UA74404C2 - pyrazolopyridine pyridine substituted derivatives - Google Patents
pyrazolopyridine pyridine substituted derivativesInfo
- Publication number
- UA74404C2 UA74404C2 UA2003065752A UA200365752A UA74404C2 UA 74404 C2 UA74404 C2 UA 74404C2 UA 2003065752 A UA2003065752 A UA 2003065752A UA 200365752 A UA200365752 A UA 200365752A UA 74404 C2 UA74404 C2 UA 74404C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pyrazolopyridine
- substituted derivatives
- pyridine substituted
- diseases
- treating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The invention relates to novel pyrazolopyridine derivatives of the formula (I), wherein R1 represents 4-pyridinyi or 3-pyridinyl; R2 represents H, NH2 or halogen, and to the salts, isomers and hydrates thereof as stimulators of the soluble guanylate cyclase and for the use as agents for treating cardiovascular diseases, hypertonia, thromboembolic diseases and ischemias, sexual dysfunction or inflammations and for treating diseases of the central nervous system.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10057753 | 2000-11-22 | ||
DE10131987A DE10131987A1 (en) | 2000-11-22 | 2001-07-02 | New pyridinyl-substituted pyrazolo (3,4-b) pyridine derivatives, are soluble guanylate cyclase stimulants useful e.g. for treating cardiovascular or central nervous system diseases, sexual dysfunction or inflammation |
PCT/EP2001/012969 WO2002042301A1 (en) | 2000-11-22 | 2001-11-09 | Novel pyridine-substituted pyrazolopyridine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
UA74404C2 true UA74404C2 (en) | 2005-12-15 |
Family
ID=7664122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA2003065752A UA74404C2 (en) | 2000-11-22 | 2001-11-09 | pyrazolopyridine pyridine substituted derivatives |
Country Status (12)
Country | Link |
---|---|
KR (1) | KR20030065519A (en) |
DE (2) | DE10131987A1 (en) |
DO (1) | DOP2001000291A (en) |
EC (1) | ECSP034616A (en) |
GT (1) | GT200100235A (en) |
HN (1) | HN2001000261A (en) |
MY (1) | MY127212A (en) |
PE (1) | PE20020581A1 (en) |
RU (1) | RU2003118584A (en) |
SV (1) | SV2003000743A (en) |
UA (1) | UA74404C2 (en) |
ZA (1) | ZA200303887B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102485724B (en) * | 2010-12-06 | 2015-08-12 | 中国人民解放军军事医学科学院毒物药物研究所 | Substituted thiophene base pyrazolo-pyridines and medicinal use thereof |
DK2782914T3 (en) | 2011-11-25 | 2018-11-26 | Adverio Pharma Gmbh | PROCEDURE FOR PREPARING SUBSTITUTED 5-FLUOR-1H-PYRAZOLOPYRIDINES |
US10918639B2 (en) * | 2016-10-11 | 2021-02-16 | Bayer Pharma Aktiengesellschaft | Combination containing SGC stimulators and mineralocorticoid receptor antagonists |
-
2001
- 2001-07-02 DE DE10131987A patent/DE10131987A1/en not_active Withdrawn
- 2001-11-09 RU RU2003118584/04A patent/RU2003118584A/en not_active Application Discontinuation
- 2001-11-09 UA UA2003065752A patent/UA74404C2/en unknown
- 2001-11-09 DE DE50106655T patent/DE50106655D1/en not_active Expired - Lifetime
- 2001-11-09 KR KR10-2003-7006853A patent/KR20030065519A/en not_active Application Discontinuation
- 2001-11-20 MY MYPI20015302A patent/MY127212A/en unknown
- 2001-11-20 DO DO2001000291A patent/DOP2001000291A/en unknown
- 2001-11-21 SV SV2001000743A patent/SV2003000743A/en unknown
- 2001-11-21 PE PE2001001161A patent/PE20020581A1/en not_active Application Discontinuation
- 2001-11-21 HN HN2001000261A patent/HN2001000261A/en unknown
- 2001-11-22 GT GT200100235A patent/GT200100235A/en unknown
-
2003
- 2003-05-19 ZA ZA200303887A patent/ZA200303887B/en unknown
- 2003-05-21 EC EC2003004616A patent/ECSP034616A/en unknown
Also Published As
Publication number | Publication date |
---|---|
GT200100235A (en) | 2002-06-25 |
RU2003118584A (en) | 2004-12-20 |
HN2001000261A (en) | 2002-01-30 |
SV2003000743A (en) | 2003-01-13 |
ZA200303887B (en) | 2004-06-21 |
MY127212A (en) | 2006-11-30 |
ECSP034616A (en) | 2003-06-25 |
DE10131987A1 (en) | 2002-05-23 |
DE50106655D1 (en) | 2005-08-04 |
PE20020581A1 (en) | 2002-07-13 |
KR20030065519A (en) | 2003-08-06 |
DOP2001000291A (en) | 2002-12-15 |
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