MXPA04002490A - Interleucina-12 como adyuvante de vacuna veterinaria. - Google Patents
Interleucina-12 como adyuvante de vacuna veterinaria.Info
- Publication number
- MXPA04002490A MXPA04002490A MXPA04002490A MXPA04002490A MXPA04002490A MX PA04002490 A MXPA04002490 A MX PA04002490A MX PA04002490 A MXPA04002490 A MX PA04002490A MX PA04002490 A MXPA04002490 A MX PA04002490A MX PA04002490 A MXPA04002490 A MX PA04002490A
- Authority
- MX
- Mexico
- Prior art keywords
- immunogenicity
- enhancing
- composition
- immunoadjuvant
- immunomodulator
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Esta invencion describe una composicion para incrementar la inmunogenicidad de una vacuna veterinaria que comprende una cantidad farmacologicamente efectiva de un inmunorregulador y un inmunoadyuvante. Ademas, la descripcion describe una composicion de vacuna que comprende una un cantidad inmunizante efectiva de un antigeno, inmunorregulador, un inmunoadyuvante y un portador farmaceuticamente aceptable. Las composiciones pueden contener opcionalmente adyuvantes convencionales secundarios o conservadores. La invencion ademas describe un metodo unico para intensificar o acelerar la inmunogenicidad de antigenos marginalmente seguros, inmunosupresores o debiles al administrarle a una especie aviar o de mamifero, una cantidad farmacologicamente efectiva de la composicion intensificadora de la inmunogenicidad o una cantidad inmunizante efectiva de la composicion de vacuna anteriormente mencionada.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32284001P | 2001-09-17 | 2001-09-17 | |
US10/243,075 US20030129161A1 (en) | 2001-09-17 | 2002-09-12 | Interleukin-12 as a veterinary vaccine adjuvant |
PCT/US2002/029229 WO2003024354A2 (en) | 2001-09-17 | 2002-09-13 | Interleukin-12 as a veterinary vaccine adjuvant |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA04002490A true MXPA04002490A (es) | 2004-05-31 |
Family
ID=26935571
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA04002490A MXPA04002490A (es) | 2001-09-17 | 2002-09-13 | Interleucina-12 como adyuvante de vacuna veterinaria. |
Country Status (14)
Country | Link |
---|---|
US (2) | US20030129161A1 (es) |
EP (1) | EP1427349A4 (es) |
JP (1) | JP2005520786A (es) |
KR (1) | KR20040044942A (es) |
CN (1) | CN1555271A (es) |
BR (1) | BR0212556A (es) |
CA (1) | CA2457563A1 (es) |
HR (1) | HRP20040282A2 (es) |
HU (1) | HUP0500238A3 (es) |
MX (1) | MXPA04002490A (es) |
NZ (1) | NZ531526A (es) |
PL (1) | PL374123A1 (es) |
WO (1) | WO2003024354A2 (es) |
YU (1) | YU24004A (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7347996B1 (en) * | 2002-06-26 | 2008-03-25 | Intevert International B.V. | Avian cytokines, such as IL-12, comprising a p40 and/or p35 subunit and vaccines |
US20050089533A1 (en) * | 2003-01-29 | 2005-04-28 | Joseph Frantz | Canine vaccines against Bordetella bronchiseptica |
EP1708742A4 (en) * | 2003-12-05 | 2008-11-05 | Becton Dickinson Co | METHOD FOR IMPROVING THE IMMUNE RESPONSE IN THE INTRADERMAL COMPARTMENT AND USEFUL LINKS THEREFOR |
US20050202046A1 (en) * | 2004-03-11 | 2005-09-15 | Wyeth | Canine vaccine for protection against ehrlichiosis |
CN100425288C (zh) * | 2005-01-28 | 2008-10-15 | 北京金迪克生物技术研究所 | 鼻腔喷雾型流感病毒灭活疫苗及其制备方法 |
KR100517114B1 (ko) * | 2005-02-25 | 2005-09-27 | 주식회사 바이오리더스 | 폴리감마글루탐산을 함유하는 면역보강제 조성물 |
