EA001104B1 - Способ ингибирования опухоли толстой кишки - Google Patents

Способ ингибирования опухоли толстой кишки Download PDF

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Publication number
EA001104B1
EA001104B1 EA199800677A EA199800677A EA001104B1 EA 001104 B1 EA001104 B1 EA 001104B1 EA 199800677 A EA199800677 A EA 199800677A EA 199800677 A EA199800677 A EA 199800677A EA 001104 B1 EA001104 B1 EA 001104B1
Authority
EA
Eurasian Patent Office
Prior art keywords
compound
cells
colon cancer
raloxifene
estrogen
Prior art date
Application number
EA199800677A
Other languages
English (en)
Russian (ru)
Other versions
EA199800677A1 (ru
Inventor
Мария Л. Брэнди
Франческо Тонелли
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603150.5A external-priority patent/GB9603150D0/en
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA199800677A1 publication Critical patent/EA199800677A1/ru
Publication of EA001104B1 publication Critical patent/EA001104B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
EA199800677A 1996-01-29 1997-01-27 Способ ингибирования опухоли толстой кишки EA001104B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1077296P 1996-01-29 1996-01-29
GBGB9603150.5A GB9603150D0 (en) 1996-02-15 1996-02-15 Methods of inhibiting colon tumors
PCT/US1997/002286 WO1997026877A1 (en) 1996-01-29 1997-01-27 Methods of inhibiting colon tumors

Publications (2)

Publication Number Publication Date
EA199800677A1 EA199800677A1 (ru) 1999-02-25
EA001104B1 true EA001104B1 (ru) 2000-10-30

Family

ID=26308709

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800677A EA001104B1 (ru) 1996-01-29 1997-01-27 Способ ингибирования опухоли толстой кишки

Country Status (19)

Country Link
EP (1) EP0921799A4 (es)
JP (1) JP2000503994A (es)
KR (1) KR19990082054A (es)
CN (1) CN1209745A (es)
AR (1) AR010978A1 (es)
AU (1) AU707892B2 (es)
BR (1) BR9700778A (es)
CO (1) CO4761062A1 (es)
CZ (1) CZ235498A3 (es)
EA (1) EA001104B1 (es)
ID (1) ID15917A (es)
IL (1) IL125521A (es)
MX (1) MX9806036A (es)
NO (1) NO983451L (es)
NZ (1) NZ331105A (es)
PL (1) PL328147A1 (es)
TW (1) TW446560B (es)
WO (1) WO1997026877A1 (es)
YU (1) YU2397A (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
ATE220323T1 (de) * 1993-10-15 2002-07-15 Lilly Co Eli Methode zur behandlung von resistenten neoplasmen
US5574047A (en) * 1993-12-21 1996-11-12 Eli Lilly And Company Methods of inhibiting imperfect tissue repair

Also Published As

Publication number Publication date
CO4761062A1 (es) 1999-04-27
AU707892B2 (en) 1999-07-22
ID15917A (id) 1997-08-21
IL125521A0 (en) 1999-03-12
CN1209745A (zh) 1999-03-03
JP2000503994A (ja) 2000-04-04
YU2397A (en) 1999-11-22
TW446560B (en) 2001-07-21
EP0921799A1 (en) 1999-06-16
MX9806036A (es) 1998-11-29
NO983451D0 (no) 1998-07-27
EA199800677A1 (ru) 1999-02-25
WO1997026877A1 (en) 1997-07-31
NO983451L (no) 1998-07-27
CZ235498A3 (cs) 1999-02-17
EP0921799A4 (en) 2002-03-13
BR9700778A (pt) 1998-10-06
IL125521A (en) 2001-11-25
KR19990082054A (ko) 1999-11-15
AR010978A1 (es) 2000-08-02
PL328147A1 (en) 1999-01-18
NZ331105A (en) 2000-06-23
AU2123997A (en) 1997-08-20

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU