MX9803692A - Derivados de eritromicina triciclicos. - Google Patents

Derivados de eritromicina triciclicos.

Info

Publication number
MX9803692A
MX9803692A MX9803692A MX9803692A MX9803692A MX 9803692 A MX9803692 A MX 9803692A MX 9803692 A MX9803692 A MX 9803692A MX 9803692 A MX9803692 A MX 9803692A MX 9803692 A MX9803692 A MX 9803692A
Authority
MX
Mexico
Prior art keywords
compounds
erythromycin derivatives
tricyclic
tricyclic erythromycin
antibacterial
Prior art date
Application number
MX9803692A
Other languages
English (en)
Inventor
Yat Sun Or
Ly Tam Phan
Daniel T Chu
Kenneth P Spina
Robert Hallas
Richard L Elliott
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX9803692A publication Critical patent/MX9803692A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Compuestos, o sales farmacéuticamente aceptables y ésteres de los mismos, de las formulas (I); (II); (III) o (IV), en donde A, B, D, y E, R1, R2, y Z se definen específicamente, que tienen actividad antibacteriana; composiciones farmacéuticas que contienen a estos compuestos; tratamiento de infecciones antibacterianos con dichas composiciones, y procesos para la preparacion de los compuestos.
MX9803692A 1995-11-08 1998-05-08 Derivados de eritromicina triciclicos. MX9803692A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55524695A 1995-11-08 1995-11-08

Publications (1)

Publication Number Publication Date
MX9803692A true MX9803692A (es) 1998-09-30

Family

ID=24216555

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9803692A MX9803692A (es) 1995-11-08 1998-05-08 Derivados de eritromicina triciclicos.

Country Status (12)

Country Link
EP (1) EP0876388B1 (es)
JP (1) JP2000500133A (es)
KR (1) KR19990067492A (es)
AT (1) ATE259823T1 (es)
AU (1) AU7447096A (es)
DE (1) DE69631609T2 (es)
DK (1) DK0876388T3 (es)
ES (1) ES2218604T3 (es)
IL (1) IL123551A0 (es)
MX (1) MX9803692A (es)
PT (1) PT876388E (es)
WO (1) WO1997017356A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274715B1 (en) * 1995-11-08 2001-08-14 Abbott Laboratories Tricyclic erythromycin derivatives
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
IL128681A0 (en) * 1996-09-04 2000-01-31 Abbott Lab 6-O substituted ketolides having antibacterial activity
NZ500531A (en) * 1997-05-29 2001-07-27 Abbott Lab Multicyclic erythromycin derivatives having antibacterial activity
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
ZA987689B (en) * 1997-09-02 1999-02-24 Abbott Lab 3-descladinose 6-O substituted erythromycin derivatives
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
HUP0004579A3 (en) * 1997-09-30 2001-11-28 Abbott Lab 3'-n-modified 6-0-substituted erythromycin ketolide derivatives having antibacterial activity and pharmaceutical compositions comprising them
PA8461401A1 (es) 1997-10-29 2000-05-24 Pfizer Prod Inc Derivados de eritromicina triciclicos
US6046171A (en) * 1997-10-29 2000-04-04 Abbott Laboratories 6,11-bridged erythromycin derivatives
AR015986A1 (es) * 1997-10-29 2001-05-30 Abbott Lab Derivados de eritromicina puenteados en 6,11, composiciones farmaceuticas que los contienen, su uso para la manufactura de un medicamento y procedimientospara su preparacion
US6124269A (en) * 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
DK0952157T3 (da) 1998-04-24 2003-10-13 Pfizer Prod Inc 9a, 11b-dehydroderivater af 9-oxim-3-keto-6-0-methylerythromycin
US6248719B1 (en) 1998-06-03 2001-06-19 Pfizer Inc Tricyclic 3-keto derivatives of 6-O-methylerthromycin
FR2780977B1 (fr) * 1998-07-09 2000-09-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
US6472372B1 (en) * 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
WO2003024986A1 (en) 2001-09-17 2003-03-27 Ortho-Mcneil Pharmaceutical, Inc. 6-o-carbamate-11,12-lacto-ketolide antimicrobials
NZ533282A (en) 2001-12-05 2006-09-29 Ortho Mcneil Pharm Inc 6-O-Acyl ketolide derivatives of erythromycine useful as antibacterials
CA2487918A1 (en) * 2002-05-31 2003-12-11 Janssen Pharmaceutica N.V. 3-descladinosyl-6-o-carbamoyl and 6-o-carbonoyl macrolide antibacterial agents
ES2331867B1 (es) 2008-07-17 2010-10-27 Entrechem, S.L. Sintesis enzimatica de derivados enantiomericamente enriquecidos de trans-ciclopentano- 1,2-diaminas.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0166096B1 (ko) * 1990-11-28 1999-01-15 우에하라 아키라 6-0-메틸에리쓰로마이신 a 유도체
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
DK0638584T3 (da) * 1992-04-22 1996-04-15 Taisho Pharmaceutical Co Ltd 5-O-desosaminyl-erythronolid-A-derivat

Also Published As

Publication number Publication date
DK0876388T3 (da) 2004-06-07
IL123551A0 (en) 1998-10-30
ES2218604T3 (es) 2004-11-16
JP2000500133A (ja) 2000-01-11
PT876388E (pt) 2004-07-30
AU7447096A (en) 1997-05-29
DE69631609T2 (de) 2005-01-05
ATE259823T1 (de) 2004-03-15
WO1997017356A1 (en) 1997-05-15
DE69631609D1 (en) 2004-03-25
EP0876388A1 (en) 1998-11-11
KR19990067492A (ko) 1999-08-25
EP0876388B1 (en) 2004-02-18

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees