MX9701856A - Preparacion de liposomas multi-vesiculares para la liberacion controlada de agentes activos. - Google Patents
Preparacion de liposomas multi-vesiculares para la liberacion controlada de agentes activos.Info
- Publication number
- MX9701856A MX9701856A MX9701856A MX9701856A MX9701856A MX 9701856 A MX9701856 A MX 9701856A MX 9701856 A MX9701856 A MX 9701856A MX 9701856 A MX9701856 A MX 9701856A MX 9701856 A MX9701856 A MX 9701856A
- Authority
- MX
- Mexico
- Prior art keywords
- liposomes
- multivesicular liposomes
- active substance
- biologically active
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
Abstract
Se divulgan liposomas multi-vasiculares (MVLs) que contienen sustancias biologicamente activas, los liposomas multivesiculares teniendo distribucion de tamaños definida, tamaño promedio ajustable, tamaño y numero ajustable de cámaras internas, y una tasa de liberacion controlada y variable de la sustancia biologicamente activa. El proceso implica encapsular al menos una sustancia biologicamente activa y opcionalmente un separador osmotico en un primer componente acuoso encapsulado dentro de los liposomas. La tasa de liberacion de la sustancia activa hacia el ambiente circundante en el que se introducen los liposomas puede ser reducida incrementando la osmolaridad del primer componente acuoso o incrementada reduciendo la osmolaridad.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/305,158 US5993850A (en) | 1994-09-13 | 1994-09-13 | Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9701856A true MX9701856A (es) | 1998-07-31 |
Family
ID=23179585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9701856A MX9701856A (es) | 1994-09-13 | 1997-03-12 | Preparacion de liposomas multi-vesiculares para la liberacion controlada de agentes activos. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5993850A (es) |
EP (1) | EP0781123B1 (es) |
JP (1) | JP3026271B2 (es) |
KR (1) | KR100387561B1 (es) |
CN (1) | CN1096850C (es) |
AU (1) | AU697484B2 (es) |
BR (1) | BR9508913A (es) |
CA (1) | CA2199004C (es) |
DE (1) | DE69535297T2 (es) |
FI (1) | FI119621B (es) |
MX (1) | MX9701856A (es) |
NO (1) | NO323581B1 (es) |
NZ (2) | NZ334561A (es) |
WO (1) | WO1996008235A1 (es) |
Families Citing this family (73)
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US5891467A (en) * | 1997-01-31 | 1999-04-06 | Depotech Corporation | Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes |
KR19980067138A (ko) * | 1997-01-31 | 1998-10-15 | 박원훈 | 유전자 또는 생물학적 활성 약물을 세포내로 효과적으로 전달하는 지방 유제 및 그것의 제조방법 |
US6106858A (en) * | 1997-09-08 | 2000-08-22 | Skyepharma, Inc. | Modulation of drug loading in multivescular liposomes |
US6306432B1 (en) * | 1997-09-08 | 2001-10-23 | Chiron Corporation | High and low load formulations of IGF-I in multivesicular liposomes |
ATE535232T1 (de) | 1997-09-18 | 2011-12-15 | Pacira Pharmaceuticals Inc | Retardierte freisetzung liposomaler anesthetischer zusammensetzungen |
IL135989A0 (en) | 1997-11-14 | 2001-05-20 | Skyepharma Inc | Processes for the production of multivesicular liposomes |
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US20040037818A1 (en) * | 1998-07-30 | 2004-02-26 | Brand Stephen J. | Treatment for diabetes |
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JP6402097B2 (ja) | 2012-05-21 | 2018-10-10 | インスメッド インコーポレイテッド | 肺感染症を処置するためのシステム |
CN102764456B (zh) * | 2012-07-24 | 2014-10-15 | 上海交通大学 | 血管栓塞剂及其用途、制备方法 |
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-
1994
- 1994-09-13 US US08/305,158 patent/US5993850A/en not_active Expired - Lifetime
-
1995
- 1995-09-13 DE DE69535297T patent/DE69535297T2/de not_active Expired - Lifetime
- 1995-09-13 KR KR1019970701650A patent/KR100387561B1/ko not_active IP Right Cessation
- 1995-09-13 CN CN95196186A patent/CN1096850C/zh not_active Expired - Fee Related
- 1995-09-13 AU AU35115/95A patent/AU697484B2/en not_active Ceased
- 1995-09-13 CA CA002199004A patent/CA2199004C/en not_active Expired - Lifetime
- 1995-09-13 NZ NZ334561A patent/NZ334561A/xx not_active IP Right Cessation
- 1995-09-13 BR BR9508913A patent/BR9508913A/pt not_active IP Right Cessation
- 1995-09-13 WO PCT/US1995/011609 patent/WO1996008235A1/en active IP Right Grant
- 1995-09-13 NZ NZ292830A patent/NZ292830A/en not_active IP Right Cessation
- 1995-09-13 EP EP95931820A patent/EP0781123B1/en not_active Expired - Lifetime
- 1995-09-13 JP JP8510312A patent/JP3026271B2/ja not_active Expired - Fee Related
-
1997
- 1997-03-12 FI FI971037A patent/FI119621B/fi active
- 1997-03-12 NO NO19971149A patent/NO323581B1/no not_active IP Right Cessation
- 1997-03-12 MX MX9701856A patent/MX9701856A/es unknown
Also Published As
Publication number | Publication date |
---|---|
DE69535297T2 (de) | 2007-05-16 |
CA2199004C (en) | 2008-02-19 |
AU697484B2 (en) | 1998-10-08 |
NO971149D0 (no) | 1997-03-12 |
KR100387561B1 (ko) | 2003-10-08 |
JP3026271B2 (ja) | 2000-03-27 |
EP0781123B1 (en) | 2006-11-15 |
FI971037A0 (fi) | 1997-03-12 |
WO1996008235A1 (en) | 1996-03-21 |
AU3511595A (en) | 1996-03-29 |
BR9508913A (pt) | 1997-12-30 |
NO323581B1 (no) | 2007-06-11 |
NZ292830A (en) | 1999-04-29 |
US5993850A (en) | 1999-11-30 |
FI119621B (fi) | 2009-01-30 |
FI971037A (fi) | 1997-05-12 |
JPH10502667A (ja) | 1998-03-10 |
DE69535297D1 (de) | 2006-12-28 |
CA2199004A1 (en) | 1996-03-21 |
CN1096850C (zh) | 2002-12-25 |
CN1166136A (zh) | 1997-11-26 |
NO971149L (no) | 1997-05-13 |
EP0781123A1 (en) | 1997-07-02 |
EP0781123A4 (en) | 2000-12-20 |
NZ334561A (en) | 2000-01-28 |
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