DE69521253D1 - Schnellnachweis von analyten mit auf löslichen submikron-teilchen immobilisierten rezeptoren - Google Patents

Schnellnachweis von analyten mit auf löslichen submikron-teilchen immobilisierten rezeptoren

Info

Publication number
DE69521253D1
DE69521253D1 DE69521253T DE69521253T DE69521253D1 DE 69521253 D1 DE69521253 D1 DE 69521253D1 DE 69521253 T DE69521253 T DE 69521253T DE 69521253 T DE69521253 T DE 69521253T DE 69521253 D1 DE69521253 D1 DE 69521253D1
Authority
DE
Germany
Prior art keywords
analytes
sample
specific binding
quick detection
submicron particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69521253T
Other languages
English (en)
Other versions
DE69521253T2 (de
Inventor
Moll, Iii
Charles Ferzli
Spencer Lin
Pratap Singh
Richard Saul
Kent Koshi
Peter Cronin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dade International Inc
Original Assignee
Dade International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade International Inc filed Critical Dade International Inc
Publication of DE69521253D1 publication Critical patent/DE69521253D1/de
Application granted granted Critical
Publication of DE69521253T2 publication Critical patent/DE69521253T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
DE69521253T 1994-04-13 1995-04-11 Schnellnachweis von analyten mit auf löslichen submikron-teilchen immobilisierten rezeptoren Expired - Fee Related DE69521253T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/227,364 US5898005A (en) 1993-02-24 1994-04-13 Rapid detection of analytes with receptors immobilized on soluble submicron particles
PCT/US1995/004313 WO1995028641A1 (en) 1994-04-13 1995-04-11 Rapid detection of analytes with receptors immobilized on soluble submicron particles

Publications (2)

Publication Number Publication Date
DE69521253D1 true DE69521253D1 (de) 2001-07-19
DE69521253T2 DE69521253T2 (de) 2002-05-02

Family

ID=22852804

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69521253T Expired - Fee Related DE69521253T2 (de) 1994-04-13 1995-04-11 Schnellnachweis von analyten mit auf löslichen submikron-teilchen immobilisierten rezeptoren

Country Status (8)

