MXPA06000539A - Derivado novedoso de heteroarilo. - Google Patents
Derivado novedoso de heteroarilo.Info
- Publication number
- MXPA06000539A MXPA06000539A MXPA06000539A MXPA06000539A MXPA06000539A MX PA06000539 A MXPA06000539 A MX PA06000539A MX PA06000539 A MXPA06000539 A MX PA06000539A MX PA06000539 A MXPA06000539 A MX PA06000539A MX PA06000539 A MXPA06000539 A MX PA06000539A
- Authority
- MX
- Mexico
- Prior art keywords
- substituted
- heteroaryl
- heteroaryl derivative
- novel heteroaryl
- formula
- Prior art date
Links
- 125000001072 heteroaryl group Chemical group 0.000 title abstract 4
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000732 arylene group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000005549 heteroarylene group Chemical group 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003274684 | 2003-07-15 | ||
| PCT/JP2004/010282 WO2005012245A1 (ja) | 2003-07-15 | 2004-07-13 | 新規ヘテロアリール誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA06000539A true MXPA06000539A (es) | 2006-03-30 |
Family
ID=34113749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA06000539A MXPA06000539A (es) | 2003-07-15 | 2004-07-13 | Derivado novedoso de heteroarilo. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7425642B2 (https=) |
| EP (1) | EP1647546B1 (https=) |
| JP (2) | JP4820169B2 (https=) |
| KR (1) | KR101086654B1 (https=) |
| CN (1) | CN100516041C (https=) |
| AT (1) | ATE556051T1 (https=) |
| CA (1) | CA2531064C (https=) |
| ES (1) | ES2383895T3 (https=) |
| MX (1) | MXPA06000539A (https=) |
| TW (1) | TW200523249A (https=) |
| WO (1) | WO2005012245A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006075638A1 (ja) * | 2005-01-14 | 2006-07-20 | Dainippon Sumitomo Pharma Co., Ltd. | 新規ヘテロアリール誘導体 |
| US20060241073A1 (en) * | 2005-04-20 | 2006-10-26 | Wanders Ronaldus J A | Means and methods for counteracting fatty acid accumulation |
| TWI386405B (zh) | 2006-09-05 | 2013-02-21 | 咪唑衍生物 | |
| WO2008157537A2 (en) * | 2007-06-19 | 2008-12-24 | Ironwood Pharmaceuticals, Inc | Compositions and methods of use for treating or preventing lipid related disorders |
| CN102202662A (zh) * | 2008-10-31 | 2011-09-28 | 大日本住友制药株式会社 | 抗糖尿病剂 |
| US20120010264A1 (en) * | 2009-03-26 | 2012-01-12 | Dainippon Sumitomo Pharma Co., Ltd. | Novel medicament for treating cognitive impairment |
| WO2011002012A1 (ja) * | 2009-07-01 | 2011-01-06 | 大日本住友製薬株式会社 | Sglt1阻害薬とインスリン抵抗性改善薬を組み合わせてなる医薬 |
| KR20120117905A (ko) | 2010-01-28 | 2012-10-24 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 프로테아좀 활성을 향상시키는 조성물 및 방법 |
| JP5996532B2 (ja) | 2010-07-15 | 2016-09-21 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | 有害生物防除剤としての新規複素環式化合物 |
| HUE044867T2 (hu) | 2011-05-12 | 2019-11-28 | Proteostasis Therapeutics Inc | Proteosztázis szabályzók |
| US10266490B2 (en) * | 2012-03-16 | 2019-04-23 | Georgetown University | Radioprotector compounds |
| US9849135B2 (en) | 2013-01-25 | 2017-12-26 | President And Fellows Of Harvard College | USP14 inhibitors for treating or preventing viral infections |
