UA29435C2 - Похідні 3бета-алкенілпенаму та їх фармацевтично прийнятні солі - Google Patents

Похідні 3бета-алкенілпенаму та їх фармацевтично прийнятні солі

Info

Publication number
UA29435C2
UA29435C2 UA94085740A UA94085740A UA29435C2 UA 29435 C2 UA29435 C2 UA 29435C2 UA 94085740 A UA94085740 A UA 94085740A UA 94085740 A UA94085740 A UA 94085740A UA 29435 C2 UA29435 C2 UA 29435C2
Authority
UA
Ukraine
Prior art keywords
font
alkenylpenam
derivatives
symbol
compatible salts
Prior art date
Application number
UA94085740A
Other languages
English (en)
Russian (ru)
Inventor
Крістіан Хубшверлен
Кристиан ХУБШВЕРЛЕН
Ганс Ріхтер
Ганс Рихтер
Жан-Люк Спеклін
Жан-Люк Спеклин
Original Assignee
Ф.Хоффманн-Ля Рош Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ф.Хоффманн-Ля Рош Аг filed Critical Ф.Хоффманн-Ля Рош Аг
Publication of UA29435C2 publication Critical patent/UA29435C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Об'єктом даного винаходу є похідні 3 β-алкенілпенаму і їхні фармацевтично сумісні солі як такі і як фармацевтично активні речовини, приготування цих сполук. Винахід стосується також лікарських засобів, що містять ці сполуки і, за певних умов, додатково О-лактамовий антибіотик.
UA94085740A 1993-08-24 1994-08-23 Похідні 3бета-алкенілпенаму та їх фармацевтично прийнятні солі UA29435C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH251193 1993-08-24
CH168794 1994-05-31

Publications (1)

Publication Number Publication Date
UA29435C2 true UA29435C2 (uk) 2000-11-15

Family

ID=25688383

Family Applications (1)

Application Number Title Priority Date Filing Date
UA94085740A UA29435C2 (uk) 1993-08-24 1994-08-23 Похідні 3бета-алкенілпенаму та їх фармацевтично прийнятні солі

Country Status (22)

Country Link
US (2) US5637579A (uk)
EP (1) EP0640607B1 (uk)
JP (1) JP2642314B2 (uk)
KR (1) KR100362294B1 (uk)
CN (1) CN1067078C (uk)
AT (1) ATE148705T1 (uk)
AU (1) AU674768B2 (uk)
CA (1) CA2129564C (uk)
CZ (1) CZ203994A3 (uk)
DE (1) DE59401750D1 (uk)
DK (1) DK0640607T3 (uk)
ES (1) ES2097589T3 (uk)
FI (1) FI113775B (uk)
GR (1) GR3023228T3 (uk)
HU (1) HUT67880A (uk)
IL (1) IL110711A (uk)
NO (1) NO307054B1 (uk)
NZ (1) NZ264272A (uk)
RU (1) RU2139290C1 (uk)
SG (1) SG48064A1 (uk)
TW (1) TW383308B (uk)
UA (1) UA29435C2 (uk)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686441A (en) * 1995-08-04 1997-11-11 Syphar Laboratories, Inc. Penam sulfones as β-lactamase inhibitors
US6150350A (en) * 1997-09-15 2000-11-21 Hoffman-La Roche Inc. Antimicrobial compositions
US6156745A (en) 1997-12-29 2000-12-05 Research Corporation Technologies, Inc. 2β-substituted-6-alkylidene penicillanic acid derivatives as β-lactamase inhibitors
CA2341650A1 (en) * 1998-09-01 2000-03-09 Merck & Co., Inc. Carbapenem antibacterial compositions and methods of treatment
JP2002535335A (ja) * 1999-01-26 2002-10-22 アメリカン・サイアナミド・カンパニー 抗菌剤としての３，６−二置換ペナムスルホン誘導体
US6395726B1 (en) 1999-01-26 2002-05-28 American Cyanamid Company 3,6-disubstituted penam sulfone derivatives
US6407091B1 (en) 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
US6221859B1 (en) 1999-08-27 2001-04-24 Merck & Co., Inc. Carbapenem antibacterial compositions and methods of the treatment
WO2002022137A1 (en) * 2000-09-12 2002-03-21 Shoichet Brian K β-LACTAM ANALOGS AND USES THEREFOR
CN1479906A (zh) * 2000-10-11 2004-03-03 用于健康护理数据的通信的系统
US6916801B2 (en) 2001-07-24 2005-07-12 Alamx, Llc 7-Alkylidene-3-substituted-3-cephem-4-carboxylates as β-lactamase inhibitors
JP2005525399A (ja) 2002-04-04 2005-08-25 アラムクス エルエルシー セリンおよびメタロ−β−ラクタマーゼの阻害剤
CN103724330B (zh) 2005-12-07 2015-08-19 巴斯利尔药物股份公司 单环-内酰胺类抗生素与β-内酰胺酶抑制剂的有效的联合应用
AU2012233003B2 (en) * 2005-12-07 2014-12-18 Basilea Pharmaceutica Ag Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
WO2018015278A1 (en) 2016-07-21 2018-01-25 Unilever Plc Lactams for use in the treatment of skin lesions
BR112019001134A2 (pt) 2016-07-21 2019-04-30 Unilever N.V. uso de lactama e composição farmacêutica
EP3487496A1 (en) 2016-07-21 2019-05-29 Unilever PLC 4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one for use in the treatment of gram negative bacterial infections
US20200230114A1 (en) * 2019-01-22 2020-07-23 Board Of Regents Of The Nevada System Of Higher Education On Behalf Of Nevada The use of lipophilic beta-lactam antibiotics and carboxylate esters for the treatment of bacterial infections within citrus and other plant species

