MX9401387A - Inmovilizacion de reactivos para un ensayo de un enlace especifico. - Google Patents

Inmovilizacion de reactivos para un ensayo de un enlace especifico.

Info

Publication number
MX9401387A
MX9401387A MX9401387A MX9401387A MX9401387A MX 9401387 A MX9401387 A MX 9401387A MX 9401387 A MX9401387 A MX 9401387A MX 9401387 A MX9401387 A MX 9401387A MX 9401387 A MX9401387 A MX 9401387A
Authority
MX
Mexico
Prior art keywords
specific binding
reagents
immobilization
test
solid phase
Prior art date
Application number
MX9401387A
Other languages
English (en)
Inventor
Steven E Diamond
Spencer H Lin
Pratap Singh
Kwok Sum Yu
Original Assignee
Baxter Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Diagnostics Inc filed Critical Baxter Diagnostics Inc
Publication of MX9401387A publication Critical patent/MX9401387A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/811—Peptides or proteins is immobilized on, or in, an inorganic carrier

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se proporcionan métodos y composiciones para ensayos de enlace específico, en los cuales los reactivos de enlace específico están inmovilizados sobre una fase sólida. La inmovilización es facilitada por los reactivos de ensayo de enlace específico de unión covalente, tales como receptores de polipéptidos o analíticos con polímeros solubles en agua. Tales polímeros solubles en agua, por ejemplo, polímeros de estrella, tales como dendrímeros, proporcionan ventajas de producción de uniformidad de lote a lote y homogeneidad y pueden aumentar la sensibilidad debido al poco enlace no específico a la fase sólida.
MX9401387A 1993-02-24 1994-02-23 Inmovilizacion de reactivos para un ensayo de un enlace especifico. MX9401387A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2192893A 1993-02-24 1993-02-24

Publications (1)

Publication Number Publication Date
MX9401387A true MX9401387A (es) 1994-08-31

Family

ID=21806909

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9401387A MX9401387A (es) 1993-02-24 1994-02-23 Inmovilizacion de reactivos para un ensayo de un enlace especifico.

Country Status (11)