| WO2015073528A1 (en) | 2013-11-12 | 2015-05-21 | Proteostasis Therapeutics, Inc. | Proteasome activity enhancing compounds |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2752361A1 (de) * | 1977-11-24 | 1979-06-07 | Troponwerke Gmbh & Co Kg | Neue indolderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| EP0973778A1 (en) * | 1997-03-07 | 2000-01-26 | Novo Nordisk A/S | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE |
| US6177443B1 (en) | 1997-03-07 | 2001-01-23 | Novo Nordisk A/S | 4,5,6,7-tetrahydro-thieno[3, 2-C]pyridine derivatives, their preparation and use |
| EP1284260A4 (en) | 2000-05-22 | 2004-03-31 | Takeda Chemical Industries Ltd | TYROSIN PHOSPHATASE INHIBITORS |
| JP2002121186A (ja) * | 2000-05-22 | 2002-04-23 | Takeda Chem Ind Ltd | チロシンホスファターゼ阻害剤 |
| ATE423120T1 (de) * | 2000-06-26 | 2009-03-15 | Pfizer Prod Inc | Pyrroloä2,3-düpyrimidin verbindungen als immunosuppressive wirkstoffe |
| EP1386913B1 (en) * | 2001-04-19 | 2008-07-16 | Dainippon Sumitomo Pharma Co., Ltd. | Pyrrole derivative |
| JP2003171275A (ja) | 2001-12-11 | 2003-06-17 | Sumitomo Pharmaceut Co Ltd | ＰＰＡＲδアゴニスト |
| JPWO2004048341A1 (ja) | 2002-11-28 | 2006-03-23 | 住友製薬株式会社 | 新規ヘテロアリール誘導体 |
-
2004
- 2004-07-13 CN CNB2004800262352A patent/CN100516041C/zh not_active Expired - Fee Related
- 2004-07-13 US US10/563,361 patent/US7425642B2/en not_active Expired - Fee Related
- 2004-07-13 KR KR1020067000907A patent/KR101086654B1/ko not_active Expired - Fee Related
- 2004-07-13 ES ES04747746T patent/ES2383895T3/es not_active Expired - Lifetime
- 2004-07-13 MX MXPA06000539A patent/MXPA06000539A/es active IP Right Grant
- 2004-07-13 JP JP2005512472A patent/JP4820169B2/ja not_active Expired - Fee Related
- 2004-07-13 EP EP04747746A patent/EP1647546B1/en not_active Expired - Lifetime
- 2004-07-13 CA CA2531064A patent/CA2531064C/en not_active Expired - Fee Related
- 2004-07-13 WO PCT/JP2004/010282 patent/WO2005012245A1/ja not_active Ceased
- 2004-07-13 AT AT04747746T patent/ATE556051T1/de active
- 2004-07-15 TW TW093121149A patent/TW200523249A/zh not_active IP Right Cessation
-
2008
- 2008-07-15 US US12/173,792 patent/US20080306275A1/en not_active Abandoned
-
2011
- 2011-07-07 JP JP2011151138A patent/JP2011251974A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1849303A (zh) | 2006-10-18 |
| JP2011251974A (ja) | 2011-12-15 |
| TWI331142B (https=) | 2010-10-01 |
| KR20060040681A (ko) | 2006-05-10 |
| EP1647546A1 (en) | 2006-04-19 |
| US20060194857A1 (en) | 2006-08-31 |
| US7425642B2 (en) | 2008-09-16 |
| US20080306275A1 (en) | 2008-12-11 |
| WO2005012245A1 (ja) | 2005-02-10 |
| JPWO2005012245A1 (ja) | 2006-09-14 |
| CN100516041C (zh) | 2009-07-22 |
| CA2531064A1 (en) | 2005-02-10 |
| TW200523249A (en) | 2005-07-16 |
| JP4820169B2 (ja) | 2011-11-24 |
| CA2531064C (en) | 2012-05-22 |
| ATE556051T1 (de) | 2012-05-15 |
| EP1647546A4 (en) | 2008-07-23 |
| KR101086654B1 (ko) | 2011-11-24 |
| ES2383895T3 (es) | 2012-06-27 |
| HK1087409A1 (en) | 2006-10-13 |
| EP1647546B1 (en) | 2012-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |