MX9600016A - Cristalizacion del ester metilico de a-l-aspartil-l-fenilalanina a partir de una solucion acuosa. - Google Patents
Cristalizacion del ester metilico de a-l-aspartil-l-fenilalanina a partir de una solucion acuosa.Info
- Publication number
- MX9600016A MX9600016A MX9600016A MX9600016A MX9600016A MX 9600016 A MX9600016 A MX 9600016A MX 9600016 A MX9600016 A MX 9600016A MX 9600016 A MX9600016 A MX 9600016A MX 9600016 A MX9600016 A MX 9600016A
- Authority
- MX
- Mexico
- Prior art keywords
- drops
- aspartame
- aqueous solution
- aspartyl
- water
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Seasonings (AREA)
Abstract
El invento se refiere a un método para enfriar una solucion acuosa de aspartamo y cristalizar el aspartamo desde ésta con evitacion de turbulencia en el sistema acuoso de cristalizacion, (i) alimentando una solucion acuosa caliente de aspartamo a unos metros para dispersar gotitas; (ii) dispersando éstas en un líquido inmiscible con agua a una temperatura menor de al menos 20 degree C, de manera tal que no se producirá nucleacion en las gotitas mientras que éstas estén pasando por dicho líquido inmiscible con agua; (iii) enfriar dicho líquido inmiscible con agua de manera tal que dichas gotitas sean enfriadas eficazmente para alcanzar una sobresaturacion relativa inicial de éster metílico de a-L-aspartil-L-fenilalanina dentro de las gotitas en el margen de 1 a 6, preferiblemente de 1,2 a 4; (iv) recoger las gotitas enfriadas para dar aspartamo cristalino; (v) y proporcionar tiempo suficiente para ello.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94203726 | 1994-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9600016A true MX9600016A (es) | 1997-06-28 |
Family
ID=8217481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9600016A MX9600016A (es) | 1994-12-22 | 1996-01-03 | Cristalizacion del ester metilico de a-l-aspartil-l-fenilalanina a partir de una solucion acuosa. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5637754A (es) |
| KR (1) | KR960022557A (es) |
| CN (1) | CN1130192A (es) |
| AT (1) | ATE201694T1 (es) |
| DE (1) | DE69521110T2 (es) |
| MX (1) | MX9600016A (es) |
| RU (1) | RU2155635C2 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20000009984A (ko) * | 1998-07-29 | 2000-02-15 | 고두모 | 알파-엘-아스파틸-엘-페닐알라닌 메틸 에스테르의 결정화 방법 |
| US6643950B2 (en) * | 2000-12-06 | 2003-11-11 | Eisai Co., Ltd. | System and method for measuring freeze dried cake resistance |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| WO2014020854A1 (ja) * | 2012-08-03 | 2014-02-06 | Ｊｆｅスチール株式会社 | 晶析装置及び晶析方法 |
| CN105641967B (zh) * | 2016-04-01 | 2017-09-26 | 武汉科技大学 | 一种赤藓糖醇的连续结晶方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0832719B2 (ja) * | 1986-12-19 | 1996-03-29 | 三井東圧化学株式会社 | 吸湿性の小さいα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法 |
-
1995
- 1995-12-18 DE DE69521110T patent/DE69521110T2/de not_active Expired - Fee Related
- 1995-12-18 AT AT95203533T patent/ATE201694T1/de active
- 1995-12-20 US US08/575,713 patent/US5637754A/en not_active Expired - Fee Related
- 1995-12-21 RU RU95122456/04A patent/RU2155635C2/ru active
- 1995-12-21 CN CN95121754A patent/CN1130192A/zh active Pending
- 1995-12-22 KR KR1019950054015A patent/KR960022557A/ko not_active Application Discontinuation
-
1996
- 1996-01-03 MX MX9600016A patent/MX9600016A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2155635C2 (ru) | 2000-09-10 |
| DE69521110T2 (de) | 2002-03-07 |
| KR960022557A (ko) | 1996-07-18 |
| CN1130192A (zh) | 1996-09-04 |
| DE69521110D1 (de) | 2001-07-05 |
| ATE201694T1 (de) | 2001-06-15 |
| US5637754A (en) | 1997-06-10 |
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