MXPA02011883A - Un estuche de combinacion usado en el tratameinto de paludismo que contiene cloroquina y 3-(1-((4 -((6-metoxi-8 -quinolinil)amino) pentil) amino) -etilideno) -dihidro-2(3h) furanona. - Google Patents
Un estuche de combinacion usado en el tratameinto de paludismo que contiene cloroquina y 3-(1-((4 -((6-metoxi-8 -quinolinil)amino) pentil) amino) -etilideno) -dihidro-2(3h) furanona.Info
- Publication number
- MXPA02011883A MXPA02011883A MXPA02011883A MXPA02011883A MXPA02011883A MX PA02011883 A MXPA02011883 A MX PA02011883A MX PA02011883 A MXPA02011883 A MX PA02011883A MX PA02011883 A MXPA02011883 A MX PA02011883A MX PA02011883 A MXPA02011883 A MX PA02011883A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- amino
- combination kit
- days
- malaria
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 201000004792 malaria Diseases 0.000 title abstract 2
- 239000003430 antimalarial agent Substances 0.000 abstract 3
- ADCOUXIGWFEYJP-UHFFFAOYSA-N 3-[1-[4-[(6-methoxyquinolin-8-yl)amino]pentylamino]ethylidene]oxolan-2-one Chemical compound C=12N=CC=CC2=CC(OC)=CC=1NC(C)CCCNC(C)=C1CCOC1=O ADCOUXIGWFEYJP-UHFFFAOYSA-N 0.000 abstract 2
- 241000223810 Plasmodium vivax Species 0.000 abstract 2
- 239000002775 capsule Substances 0.000 abstract 2
- WHTVZRBIWZFKQO-AWEZNQCLSA-N (S)-chloroquine Chemical compound ClC1=CC=C2C(N[C@@H](C)CCCN(CC)CC)=CC=NC2=C1 WHTVZRBIWZFKQO-AWEZNQCLSA-N 0.000 abstract 1
- AEUAEICGCMSYCQ-UHFFFAOYSA-N 4-n-(7-chloroquinolin-1-ium-4-yl)-1-n,1-n-diethylpentane-1,4-diamine;dihydrogen phosphate Chemical compound OP(O)(O)=O.ClC1=CC=C2C(NC(C)CCCN(CC)CC)=CC=NC2=C1 AEUAEICGCMSYCQ-UHFFFAOYSA-N 0.000 abstract 1
- 229960003677 chloroquine Drugs 0.000 abstract 1
- WHTVZRBIWZFKQO-UHFFFAOYSA-N chloroquine Natural products ClC1=CC=C2C(NC(C)CCCN(CC)CC)=CC=NC2=C1 WHTVZRBIWZFKQO-UHFFFAOYSA-N 0.000 abstract 1
- 229960002328 chloroquine phosphate Drugs 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Un estuche de combinacion para el tratamiento del paludismo producido por Plasmodium vivax (P. vivax), que tiene dosis individuales de un agente antipaludico, 3-[1-[[4- [(6-metoxi -8-quinolinil) amino]pentil] amino] etilidenol-dihidro -2(3H) furanona (I) en forma de capsulas; dosis individuales del agente antipaludico, cloroquina en forma de comprimidos; y material de instruccion para la administracion de los dos farmacos antipaludicos. El estuche de combinacion es particularmente adecuado para un regimen de tratamiento de 6 dias, en el que el tratamiento se consigue mediante cinco comprimidos que contienen 500 mg de fosfato de cloroquina (equivalentes a 300 mg de base), debiendo tomarse tres el dia uno y uno cada uno de los dias dos y tres; y cinco capsulas que contienen 25 mg de 3-[1-[[4 -[(6-metoxi- 8-quinolinil) amino ]pentil] amino ]etilideno ]-dihidro -2(3H) -furanona (I), debiendo tomarse una cada uno de los dias dos a seis.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN501MU2000 | 2000-05-31 | ||
PCT/IN2000/000081 WO2001091535A2 (en) | 2000-05-31 | 2000-08-30 | A combination kit used in the treatment of malaria containing chloroquine and 3-(1-(((4-((6-methoxy-8-quinolinyl)amino)pentyl)amino)-ethylidene)-dihydro-2(3h)furanone enthält |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02011883A true MXPA02011883A (es) | 2004-05-17 |
Family
ID=11097250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02011883A MXPA02011883A (es) | 2000-05-31 | 2000-08-30 | Un estuche de combinacion usado en el tratameinto de paludismo que contiene cloroquina y 3-(1-((4 -((6-metoxi-8 -quinolinil)amino) pentil) amino) -etilideno) -dihidro-2(3h) furanona. |
Country Status (28)
Country | Link |
---|---|
US (1) | US7404962B1 (es) |
EP (1) | EP1292306B1 (es) |
JP (1) | JP2004505017A (es) |
KR (1) | KR20030025926A (es) |
AP (1) | AP1435A (es) |
AR (1) | AR028458A1 (es) |
AT (1) | ATE314848T1 (es) |
AU (2) | AU2001228790B2 (es) |
BR (1) | BR0005247A (es) |
CA (1) | CA2413775C (es) |
CR (1) | CR6835A (es) |
CZ (1) | CZ296875B6 (es) |
DE (2) | DE00993875T1 (es) |
DK (1) | DK1292306T3 (es) |
EC (1) | ECSP003694A (es) |
