MXPA05009835A - Reduccion de efecto de gancho en dispositivos de ensayo. - Google Patents

Reduccion de efecto de gancho en dispositivos de ensayo.

Info

Publication number
MXPA05009835A
MXPA05009835A MXPA05009835A MXPA05009835A MXPA05009835A MX PA05009835 A MXPA05009835 A MX PA05009835A MX PA05009835 A MXPA05009835 A MX PA05009835A MX PA05009835 A MXPA05009835 A MX PA05009835A MX PA05009835 A MXPA05009835 A MX PA05009835A
Authority
MX
Mexico
Prior art keywords
analyte
specific binding
binding member
reduction
test sample
Prior art date
Application number
MXPA05009835A
Other languages
English (en)
Inventor
Yang Kaiyuan
Original Assignee
Kimberly Clark Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kimberly Clark Co filed Critical Kimberly Clark Co
Publication of MXPA05009835A publication Critical patent/MXPA05009835A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Es proporcionado un dispositivo de ensayo a base de membrana para detectar la presencia o la cantidad de un analito que reside en la muestra de prueba. El dispositivo utiliza sondas conjugadas que contienen un miembro aglutinante especifico para el analito de interes. El miembro aglutinante especifico preferiblemente con el analito dentro de una muestra de prueba cuando se pone en contacto con la misma. El analito en exceso que permanece no complejado con el miembro aglutinante especifico sufre un aglutinamiento no especifico, tal como a un dominio hidrofobico. Como resultado, la capacidad del analito no complejado para competir con el analito complejado en la zona de deteccion del dispositivo se restringe. Por tanto, la incidencia de "negativos falsos" es limitada en una manera simple, eficiente y relativamente barata.
MXPA05009835A 2003-04-03 2004-03-03 Reduccion de efecto de gancho en dispositivos de ensayo. MXPA05009835A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/406,631 US7851209B2 (en) 2003-04-03 2003-04-03 Reduction of the hook effect in assay devices
PCT/US2004/006414 WO2004095030A1 (en) 2003-04-03 2004-03-03 Reduction of the hook effect in assay devices

Publications (1)

Publication Number Publication Date
MXPA05009835A true MXPA05009835A (es) 2005-12-05

Family

ID=33097350

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05009835A MXPA05009835A (es) 2003-04-03 2004-03-03 Reduccion de efecto de gancho en dispositivos de ensayo.

Country Status (9)

Country Link
US (1) US7851209B2 (es)
EP (1) EP1608981B1 (es)
KR (1) KR101057918B1 (es)
CN (1) CN1761880B (es)
AU (1) AU2004232218A1 (es)
CA (1) CA2513895C (es)
MX (1) MXPA05009835A (es)
TW (1) TW200426369A (es)
WO (1) WO2004095030A1 (es)

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KR101858765B1 (ko) 2010-03-31 2018-05-16 세키스이 메디칼 가부시키가이샤 면역 크로마토그래피를 이용한 측정 방법, 면역 크로마토그래피용 테스트 스트립 및 면역 크로마토그래피용 측정 시약 키트
CN103917638A (zh) * 2011-09-08 2014-07-09 Nexusdx股份有限公司 多级分析物检定
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CN104034893B (zh) * 2013-03-08 2016-04-20 北京普析通用仪器有限责任公司 一种基于胶乳的三聚氰胺快速检测方法及试剂盒
CN107567588A (zh) * 2015-05-19 2018-01-09 雀巢产品技术援助有限公司 用于鉴定母乳缺失岩藻糖基转移酶‑2相关聚糖以及喂食一定剂量所述聚糖的成套试剂盒
CN109470864A (zh) * 2016-11-22 2019-03-15 博阳生物科技（上海）有限公司 免疫测定方法、用于鉴定免疫测定的系统和试剂盒

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