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT365594B (de) * 1978-11-24 1982-01-25 Erba Farmitalia Verfahren zur herstellung von neuen 7-oxo-4-thia1-aza-bicyclo-(3,2,0)heptanderivaten
US4282236A (en) * 1979-11-07 1981-08-04 Beecham Group Limited β-Lactam antibacterial agents, their use in pharmaceutical compositions, and intermediates
US4365174A (en) * 1980-07-31 1982-12-21 Rca Corporation Pulse counter type circuit for power-up indication
ZA826687B (en) * 1981-09-14 1983-07-27 Pfizer Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl 5(r)penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor
GB8509180D0 (en) * 1985-04-10 1985-05-15 Erba Farmitalia Penem derivatives
US4861768A (en) * 1986-02-27 1989-08-29 Taiho Pharmaceutical Company, Limited 2 β-substituted thiomethylpenicillin derivatives and their preparation and use
US4891369A (en) * 1986-12-03 1990-01-02 Taiho Pharmaceutical Company, Limited 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof
US5132300A (en) * 1989-06-01 1992-07-21 Pfizer Inc. Beta-lactam elastase inhibitors

Also Published As

Publication number Publication date
RU2139290C1 (ru) 1999-10-10
HU9402391D0 (en) 1994-10-28
KR950005830A (ko) 1995-03-20
US5644053A (en) 1997-07-01
CN1067078C (zh) 2001-06-13
CN1106408A (zh) 1995-08-09
CA2129564A1 (en) 1995-02-25
JP2642314B2 (ja) 1997-08-20
NZ264272A (en) 1996-10-28
FI943885A (fi) 1995-02-25
IL110711A0 (en) 1994-11-11
HUT67880A (en) 1995-05-29
EP0640607A1 (de) 1995-03-01
JPH0782273A (ja) 1995-03-28
NO943104D0 (no) 1994-08-23
ES2097589T3 (es) 1997-04-01
TW383308B (en) 2000-03-01
DK0640607T3 (da) 1997-06-16
ATE148705T1 (de) 1997-02-15
FI113775B (fi) 2004-06-15
RU94030236A (ru) 1996-06-20
KR100362294B1 (ko) 2005-08-25
FI943885A0 (fi) 1994-08-24
GR3023228T3 (en) 1997-07-30
DE59401750D1 (de) 1997-03-20
EP0640607B1 (de) 1997-02-05
NO943104L (no) 1995-02-27
AU674768B2 (en) 1997-01-09
CZ203994A3 (en) 1995-03-15
AU7035694A (en) 1995-03-09
CA2129564C (en) 2006-07-25
IL110711A (en) 1999-08-17
US5637579A (en) 1997-06-10
SG48064A1 (en) 1998-04-17
NO307054B1 (no) 2000-01-31

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