ATE499112T1 (de) | 2005-09-01 | 2011-03-15 | Celgene Corp | Immunologische verwendungen von immunmodulatorischen verbindungen für einen impfstoff und therapie gegen infektionskrankheiten |
US7682619B2 (en) * | 2006-04-06 | 2010-03-23 | Cornell Research Foundation, Inc. | Canine influenza virus |
AU2007343130C1 (en) | 2006-12-27 | 2017-11-09 | Zoetis Services Llc | Methods of vaccine administration |
KR100836745B1 (ko) * | 2007-01-31 | 2008-06-10 | (주)두비엘 | Hbv 백신 및 그의 제조 방법 |
CL2008001806A1 (es) * | 2007-06-20 | 2008-09-05 | Wyeth Corp | Composicion de vacuna en emulsion agua en aceite que comprende un antigeno y un adyuvante en la fase acuosa; y metodo de elaboracion. |
US8501190B2 (en) * | 2007-06-22 | 2013-08-06 | The University Of Guelph | Vaccine against Clostridium perfringens |
FR2922767B1 (fr) * | 2007-10-24 | 2009-12-18 | Seppic Sa | Procede de preparation d'une composition vaccinale comprenant au moins un antigene et au moins un adjuvant. |
ME01000B (me) | 2007-11-06 | 2012-10-20 | Zoetis Services Llc | Živa vakcina avirulentne mycoplasma hyopneumoniae sa adjuvansom |
US8273122B2 (en) | 2008-06-23 | 2012-09-25 | Abbott Medical Optics Inc. | Pre-loaded IOL insertion system |
CN105203755B (zh) | 2009-11-20 | 2018-01-05 | 爱贝斯股份有限公司 | 用于检测埃里希体属抗体的肽、装置和方法 |
CA2800348C (en) * | 2010-05-18 | 2020-07-21 | Lena A. Basile | Il-12 formulations for enhancing hematopoiesis |
CN102908613A (zh) * | 2011-08-04 | 2013-02-06 | 广州格拉姆生物科技有限公司 | 一种猪用免疫增强剂il-12b(p40)及其制备方法 |
JP6325553B2 (ja) | 2012-10-11 | 2018-05-16 | アバクシス, インコーポレイテッド | エールリヒア抗体の検出のためのペプチド、デバイス、および方法 |
CN103028114A (zh) * | 2012-12-28 | 2013-04-10 | 贵州大学 | 一种核酸疫苗、核酸疫苗免疫佐剂及制备方法 |
US9442112B2 (en) | 2014-04-04 | 2016-09-13 | Abaxis, Inc. | Compositions and methods for identifying Ehrlichia species |
CN104857511B (zh) * | 2015-02-13 | 2018-03-30 | 浙江大学 | 含人参皂甙的疫苗稀释剂 |
WO2017041720A1 (zh) * | 2015-09-09 | 2017-03-16 | 清华大学 | 作为高效的疫苗佐剂的甲羟戊酸通路的抑制剂 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5047238A (en) * | 1983-06-15 | 1991-09-10 | American Home Products Corporation | Adjuvants for vaccines |
US4567042A (en) * | 1983-06-15 | 1986-01-28 | American Home Products Corporation | Inactivated canine coronavirus vaccine |
US5503841A (en) * | 1985-09-20 | 1996-04-02 | Cetus Oncology Corporation | Human IL-2 as a vaccine adjuvant |
US5643565A (en) * | 1985-09-20 | 1997-07-01 | Chiron Corporation | Human IL-2 as a vaccine adjuvant |
US5266311A (en) * | 1987-05-28 | 1993-11-30 | Immunex Corporation | Bovine interleukin-1α |
US4894333A (en) * | 1987-05-28 | 1990-01-16 | Immunex Corporation | Bovine interleukin-1α |
US5106733A (en) * | 1987-06-25 | 1992-04-21 | Immunex Corporation | Bovine granulocyte-macrophage colony stimulating factor |
US5242686A (en) * | 1990-11-07 | 1993-09-07 | American Home Products Corporation | Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same |
US5593972A (en) * | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
US5571515A (en) * | 1994-04-18 | 1996-11-05 | The Wistar Institute Of Anatomy & Biology | Compositions and methods for use of IL-12 as an adjuvant |
MY111829A (en) * | 1994-05-10 | 2001-01-31 | Zoetis W Llc | Modified live brsv vaccine |
ES2257744T3 (es) * | 1994-10-05 | 2006-08-01 | Vanderbilt University | Interleuquina-12 como adyuvante para vacunas contra paramyxoviridae. |
US5674483A (en) * | 1995-01-31 | 1997-10-07 | National Jewish Medical And Research Center | Treatment for diseases involving inflammation |
