 2003-06-25
DE50106655D1 (en) 2005-08-04
DE10131987A1 (en) 2002-05-23
ZA200303887B (en) 2004-06-21
PE20020581A1 (en) 2002-07-13
MY127212A (en) 2006-11-30
RU2003118584A (en) 2004-12-20
KR20030065519A (en) 2003-08-06
GT200100235A (en) 2002-06-25
HN2001000261A (en) 2002-01-30
DOP2001000291A (en) 2002-12-15
UA74404C2 (en) 2005-12-15

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