MX9709669A - Peptido mejorado, composicion inmunogenica y vacuna o preparacion medica, metodo para inmunizar animales contra la hormona lhrh y analogos del peptido lhrh repetido en tandem y su uso como vacuna. - Google Patents
Peptido mejorado, composicion inmunogenica y vacuna o preparacion medica, metodo para inmunizar animales contra la hormona lhrh y analogos del peptido lhrh repetido en tandem y su uso como vacuna.Info
- Publication number
- MX9709669A MX9709669A MX9709669A MX9709669A MX9709669A MX 9709669 A MX9709669 A MX 9709669A MX 9709669 A MX9709669 A MX 9709669A MX 9709669 A MX9709669 A MX 9709669A MX 9709669 A MX9709669 A MX 9709669A
- Authority
- MX
- Mexico
- Prior art keywords
- lhrh
- vaccine
- peptide
- tandem
- hormone
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 241001465754 Metazoa Species 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 2
- 229940088597 hormone Drugs 0.000 title 1
- 239000005556 hormone Substances 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
- 239000000579 Gonadotropin-Releasing Hormone Substances 0.000 abstract 5
- 108700012941 GNRH1 Proteins 0.000 abstract 3
- 101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 abstract 2
- XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 abstract 2
- 229940035638 gonadotropin-releasing hormone Drugs 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000539 dimer Substances 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 229940023041 peptide vaccine Drugs 0.000 abstract 1
- 230000001850 reproductive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invencion se refiere a una preparacion de vacuna con un péptido LHRH en tándem modificado, en el cual el aminoácido glicina en la posicion (6) de uno o ambos decapéptidos de LHRH que constituyen la unidad en tándem , es (son) sustituido(s) por un aminoácido dextrorrotatorio que contiene una cadena lateral a la cual se puede acoplar un compuesto acarreador. Además, el péptido LHRH en támdem se puede preparar en una forma tándem-dímero, la cual también es adecuada para producir una vacuna efectiva contra la LHRH (hormona liberadora de la homona luteinizante), también referida como GnRH (hormona liberadora de gonadotropina), en general para castracion inmunologica, para inhibir o afectar funciones del comportamiento en vertebrados y en particular en animales domésticos y en seres humanos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47729895A | 1995-06-07 | 1995-06-07 | |
US47601395A | 1995-06-07 | 1995-06-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9709669A true MX9709669A (es) | 1998-10-31 |
Family
ID=27045028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9709669A MX9709669A (es) | 1995-06-07 | 1997-12-05 | Peptido mejorado, composicion inmunogenica y vacuna o preparacion medica, metodo para inmunizar animales contra la hormona lhrh y analogos del peptido lhrh repetido en tandem y su uso como vacuna. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0832107B1 (es) |
JP (1) | JP3959746B2 (es) |
KR (1) | KR100335320B1 (es) |
CN (1) | CN1159338C (es) |
AT (1) | ATE205219T1 (es) |
AU (1) | AU710778B2 (es) |
BR (2) | BRPI9609411B8 (es) |
CA (1) | CA2221129C (es) |
DE (1) | DE69615026T2 (es) |
DK (1) | DK0832107T3 (es) |
ES (1) | ES2163631T3 (es) |
HK (1) | HK1014963A1 (es) |
HU (1) | HU226293B1 (es) |
MX (1) | MX9709669A (es) |
RU (1) | RU2147307C1 (es) |
WO (1) | WO1996040755A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6761890B1 (en) | 1995-06-07 | 2004-07-13 | Pepscan Systems B.V. | Peptide, immunogenic composition and vaccine or medical preparation, a method to immunize animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine |
AUPO776897A0 (en) | 1997-07-09 | 1997-07-31 | Csl Limited | A method of achieving production gains in livestock and agents useful for same |
US6013770A (en) * | 1997-07-21 | 2000-01-11 | Washington State University | Chimeric contraceptive vaccines |