Country Link
US (1) US5861319A (es)
EP (1) EP0637385B1 (es)
JP (1) JP3366978B2 (es)
AT (1) ATE178717T1 (es)
AU (1) AU6267794A (es)
CA (1) CA2133967A1 (es)
DE (1) DE69417645T2 (es)
ES (1) ES2132392T3 (es)
MX (1) MX9401387A (es)
WO (1) WO1994019693A1 (es)
ZA (1) ZA941084B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5898005A (en) * 1993-02-24 1999-04-27 Dade Behring Inc. Rapid detection of analytes with receptors immobilized on soluble submicron particles
US6121056A (en) * 1993-02-24 2000-09-19 Dade Behring Inc. Random detection of antigens with antibodies immobilized on soluble submicron particles
US6083708A (en) * 1995-08-11 2000-07-04 Dade Behring Inc. Polypeptide: dendrimer complexes
US6117631A (en) * 1996-10-29 2000-09-12 Polyprobe, Inc. Detection of antigens via oligonucleotide antibody conjugates
US6133436A (en) 1996-11-06 2000-10-17 Sequenom, Inc. Beads bound to a solid support and to nucleic acids
EP1086375A4 (en) * 1998-06-12 2004-12-15 New Horizons Diagnostics Inc COLLOIDAL COLORIMETRIC TESTS IN CONTINUOUS FLOW AND SIDE FLOW USING SOLUBLE SUBMICRONIC PARTICLES
US6404500B1 (en) * 1999-01-25 2002-06-11 Aqua Check Systems, Inc Colorimeter apparatus and related process
US6471968B1 (en) 2000-05-12 2002-10-29 Regents Of The University Of Michigan Multifunctional nanodevice platform
KR100377946B1 (ko) * 2000-07-15 2003-03-29 한국과학기술원 덴드리머를 이용한 단분자막의 제조방법
US7501157B2 (en) * 2001-06-26 2009-03-10 Accelr8 Technology Corporation Hydroxyl functional surface coating
US6844028B2 (en) * 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US20030108972A1 (en) * 2001-12-06 2003-06-12 Zweig Stephen Eliot Tethered receptor-ligand reagent and assay
US9671396B2 (en) * 2001-09-05 2017-06-06 Joon Won Park Solid substrate comprising array of dendrons and methods for using the same
DE10332849A1 (de) * 2003-07-18 2005-02-17 Sustech Gmbh & Co. Kg Arrays immobilisierter Biomoleküle auf Hydrogel-bildenden Oberflächen, deren Herstellung und deren Verwendung
CA2545653C (en) * 2003-11-21 2014-07-08 Anp Technologies, Inc. Asymmetrically branched polymer conjugates and microarray assays
CA2578205A1 (en) * 2004-08-25 2006-03-30 The Regents Of The University Of Michigan Partially acetylated dendrimers and related methods of use
WO2006102484A2 (en) * 2005-03-21 2006-09-28 Anp Technologies, Inc. Symmetrically branched polymer conjugates and microarray assays
ATE496297T1 (de) 2005-05-02 2011-02-15 Anp Technologies Inc Polymerkonjugat-verbesserte bioassays
US20070015166A1 (en) * 2005-07-14 2007-01-18 Nilsen Thor W Lateral flow methods and devices for detection of nucleic acid binding proteins
US20070041934A1 (en) * 2005-08-12 2007-02-22 Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US8492098B2 (en) 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
JP2009527471A (ja) * 2006-02-21 2009-07-30 ミプサルス エーピーエス 分子インプリントポリマの改良した調製方法
WO2009009203A2 (en) * 2007-04-19 2009-01-15 The Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US8252834B2 (en) 2008-03-12 2012-08-28 The Regents Of The University Of Michigan Dendrimer conjugates
DE102008018180A1 (de) * 2008-04-02 2009-10-15 Hansgrohe Ag Verfahren zum Nachweis von perfluorierten Tensiden
WO2010039861A2 (en) 2008-09-30 2010-04-08 The Regents Of The University Of Michigan Dendrimer conjugates
US9017644B2 (en) 2008-11-07 2015-04-28 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
CN102917699A (zh) 2009-10-13 2013-02-06 密执安大学评议会 树枝状聚合物组合物和合成方法
US8912323B2 (en) 2009-10-30 2014-12-16 The Regents Of The University Of Michigan Multifunctional small molecules
US8114197B2 (en) * 2009-12-22 2012-02-14 Hollingsworth & Vose Company Filter media and articles including dendrimers and/or other components
US10669522B2 (en) 2011-02-07 2020-06-02 Life Technologies Corporation Compositions and methods for stabilizing susceptible compounds
US9402911B2 (en) 2011-12-08 2016-08-02 The Regents Of The University Of Michigan Multifunctional small molecules
KR20200109293A (ko) 2017-09-13 2020-09-22 프로제너티, 인크. 자간전증 바이오마커 및 관련된 시스템 및 방법
EP4070113A4 (en) 2019-12-04 2023-12-20 Biora Therapeutics, Inc. ASSESSMENT OF PREECAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR ASSAYS

