MX9806036A - Compuestos para inhibir tumores en el colon. - Google Patents

Compuestos para inhibir tumores en el colon.

Info

Publication number
MX9806036A
MX9806036A MX9806036A MX9806036A MX9806036A MX 9806036 A MX9806036 A MX 9806036A MX 9806036 A MX9806036 A MX 9806036A MX 9806036 A MX9806036 A MX 9806036A MX 9806036 A MX9806036 A MX 9806036A
Authority
MX
Mexico
Prior art keywords
methods
colon tumors
inhibiting colon
inhibiting
hexamethyleneimino
Prior art date
Application number
MX9806036A
Other languages
English (en)
Inventor
Maria Luisa Brandi
Francesco Tonelli
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603150.5A external-priority patent/GB9603150D0/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX9806036A publication Critical patent/MX9806036A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Un método para inhibir el cáncer de colon que comprende la administracion a un mamífero que necesita del mismo, una cantidad efectiva de un compuesto que tiene la formula (I, en donde R1 y R3 son independientemente hidrogeno, -CH3, (a), o (b), en donde Ar es fenilo opcionalmente sustituido; R2 se selecciona del grupo que consiste de pirrolidina, hexametilenimino y piperidino; o una sal farmacéuticamente aceptable o solvato del mismo.
MX9806036A 1996-01-29 1998-07-27 Compuestos para inhibir tumores en el colon. MX9806036A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1077296P 1996-01-29 1996-01-29
GBGB9603150.5A GB9603150D0 (en) 1996-02-15 1996-02-15 Methods of inhibiting colon tumors

Publications (1)

Publication Number Publication Date
MX9806036A true MX9806036A (es) 1998-11-29

Family

ID=26308709

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9806036A MX9806036A (es) 1996-01-29 1998-07-27 Compuestos para inhibir tumores en el colon.

Country Status (19)

Country Link
EP (1) EP0921799A4 (es)
JP (1) JP2000503994A (es)
KR (1) KR19990082054A (es)
CN (1) CN1209745A (es)
AR (1) AR010978A1 (es)
AU (1) AU707892B2 (es)
BR (1) BR9700778A (es)
CO (1) CO4761062A1 (es)
CZ (1) CZ235498A3 (es)
EA (1) EA001104B1 (es)
ID (1) ID15917A (es)
IL (1) IL125521A (es)
MX (1) MX9806036A (es)
NO (1) NO983451D0 (es)
NZ (1) NZ331105A (es)
PL (1) PL328147A1 (es)
TW (1) TW446560B (es)
WO (1) WO1997026877A1 (es)
YU (1) YU2397A (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
IL111287A0 (en) * 1993-10-15 1994-12-29 Lilly Co Eli Methods for treating resistant neoplasms
US5574047A (en) * 1993-12-21 1996-11-12 Eli Lilly And Company Methods of inhibiting imperfect tissue repair

Also Published As

Publication number Publication date
NO983451L (no) 1998-07-27
YU2397A (en) 1999-11-22
KR19990082054A (ko) 1999-11-15
EP0921799A4 (en) 2002-03-13
EP0921799A1 (en) 1999-06-16
CO4761062A1 (es) 1999-04-27
AR010978A1 (es) 2000-08-02
CN1209745A (zh) 1999-03-03
AU2123997A (en) 1997-08-20
JP2000503994A (ja) 2000-04-04
BR9700778A (pt) 1998-10-06
PL328147A1 (en) 1999-01-18
IL125521A0 (en) 1999-03-12
IL125521A (en) 2001-11-25
NO983451D0 (no) 1998-07-27
WO1997026877A1 (en) 1997-07-31
TW446560B (en) 2001-07-21
AU707892B2 (en) 1999-07-22
ID15917A (id) 1997-08-21
EA199800677A1 (ru) 1999-02-25
NZ331105A (en) 2000-06-23
EA001104B1 (ru) 2000-10-30
CZ235498A3 (cs) 1999-02-17

Similar Documents

Publication Publication Date Title
MY132251A (en) Methods of inhibiting cell-cell adhesion
MX9701329A (es) Metodos para la inhibicion de la replicacion viral.
MX9701325A (es) Metodos para inhibir la mucositis ulcerativa.
MX9701360A (es) Metodos para la inhibicion de la desmielinizacion y las enfermedades de la dismielinizacion.
DK0651999T3 (da) Fremgangsmåder til inhibering af livmoderfibrose
MX9709466A (es) Medicamento para inhibir el melanoma.
MX9701334A (es) Metodos para inhibir la degeneracion de protesis oseas.
MX9701327A (es) Metodos para inhibir el cancer endometrial.
MX9701333A (es) Metodos para inhibir el daño neuronal.
MX9702148A (es) Metodos para inhibir la mitosis endometrial.
MY113406A (en) Methods of inhibiting physiological conditions associated with an excess of bradykinin
MX9806036A (es) Compuestos para inhibir tumores en el colon.
MX9701359A (es) Metodos para la inhibicion de la hiperplasia endometrial primaria.
MX9706520A (es) Metodos para inhibir el cancer de ovario.
MX9705940A (es) Metodos y composiciones para inhibir los efectos de la interleucina 6.
MX9701331A (es) Metodos para mantener los dientes y los huesos bucales.
MX9701328A (es) Metodos de reduccion de la cicatrizacion en la curacion de heridas.
MX9709536A (es) Metodo para reducir el factor de transcripcion bef-1.
MX9702853A (es) Metodos para inhibir condiciones asociadas con el neuropeptido "y".
MX9709651A (es) Metodos para modulacion del factor de transcripcion nf-kb.
MX9705215A (es) Uso de 2-fenil-3-aroilbenzotiofenos para inhibir los efectos de la hormona del crecimiento.
MX9705537A (es) Metodos y composiciones para inhibir el efecto de los estrogenos del medio ambiente.
MX9705697A (es) Metodos para reducir los niveles de calcio del suero.