MXPA04012656A - Anticuerpo hpam4 monoclonal humanizado. - Google Patents
Anticuerpo hpam4 monoclonal humanizado.Info
- Publication number
- MXPA04012656A MXPA04012656A MXPA04012656A MXPA04012656A MXPA04012656A MX PA04012656 A MXPA04012656 A MX PA04012656A MX PA04012656 A MXPA04012656 A MX PA04012656A MX PA04012656 A MXPA04012656 A MX PA04012656A MX PA04012656 A MXPA04012656 A MX PA04012656A
- Authority
- MX
- Mexico
- Prior art keywords
- antibody
- fragment
- pam4
- diagnostic
- agent
- Prior art date
Links
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Classifications
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- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1057—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from liver or pancreas
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- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
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- Immunology (AREA)
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- Endocrinology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38831402P | 2002-06-14 | 2002-06-14 | |
| PCT/GB2003/002593 WO2003106495A2 (en) | 2002-06-14 | 2003-06-16 | MONOCLONAL ANTIBODY hPAM4 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04012656A true MXPA04012656A (es) | 2005-08-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04012656A MXPA04012656A (es) | 2002-06-14 | 2003-06-16 | Anticuerpo hpam4 monoclonal humanizado. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7282567B2 (enExample) |
| EP (2) | EP1519958B1 (enExample) |
| JP (2) | JP5139626B2 (enExample) |
| KR (1) | KR101143035B1 (enExample) |
| CN (2) | CN1675245B (enExample) |
| AU (2) | AU2003277087B2 (enExample) |
| BR (1) | BR0311799A (enExample) |
| CA (1) | CA2489467C (enExample) |
| ES (1) | ES2524767T3 (enExample) |
| MX (1) | MXPA04012656A (enExample) |
| WO (1) | WO2003106495A2 (enExample) |
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| US7550143B2 (en) * | 2005-04-06 | 2009-06-23 | Ibc Pharmaceuticals, Inc. | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses |
| JP2005507659A (ja) * | 2001-10-15 | 2005-03-24 | イミューノメディクス、インコーポレイテッド | 直接ターゲッティング結合タンパク質 |
| US8491896B2 (en) * | 2002-06-14 | 2013-07-23 | Immunomedics, Inc. | Anti-pancreatic cancer antibodies |
| US7591994B2 (en) | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| US8877901B2 (en) | 2002-12-13 | 2014-11-04 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| US8435529B2 (en) | 2002-06-14 | 2013-05-07 | Immunomedics, Inc. | Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy |
| US20160279239A1 (en) | 2011-05-02 | 2016-09-29 | Immunomedics, Inc. | Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease |
| US9599619B2 (en) | 2002-06-14 | 2017-03-21 | Immunomedics, Inc. | Anti-pancreatic cancer antibodies |
| US9238081B2 (en) * | 2002-06-14 | 2016-01-19 | Immunomedics, Inc. | Detection of early-stage pancreatic adenocarcinoma |
| US8821868B2 (en) | 2002-06-14 | 2014-09-02 | Immunomedics, Inc. | Anti-pancreatic cancer antibodies |
| US9005613B2 (en) | 2003-06-16 | 2015-04-14 | Immunomedics, Inc. | Anti-mucin antibodies for early detection and treatment of pancreatic cancer |
| US7902338B2 (en) | 2003-07-31 | 2011-03-08 | Immunomedics, Inc. | Anti-CD19 antibodies |
| CA2595778A1 (en) * | 2005-01-28 | 2006-08-03 | Ramot At Tel Aviv University, Ltd. | Anti-muc1 .alpha..beta. antibodies |
| US20160355591A1 (en) | 2011-05-02 | 2016-12-08 | Immunomedics, Inc. | Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies |
| EP3332808B1 (en) | 2005-03-03 | 2020-09-09 | Immunomedics Inc. | Humanized l243 antibodies |
| JP2006248978A (ja) * | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
| DK1875244T3 (en) * | 2005-03-30 | 2019-04-29 | Minerva Biotechnologies Corp | Proliferation of MUC1-Expressing Cells |
| JP2008543276A (ja) * | 2005-03-30 | 2008-12-04 | ミネルバ バイオテクノロジーズ コーポレーション | Ｍｕｃ１発現細胞の増殖 |
| US20130039861A1 (en) * | 2005-04-06 | 2013-02-14 | Immunomedics, Inc. | Dye Conjugated Peptides for Fluorescent Imaging |
| EP2674440B1 (en) | 2005-12-16 | 2019-07-03 | IBC Pharmaceuticals, Inc. | Multivalent immunoglobulin-based bioactive assemblies |
| EP2623610B1 (en) * | 2006-02-10 | 2015-04-29 | Life Technologies Corporation | Labeling and detection of post translationally modified proteins |
| CA2647449C (en) * | 2006-03-27 | 2017-05-16 | Medimmune Limited | Binding member for gm-csf receptor |
| EP2083868A2 (en) * | 2006-10-04 | 2009-08-05 | Københavns Universitet | Generation of a cancer-specific immune response toward muc1 and cancer specific muc1 antibodies |
| US7777877B2 (en) * | 2006-10-20 | 2010-08-17 | California Institute Of Technology | High efficiency coupling optics for pumping and detection of fluorescence |
| JP5859202B2 (ja) * | 2007-05-21 | 2016-02-10 | アルダーバイオ・ホールディングズ・エルエルシー | 新規のウサギ抗体ヒト化方法及びヒト化ウサギ抗体 |
| US7906117B2 (en) | 2007-05-21 | 2011-03-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever |
| SI3187506T1 (sl) | 2007-05-21 | 2019-08-30 | Alderbio Holdings Llc | Protitelesa proti IL-6 in njihova uporaba |
| US9701747B2 (en) | 2007-05-21 | 2017-07-11 | Alderbio Holdings Llc | Method of improving patient survivability and quality of life by anti-IL-6 antibody administration |
| US8178101B2 (en) * | 2007-05-21 | 2012-05-15 | Alderbio Holdings Inc. | Use of anti-IL-6 antibodies having specific binding properties to treat cachexia |
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| CN101824090A (zh) | 2010-09-08 |
| CA2489467A1 (en) | 2003-12-24 |
| EP1519958A2 (en) | 2005-04-06 |
| EP2301968A2 (en) | 2011-03-30 |
| ES2524767T3 (es) | 2014-12-12 |
| AU2008212083B2 (en) | 2011-06-09 |
| US20080050311A1 (en) | 2008-02-28 |
| KR20050010054A (ko) | 2005-01-26 |
| US7282567B2 (en) | 2007-10-16 |
| CN101824090B (zh) | 2013-01-02 |
| JP5155356B2 (ja) | 2013-03-06 |
| US20050014207A1 (en) | 2005-01-20 |
| WO2003106495A3 (en) | 2004-04-01 |
| JP2006513695A (ja) | 2006-04-27 |
| AU2008212083A1 (en) | 2008-10-02 |
| CA2489467C (en) | 2015-02-24 |
| JP5139626B2 (ja) | 2013-02-06 |
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