MXPA05004395A - Composiciones de milnacipran de liberacion modificada. - Google Patents
Composiciones de milnacipran de liberacion modificada.Info
- Publication number
- MXPA05004395A MXPA05004395A MXPA05004395A MXPA05004395A MXPA05004395A MX PA05004395 A MXPA05004395 A MX PA05004395A MX PA05004395 A MXPA05004395 A MX PA05004395A MX PA05004395 A MXPA05004395 A MX PA05004395A MX PA05004395 A MXPA05004395 A MX PA05004395A
- Authority
- MX
- Mexico
- Prior art keywords
- milnacipran
- release
- hours
- composition
- drug
- Prior art date
Links
- GJJFMKBJSRMPLA-HIFRSBDPSA-N (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-1-cyclopropanecarboxamide Chemical group C=1C=CC=CC=1[C@@]1(C(=O)N(CC)CC)C[C@@H]1CN GJJFMKBJSRMPLA-HIFRSBDPSA-N 0.000 title abstract 7
- 229960000600 milnacipran Drugs 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 6
- 229940079593 drug Drugs 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 208000008454 Hyperhidrosis Diseases 0.000 abstract 2
- 206010044565 Tremor Diseases 0.000 abstract 2
- 238000013265 extended release Methods 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 208000004998 Abdominal Pain Diseases 0.000 abstract 1
- 206010001497 Agitation Diseases 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000008035 Back Pain Diseases 0.000 abstract 1
- 206010008479 Chest Pain Diseases 0.000 abstract 1
- 206010010774 Constipation Diseases 0.000 abstract 1
- 208000010201 Exanthema Diseases 0.000 abstract 1
- 206010019233 Headaches Diseases 0.000 abstract 1
- 206010060800 Hot flush Diseases 0.000 abstract 1
- 206010022998 Irritability Diseases 0.000 abstract 1
- 208000001089 Multiple system atrophy Diseases 0.000 abstract 1
- 206010028813 Nausea Diseases 0.000 abstract 1
- 206010029216 Nervousness Diseases 0.000 abstract 1
- 206010031127 Orthostatic hypotension Diseases 0.000 abstract 1
- 206010033557 Palpitations Diseases 0.000 abstract 1
- 206010033664 Panic attack Diseases 0.000 abstract 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 abstract 1
- 208000032140 Sleepiness Diseases 0.000 abstract 1
- 206010041349 Somnolence Diseases 0.000 abstract 1
- 206010046555 Urinary retention Diseases 0.000 abstract 1
- 208000012886 Vertigo Diseases 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 208000021017 Weight Gain Diseases 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 208000013219 diaphoresis Diseases 0.000 abstract 1
- 230000003292 diminished effect Effects 0.000 abstract 1
- 206010013781 dry mouth Diseases 0.000 abstract 1
- 201000006549 dyspepsia Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 201000005884 exanthem Diseases 0.000 abstract 1
- 206010016256 fatigue Diseases 0.000 abstract 1
- 231100000869 headache Toxicity 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 206010022437 insomnia Diseases 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 230000008693 nausea Effects 0.000 abstract 1
- 208000019906 panic disease Diseases 0.000 abstract 1
- 230000036470 plasma concentration Effects 0.000 abstract 1
- 206010037844 rash Diseases 0.000 abstract 1
- 208000019116 sleep disease Diseases 0.000 abstract 1
- 208000022925 sleep disturbance Diseases 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 230000035900 sweating Effects 0.000 abstract 1
- 231100000889 vertigo Toxicity 0.000 abstract 1
- 230000008673 vomiting Effects 0.000 abstract 1
- 230000004584 weight gain Effects 0.000 abstract 1
- 235000019786 weight gain Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42164002P | 2002-10-25 | 2002-10-25 | |
| US43162602P | 2002-12-05 | 2002-12-05 | |
| US43162702P | 2002-12-05 | 2002-12-05 | |
| US43186102P | 2002-12-09 | 2002-12-09 | |
| US43190602P | 2002-12-09 | 2002-12-09 | |
| US44361803P | 2003-01-29 | 2003-01-29 | |
| US45906103P | 2003-03-28 | 2003-03-28 | |
| US45899403P | 2003-03-28 | 2003-03-28 | |
| US45899503P | 2003-03-28 | 2003-03-28 | |
| PCT/US2003/033492 WO2004037190A2 (en) | 2002-10-25 | 2003-10-23 | Modified release compositions of milnacipran |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05004395A true MXPA05004395A (es) | 2006-02-10 |
Family
ID=32180880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05004395A MXPA05004395A (es) | 2002-10-25 | 2003-10-23 | Composiciones de milnacipran de liberacion modificada. |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20040132826A1 (https=) |
| EP (1) | EP1578403A4 (https=) |
| JP (1) | JP2006503918A (https=) |
| AU (1) | AU2003301671C1 (https=) |
| CA (1) | CA2503201C (https=) |
| MX (1) | MXPA05004395A (https=) |
| WO (1) | WO2004037190A2 (https=) |
Families Citing this family (125)
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|---|---|---|---|---|
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-
2003
- 2003-10-22 US US10/690,947 patent/US20040132826A1/en not_active Abandoned
- 2003-10-22 US US10/690,872 patent/US20040121010A1/en not_active Abandoned
- 2003-10-23 US US10/691,936 patent/US20040122104A1/en not_active Abandoned
- 2003-10-23 AU AU2003301671A patent/AU2003301671C1/en not_active Ceased
- 2003-10-23 EP EP03809613A patent/EP1578403A4/en not_active Withdrawn
- 2003-10-23 MX MXPA05004395A patent/MXPA05004395A/es active IP Right Grant
- 2003-10-23 JP JP2005501653A patent/JP2006503918A/ja active Pending
- 2003-10-23 CA CA2503201A patent/CA2503201C/en not_active Expired - Fee Related
- 2003-10-23 WO PCT/US2003/033492 patent/WO2004037190A2/en not_active Ceased
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|---|---|
| CA2503201A1 (en) | 2004-05-06 |
| WO2004037190A3 (en) | 2004-07-15 |
| JP2006503918A (ja) | 2006-02-02 |
| US20040132826A1 (en) | 2004-07-08 |
| US20040122104A1 (en) | 2004-06-24 |
| AU2003301671C1 (en) | 2006-08-17 |
| US20040121010A1 (en) | 2004-06-24 |
| EP1578403A4 (en) | 2007-01-03 |
| AU2003301671A1 (en) | 2004-05-13 |
| AU2003301671B2 (en) | 2006-02-09 |
| WO2004037190A2 (en) | 2004-05-06 |
| CA2503201C (en) | 2010-08-03 |
| EP1578403A2 (en) | 2005-09-28 |
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