US8709998B2 (en) | 2003-04-22 | 2014-04-29 | Ipsen Pharma S.A.S. | Peptide vectors |
GB0329146D0 (en) * | 2003-12-16 | 2004-01-21 | Glaxosmithkline Biolog Sa | Vaccine |
WO2007093373A2 (en) * | 2006-02-14 | 2007-08-23 | Università Degli Studi Di Siena | Branched multimeric peptides for tumor diagnosis and therapy |
AT508569A1 (de) * | 2009-07-23 | 2011-02-15 | Affiris Ag | Pharmaceutical compound |
TWI418362B (zh) * | 2010-11-19 | 2013-12-11 | Univ Nat Pingtung Sci & Tech | 溶血性巴斯德桿菌重組外膜脂蛋白e及含此之疫苗組成物 |
EP2703483A1 (en) | 2012-08-29 | 2014-03-05 | Affiris AG | PCSK9 peptide vaccine |
ITBO20130129A1 (it) * | 2013-03-27 | 2014-09-28 | Gd Spa | Articolo da fumo |
CN103554228B (zh) * | 2013-11-11 | 2016-05-04 | 宁波市三生药业有限公司 | 一种GnRH去势疫苗及并列体 |
RU2745720C2 (ru) * | 2014-07-25 | 2021-03-31 | Юнайтед Байомедикал, Инк. | Иммуногенная композиция lhrh и ее применение у свиней |
CN107449924B (zh) * | 2017-10-12 | 2019-03-19 | 华派生物工程集团有限公司 | 一种鸡免疫去势效果的判定方法 |
BR102018068504A2 (pt) * | 2018-09-12 | 2021-11-16 | Ouro Fino Saúde Animal Ltda | Polipeptídeo quimérico antigênico, construção gênica e composição antigênica para imunocastração de mamíferos não humanos |
KR102477054B1 (ko) * | 2020-03-24 | 2022-12-14 | 주식회사 바이오앱 | 웅취 제거용 재조합 단백질 및 이를 포함하는 백신 조성물 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8713240D0 (en) * | 1987-06-05 | 1987-07-08 | Proteus Biotech Ltd | Hormones |
NL8900726A (nl) * | 1989-03-23 | 1990-10-16 | Stichting Centr Diergeneeskund | Peptide, immunogene samenstelling en vaccin- of geneesmiddelpreparaat; werkwijze voor het immuniseren van een zoogdier tegen lhrh, en werkwijze voor het verbeteren van de vleeskwaliteit van varkens. |
GB2282813A (en) * | 1993-10-15 | 1995-04-19 | Merck & Co Inc | Annular antigen scaffolds comprising thioether linkages |
-
1996
- 1996-06-06 KR KR1019970709019A patent/KR100335320B1/ko not_active IP Right Cessation
- 1996-06-06 WO PCT/NL1996/000223 patent/WO1996040755A1/en active IP Right Grant
- 1996-06-06 EP EP96916372A patent/EP0832107B1/en not_active Expired - Lifetime
- 1996-06-06 BR BRPI9609411A patent/BRPI9609411B8/pt unknown
- 1996-06-06 RU RU98100226A patent/RU2147307C1/ru active
- 1996-06-06 CA CA002221129A patent/CA2221129C/en not_active Expired - Lifetime
- 1996-06-06 CN CNB961946091A patent/CN1159338C/zh not_active Expired - Lifetime
- 1996-06-06 JP JP50032397A patent/JP3959746B2/ja not_active Expired - Fee Related
- 1996-06-06 HU HU0001431A patent/HU226293B1/hu unknown
- 1996-06-06 AU AU59130/96A patent/AU710778B2/en not_active Expired
- 1996-06-06 DK DK96916372T patent/DK0832107T3/da active
- 1996-06-06 BR BR9609411-7A patent/BR9609411A/pt active IP Right Grant
- 1996-06-06 DE DE69615026T patent/DE69615026T2/de not_active Expired - Lifetime
- 1996-06-06 ES ES96916372T patent/ES2163631T3/es not_active Expired - Lifetime
- 1996-06-06 AT AT96916372T patent/ATE205219T1/de active
-
1997
- 1997-12-05 MX MX9709669A patent/MX9709669A/es unknown
-
1999
- 1999-01-07 HK HK99100064A patent/HK1014963A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0832107B1 (en) | 2001-09-05 |
KR19990022538A (ko) | 1999-03-25 |
JP3959746B2 (ja) | 2007-08-15 |
HK1014963A1 (en) | 1999-10-08 |
AU5913096A (en) | 1996-12-30 |
BRPI9609411B8 (pt) | 2020-05-12 |
BR9609411A (pt) | 1999-12-14 |
ES2163631T3 (es) | 2002-02-01 |
JP2002504886A (ja) | 2002-02-12 |
ATE205219T1 (de) | 2001-09-15 |
CA2221129C (en) | 2002-09-17 |
CA2221129A1 (en) | 1996-12-19 |
HUP0001431A2 (hu) | 2001-02-28 |
EP0832107A1 (en) | 1998-04-01 |
DE69615026T2 (de) | 2002-02-14 |
CN1159338C (zh) | 2004-07-28 |
CN1187200A (zh) | 1998-07-08 |
WO1996040755A1 (en) | 1996-12-19 |
DK0832107T3 (da) | 2001-11-19 |
HUP0001431A3 (en) | 2001-09-28 |
DE69615026D1 (de) | 2001-10-11 |
KR100335320B1 (ko) | 2002-09-13 |
AU710778B2 (en) | 1999-09-30 |
RU2147307C1 (ru) | 2000-04-10 |
HU226293B1 (en) | 2008-08-28 |
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