ES (1) | ES2200729T3 (es) |
GT (1) | GT200000187A (es) |
HK (1) | HK1052467B (es) |
HN (1) | HN2001000118A (es) |
HU (1) | HUP0301925A3 (es) |
MX (1) | MXPA02011883A (es) |
NO (1) | NO324774B1 (es) |
OA (1) | OA12276A (es) |
PE (1) | PE20011319A1 (es) |
PL (1) | PL200748B1 (es) |
SV (1) | SV2002000201A (es) |
WO (1) | WO2001091535A2 (es) |
ZA (1) | ZA200209726B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8114892B2 (en) * | 2006-02-16 | 2012-02-14 | The Mclean Hospital Corporation | Methods and compositions for the treatment of Parkinson's Disease |
WO2010065932A1 (en) * | 2008-12-05 | 2010-06-10 | Designmedix, Inc. | Modified chloroquines with single ring moiety or fused ring moiety |
WO2010144102A1 (en) * | 2009-06-09 | 2010-12-16 | The United States Of America, As Represented By The Secretary Of The Army, On Behalf Of U.S. Army Medical Research And Material Command | Pentafluorosulfanyl analogs of mefloquine |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4431807A (en) * | 1980-06-12 | 1984-02-14 | The United States Of America As Represented By The Secretary Of The Army | 4-Methyl-5-(unsubstituted and substituted phenoxy)-6-methoxy-8-(aminoalkylamino)quinolines |
US5219865A (en) * | 1987-05-08 | 1993-06-15 | Hoechst Aktiengesellschaft | Pharmaceutical combination for the prophylaxis and therapy of malaria |
US5373005A (en) * | 1988-04-20 | 1994-12-13 | Merrell Dow Pharmaceuticals Inc. | Despiramine in the treatment of drug-resistant malarial infections |
US5270037A (en) * | 1990-07-12 | 1993-12-14 | Boehringer Ingelheim Gmbh | Use of interferon and a substance with an antimalarial activity for the treatment of malaria infections |
JP3560970B2 (ja) * | 1992-02-07 | 2004-09-02 | ノバルティス アクチェンゲゼルシャフト | ベンゾフルメトールを含有する抗マラリア性の相乗作用組成物 |
-
2000
- 2000-08-30 US US10/296,215 patent/US7404962B1/en not_active Expired - Fee Related
- 2000-08-30 PL PL372718A patent/PL200748B1/pl not_active IP Right Cessation
- 2000-08-30 AU AU2001228790A patent/AU2001228790B2/en not_active Ceased
- 2000-08-30 KR KR1020027016169A patent/KR20030025926A/ko not_active Application Discontinuation
- 2000-08-30 DK DK00993875T patent/DK1292306T3/da active
- 2000-08-30 MX MXPA02011883A patent/MXPA02011883A/es active IP Right Grant
- 2000-08-30 DE DE0001292306T patent/DE00993875T1/de active Pending
- 2000-08-30 ES ES00993875T patent/ES2200729T3/es not_active Expired - Lifetime
- 2000-08-30 CA CA002413775A patent/CA2413775C/en not_active Expired - Fee Related
- 2000-08-30 JP JP2001587559A patent/JP2004505017A/ja active Pending
- 2000-08-30 AU AU2879001A patent/AU2879001A/xx active Pending
- 2000-08-30 WO PCT/IN2000/000081 patent/WO2001091535A2/en active IP Right Grant
- 2000-08-30 AP APAP/P/2002/002672A patent/AP1435A/en active
- 2000-08-30 DE DE60025403T patent/DE60025403T2/de not_active Expired - Lifetime
- 2000-08-30 HU HU0301925A patent/HUP0301925A3/hu unknown
- 2000-08-30 CZ CZ20024071A patent/CZ296875B6/cs not_active IP Right Cessation
- 2000-08-30 EP EP00993875A patent/EP1292306B1/en not_active Expired - Lifetime
- 2000-08-30 OA OA1200200359A patent/OA12276A/en unknown
- 2000-08-30 AT AT00993875T patent/ATE314848T1/de active
- 2000-10-05 EC EC2000003694A patent/ECSP003694A/es unknown
- 2000-10-13 SV SV2000000201A patent/SV2002000201A/es unknown
- 2000-10-25 GT GT200000187A patent/GT200000187A/es unknown
- 2000-11-06 BR BR0005247-7A patent/BR0005247A/pt not_active Application Discontinuation
-
2001
- 2001-05-14 AR ARP010102288A patent/AR028458A1/es unknown
- 2001-05-23 PE PE2001000469A patent/PE20011319A1/es not_active Application Discontinuation
- 2001-05-30 HN HN2001000118A patent/HN2001000118A/es unknown
-
2002
- 2002-11-28 CR CR6835A patent/CR6835A/es not_active Application Discontinuation
- 2002-11-29 NO NO20025765A patent/NO324774B1/no not_active IP Right Cessation
- 2002-11-29 ZA ZA200209726A patent/ZA200209726B/en unknown
-
2003
- 2003-07-07 HK HK03104811.6A patent/HK1052467B/zh not_active IP Right Cessation
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Legal Events
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FG | Grant or registration |