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363634A (en) * 1980-07-18 1982-12-14 Akzona Incorporated Glass support coated with synthetic polymer for bioprocess
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US4507466A (en) * 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4568737A (en) * 1983-01-07 1986-02-04 The Dow Chemical Company Dense star polymers and dendrimers
US5482830A (en) * 1986-02-25 1996-01-09 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5468606A (en) * 1989-09-18 1995-11-21 Biostar, Inc. Devices for detection of an analyte based upon light interference
US4694064A (en) * 1986-02-28 1987-09-15 The Dow Chemical Company Rod-shaped dendrimer
US5338532A (en) * 1986-08-18 1994-08-16 The Dow Chemical Company Starburst conjugates
ES2054678T5 (es) * 1986-08-18 1997-09-16 Dow Chemical Co Conjugados estrella.
US5364613A (en) * 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
US5914095A (en) * 1989-04-07 1999-06-22 Salutar, Inc. Polychelants containg amide bonds
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
US5171264A (en) * 1990-02-28 1992-12-15 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
US5418136A (en) * 1991-10-01 1995-05-23 Biostar, Inc. Devices for detection of an analyte based upon light interference
EP0727038B1 (en) * 1992-07-31 2005-12-14 Thermo Biostar, Inc. Devices and methods for detection of an analyte based upon light interference

Also Published As

Publication number Publication date
WO1994019693A1 (en) 1994-09-01
DE69417645D1 (de) 1999-05-12
AU6267794A (en) 1994-09-14
CA2133967A1 (en) 1994-09-01
JP3366978B2 (ja) 2003-01-14
ES2132392T3 (es) 1999-08-16
ZA941084B (en) 1995-08-17
US5861319A (en) 1999-01-19
DE69417645T2 (de) 1999-12-16
EP0637385B1 (en) 1999-04-07
JPH07506195A (ja) 1995-07-06
EP0637385A1 (en) 1995-02-08
ATE178717T1 (de) 1999-04-15

Similar Documents

Publication Publication Date Title
MX9401387A (es) Inmovilizacion de reactivos para un ensayo de un enlace especifico.
DE69521253D1 (de) Schnellnachweis von analyten mit auf löslichen submikron-teilchen immobilisierten rezeptoren
DE59108149D1 (de) Universalbindefilm
DE3485920D1 (de) Kolorimetrisches immunoessay auf fester oberflaeche, sowie dazu zu verwendender teststab und seine herstellung.
ATE88762T1 (de) Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden.
EP0146654A3 (en) Processes and apparatus for carrying out specific binding assays
SE9604575D0 (sv) Method and system for analyte determination
FI90799C (fi) Immunologisia määritysmenetelmiä ja niissä käytettävä reagenssi
AU582293B2 (en) Heterogeneous specific binding assay employing an aggregatable binding reagent
US5164311A (en) Preparation of an antibody-enzyme conjugate
KR900002075A (ko) 특이적으로 결합가능한 물질의 정량 방법 및 시약
JPH0734859B2 (ja) 免疫検定およびバイオアフイニテイ分離のための蛋白質固定化への疎水性基で誘導体化されたポリ（エチレンイミン）の応用
DK516387D0 (da) Fremgangsmaade til immunometrisk bestemmelse
ES2087940T3 (es) Procedimiento inmunologico de precipitacion para la determinacion de un analito fijable y reactivo para la ejecucion de dicho procedimiento.
Charles et al. Characterization and performance evaluation of in vivo and in vitro produced monoclonal anti-TNT antibodies for the detection of TNT
ATE170927T1 (de) Ionenfang-analysenverfahren, die einen an carboxymethylamylose konjugierten bindungspartner verwenden
DE58907087D1 (de) Verfahren zur Bestimmung von für ein Antigen klassenspezifischen Antikörpern und dazu geeignetes Reagenz.
Schmidt Jr et al. An advanced solid support for immunoassays and other affinity applications
ATE182172T1 (de) Immunologischer nachweis von metolachlor
ES479985A1 (es) Un metodo mejorado para la deteccion y determinacion de un -acido biliar.
ATE200353T1 (de) Kompetitiver immuntest unter verwendung komplexierter analytderivate
ES2055031T3 (es) Ensayo de enzima de preincubacion de receptor.
ATE24055T1 (de) Heterogenes testverfahren fuer antigenische biologische substanzen mittels antikoerperhybridkonjugaten und reagens dafuer.
KR970007351A (ko) 활성화된 인자의 정량방법
ATE302949T1 (de) Knorpelresorptionsassays