US5665347A (en) * | 1995-02-02 | 1997-09-09 | Genetics Institute | IL-12 inhibition of B1 cell activity |
DE69620877T2 (de) * | 1995-02-06 | 2002-12-12 | Genetics Inst | Arzneimittelformulierungen für il-12 |
US5853714A (en) * | 1995-03-27 | 1998-12-29 | Genetics Institute, Inc. | Method for purification of IL-12 |
US5820869A (en) * | 1995-06-07 | 1998-10-13 | American Home Products Corporation | Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection |
US5972350A (en) * | 1996-05-06 | 1999-10-26 | Bayer Corporation | Feline vaccines containing Chlamydia psittaci and method for making the same |
ATE325621T1 (de) * | 1996-05-31 | 2006-06-15 | Nat Univ Ireland Maynooth | Il-12 als adjuvanz für bordetella pertussis impfstoffe |
GB9712347D0 (en) * | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
CA2243730C (en) * | 1997-07-29 | 2009-12-22 | Akzo Nobel N.V. | Streptococcus equi vaccine |
WO1999040937A2 (en) * | 1998-02-12 | 1999-08-19 | American Cyanamid Company | Vaccines comprising interleukin-12 and respiratory syncytial viral antigens |
US5985264A (en) * | 1998-03-05 | 1999-11-16 | The Medical College Of Ohio | IL-12 Stimulation of Neonatal immunity |
US6375944B1 (en) * | 1998-09-25 | 2002-04-23 | The Wistar Institute Of Anatomy And Biology | Methods and compositions for enhancing the immunostimulatory effect of interleukin-12 |
US6458942B1 (en) * | 1998-11-30 | 2002-10-01 | Research Development Foundation | 28-kDa immunoreactive protein gene of Ehrlichia canis and uses thereof |
AU6683400A (en) * | 1999-07-08 | 2001-01-30 | Mologen Forschungs-, Entwicklungs- Und Vertriebs Gmbh | Vaccine against lentiviral infections, such as the feline immune deficiency virus of the cat |
-
2002
- 2002-09-12 US US10/243,075 patent/US20030129161A1/en not_active Abandoned
- 2002-09-13 JP JP2003528254A patent/JP2005520786A/ja active Pending
- 2002-09-13 CN CNA028181964A patent/CN1555271A/zh active Pending
- 2002-09-13 YU YU24004A patent/YU24004A/sh unknown
- 2002-09-13 BR BRPI0212556-0A patent/BR0212556A/pt not_active IP Right Cessation
- 2002-09-13 HU HU0500238A patent/HUP0500238A3/hu unknown
- 2002-09-13 PL PL02374123A patent/PL374123A1/xx unknown
- 2002-09-13 KR KR10-2004-7003940A patent/KR20040044942A/ko not_active Application Discontinuation
- 2002-09-13 WO PCT/US2002/029229 patent/WO2003024354A2/en active Application Filing
- 2002-09-13 MX MXPA04002490A patent/MXPA04002490A/es not_active Application Discontinuation
- 2002-09-13 NZ NZ531526A patent/NZ531526A/en unknown
- 2002-09-13 EP EP02770517A patent/EP1427349A4/en not_active Withdrawn
- 2002-09-13 CA CA002457563A patent/CA2457563A1/en not_active Abandoned
-
2004
- 2004-03-22 HR HR20040282A patent/HRP20040282A2/hr not_active Application Discontinuation
-
2007
- 2007-08-03 US US11/890,063 patent/US20080003201A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HUP0500238A3 (en) | 2009-01-28 |
EP1427349A4 (en) | 2006-01-11 |
BR0212556A (pt) | 2007-04-17 |
WO2003024354A2 (en) | 2003-03-27 |
JP2005520786A (ja) | 2005-07-14 |
YU24004A (sh) | 2006-08-17 |
CA2457563A1 (en) | 2003-03-27 |
HUP0500238A2 (hu) | 2005-05-30 |
CN1555271A (zh) | 2004-12-15 |
EP1427349A2 (en) | 2004-06-16 |
US20080003201A1 (en) | 2008-01-03 |
WO2003024354A3 (en) | 2004-02-05 |
PL374123A1 (en) | 2005-10-03 |
HRP20040282A2 (en) | 2004-08-31 |
KR20040044942A (ko) | 2004-05-31 |
NZ531526A (en) | 2007-05-31 |
US20030129161A1 (en) | 2003-07-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |