ATE201694T1 - Crystallisierung vom alpha-l-aspartyl-l- phenylalanylmethylester aus wässrigen lösungen - Google Patents

Crystallisierung vom alpha-l-aspartyl-l- phenylalanylmethylester aus wässrigen lösungen

Info

Publication number
ATE201694T1
ATE201694T1 AT95203533T AT95203533T ATE201694T1 AT E201694 T1 ATE201694 T1 AT E201694T1 AT 95203533 T AT95203533 T AT 95203533T AT 95203533 T AT95203533 T AT 95203533T AT E201694 T1 ATE201694 T1 AT E201694T1
Authority
AT
Austria
Prior art keywords
aspartame
dispersed droplets
water
droplets
aspartyl
Prior art date
Application number
AT95203533T
Other languages
English (en)
Inventor
Marinus P W M Rijkers
Antoon G T Toussaint
Alexander P M Vrinzen
Original Assignee
Holland Sweetener Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Holland Sweetener Co filed Critical Holland Sweetener Co
Application granted granted Critical
Publication of ATE201694T1 publication Critical patent/ATE201694T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
AT95203533T 1994-12-22 1995-12-18 Crystallisierung vom alpha-l-aspartyl-l- phenylalanylmethylester aus wässrigen lösungen ATE201694T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94203726 1994-12-22

Publications (1)

Publication Number Publication Date
ATE201694T1 true ATE201694T1 (de) 2001-06-15

Family

ID=8217481

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95203533T ATE201694T1 (de) 1994-12-22 1995-12-18 Crystallisierung vom alpha-l-aspartyl-l- phenylalanylmethylester aus wässrigen lösungen

Country Status (7)

Country Link
US (1) US5637754A (de)
KR (1) KR960022557A (de)
CN (1) CN1130192A (de)
AT (1) ATE201694T1 (de)
DE (1) DE69521110T2 (de)
MX (1) MX9600016A (de)
RU (1) RU2155635C2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000009984A (ko) * 1998-07-29 2000-02-15 고두모 알파-엘-아스파틸-엘-페닐알라닌 메틸 에스테르의 결정화 방법
JP4179881B2 (ja) * 2000-12-06 2008-11-12 エーザイ株式会社 凍結乾燥ケークの抵抗を測定するためのシステム及び方法
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
WO2014020854A1 (ja) * 2012-08-03 2014-02-06 Ｊｆｅスチール株式会社 晶析装置及び晶析方法
CN105641967B (zh) * 2016-04-01 2017-09-26 武汉科技大学 一种赤藓糖醇的连续结晶方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173562A (en) * 1976-12-27 1979-11-06 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester
EP0101755A1 (de) * 1982-08-31 1984-03-07 Chimicasa Gmbh Wassarlösliche, durch Pressen verfestigte Süssungstablette
IT1214875B (it) * 1984-06-21 1990-01-18 Ferrero Spa Prodotto confettato e procedimento per la sua fabbricazione
JPH0832719B2 (ja) * 1986-12-19 1996-03-29 三井東圧化学株式会社 吸湿性の小さいα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法
DE68925450T2 (de) * 1988-10-03 1996-09-19 Ajinomoto Kk Verfahren zur Herstellung von trockenen IB Kristallen des alpha-L-Aspartyl-L-phenylalaninmethylesters, die eine verbesserte Löslichkeit besitzen
FR2650158B1 (fr) * 1989-07-31 1992-10-30 Searle France Nouvelle composition notamment utile pour la preparation d'un produit sucrant destine a la consommation alimentaire; procedes de preparation de cette composition et dudit produit sucrant qu'elle permet d'obtenir
JP2970107B2 (ja) * 1991-05-23 1999-11-02 味の素株式会社 α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの製造方法
BR9205373A (pt) * 1991-07-19 1994-03-08 Tosoh Corp Processo para cristalizacao de ester alfa-i-aspartil-i-fenilalanina metilico
RU2092490C1 (ru) * 1991-07-19 1997-10-10 Тосох корпорейшн Способ кристаллизации метилового эфира альфа-l-аспартил-l-фенилаланина
ATE145920T1 (de) * 1991-07-19 1996-12-15 Holland Sweetener Co Verfahren zur kristallisation von alpha-l- aspartyl-l-phenylalaninmethylester
ATE145650T1 (de) * 1991-07-19 1996-12-15 Holland Sweetener Co Verfahren zur kristallisation von alpha-l- aspartyl-l-phenylalaninmethylester
JP3094684B2 (ja) * 1992-09-04 2000-10-03 味の素株式会社 ジペプチド甘味料顆粒の製造法
US5474791A (en) * 1993-10-20 1995-12-12 The Nutrasweet Company Beverages using tamarind extract and method of making such beverages
RU2083585C1 (ru) * 1994-12-13 1997-07-10 Волгоградское акционерное общество открытого типа "Химпром" Способ получения метилового эфира n-бензилоксикарбонил-l-аспартил-l-фенилаланина

Also Published As

Publication number Publication date
DE69521110T2 (de) 2002-03-07
RU2155635C2 (ru) 2000-09-10
KR960022557A (ko) 1996-07-18
MX9600016A (es) 1997-06-28
US5637754A (en) 1997-06-10
DE69521110D1 (de) 2001-07-05
CN1130192A (zh) 1996-09-04

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