Country Link
US (1) US5898005A (de)
EP (1) EP0704058B1 (de)
JP (1) JP3530957B2 (de)
AT (1) ATE202213T1 (de)
AU (1) AU2243195A (de)
CA (1) CA2164939A1 (de)
DE (1) DE69521253T2 (de)
WO (1) WO1995028641A1 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083708A (en) * 1995-08-11 2000-07-04 Dade Behring Inc. Polypeptide: dendrimer complexes
AU3880097A (en) 1996-08-14 1998-03-06 Warner-Lambert Company Low molecular weight dendritic compounds as pharmaceutical agents
AU9673198A (en) * 1997-10-02 1999-04-27 Aclara Biosciences, Inc. Capillary assays involving separation of free and bound species
US6322980B1 (en) * 1999-04-30 2001-11-27 Aclara Biosciences, Inc. Single nucleotide detection using degradation of a fluorescent sequence
US7160735B2 (en) * 2000-04-28 2007-01-09 Monogram Biosciences, Inc. Tagged microparticle compositions and methods
US7771929B2 (en) * 2000-04-28 2010-08-10 Monogram Biosciences, Inc. Tag library compounds, compositions, kits and methods of use
US6471968B1 (en) 2000-05-12 2002-10-29 Regents Of The University Of Michigan Multifunctional nanodevice platform
KR100377946B1 (ko) * 2000-07-15 2003-03-29 한국과학기술원 덴드리머를 이용한 단분자막의 제조방법
JP2004510161A (ja) * 2000-09-25 2004-04-02 アボット・ラボラトリーズ 高分子ポリカチオンを用いることにより、特異的結合アッセイにおける血清または血漿含有アッセイ試料の干渉を減少させるための方法及びキット
WO2002054052A1 (en) * 2001-01-08 2002-07-11 Leonard Fish Diagnostic instruments and methods for detecting analytes
DE60144014D1 (de) * 2001-07-19 2011-03-24 Max Planck Gesellschaft Chemische Sensoren aus Nanopartikel-Dendrimer-Komposit-Materialen
KR20040108655A (ko) * 2002-03-05 2004-12-24 아클라라 바이오사이언시스 인코퍼레이티드 막-결합된 민감제를 사용하는 복합 분석법
US7105308B2 (en) 2002-07-25 2006-09-12 Monogram Biosciences, Inc. Detecting receptor oligomerization
US20040229380A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB heterodimers as biomarkers
WO2004010842A2 (en) * 2002-07-26 2004-02-05 Aclara Biosciences, Inc. Lipophilic electrophoretic probes
US20120077206A1 (en) 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
US7341841B2 (en) 2003-07-12 2008-03-11 Accelr8 Technology Corporation Rapid microbial detection and antimicrobial susceptibility testing
CA2532414C (en) 2003-07-12 2017-03-14 Accelr8 Technology Corporation Sensitive and rapid biodetection
US7402398B2 (en) * 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
US20050130246A1 (en) * 2003-10-27 2005-06-16 Hossein Salimi-Moosavi Detecting human anti-therapeutic antibodies
WO2005051295A2 (en) * 2003-11-21 2005-06-09 Anp Technologies, Inc. Asymmetrically branched polymer conjugates and microarray assays
US20050249921A1 (en) * 2004-05-04 2005-11-10 Ward William W Forming artistic works from medusae
JP2008510829A (ja) * 2004-08-25 2008-04-10 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン デンドリマーに基づく組成物およびそれらの使用法
WO2006102484A2 (en) * 2005-03-21 2006-09-28 Anp Technologies, Inc. Symmetrically branched polymer conjugates and microarray assays
WO2006119160A2 (en) 2005-05-02 2006-11-09 Anp Technologies, Inc. Polymer conjugate enhanced bioassays
US20070041934A1 (en) * 2005-08-12 2007-02-22 Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US8460879B2 (en) 2006-02-21 2013-06-11 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
CA2684725A1 (en) * 2007-04-19 2009-01-15 The Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US8252834B2 (en) 2008-03-12 2012-08-28 The Regents Of The University Of Michigan Dendrimer conjugates
DE102008018180A1 (de) * 2008-04-02 2009-10-15 Hansgrohe Ag Verfahren zum Nachweis von perfluorierten Tensiden
US8889635B2 (en) 2008-09-30 2014-11-18 The Regents Of The University Of Michigan Dendrimer conjugates
US9017644B2 (en) 2008-11-07 2015-04-28 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
US8945508B2 (en) 2009-10-13 2015-02-03 The Regents Of The University Of Michigan Dendrimer compositions and methods of synthesis
US8912323B2 (en) 2009-10-30 2014-12-16 The Regents Of The University Of Michigan Multifunctional small molecules
JP6143679B2 (ja) 2011-02-07 2017-06-07 ライフ テクノロジーズ コーポレーション 感受性化合物を安定化するための組成物および方法
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
EP2683831B1 (de) 2011-03-07 2015-09-23 Accelerate Diagnostics, Inc. Schnelle zellreinigungssysteme
US9140633B2 (en) 2011-06-03 2015-09-22 Ut-Battelle, Llc Enhanced spot preparation for liquid extractive sampling and analysis
WO2013085718A1 (en) 2011-12-08 2013-06-13 The Regents Of The University Of Michigan Multifunctional small molecules
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
CN107430119A (zh) * 2015-03-10 2017-12-01 西门子医疗保健诊断公司 固体载体上的官能团的定量
US10048256B2 (en) * 2015-03-18 2018-08-14 Bio-Rad Laboratories, Inc. Sample analysis systems and methods
EP3278115A2 (de) 2015-03-30 2018-02-07 Accelerate Diagnostics, Inc. Instrument und system zum schnellen identifizieren von mikroorganismen und testen der antimikrobiellen wirkstoffempfindlichkeit
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
JP2020533595A (ja) 2017-09-13 2020-11-19 プロジェニティ， インコーポレイテッド 子癇前症バイオマーカならびに関連するシステムおよび方法
EP4070113A4 (de) 2019-12-04 2023-12-20 Biora Therapeutics, Inc. Beurteilung von präeklampsie unter verwendung von tests für freien und dissoziierten plazentalen wachstumsfaktor

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363634A (en) * 1980-07-18 1982-12-14 Akzona Incorporated Glass support coated with synthetic polymer for bioprocess
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4507466A (en) * 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4568737A (en) * 1983-01-07 1986-02-04 The Dow Chemical Company Dense star polymers and dendrimers
US5482830A (en) * 1986-02-25 1996-01-09 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5468606A (en) * 1989-09-18 1995-11-21 Biostar, Inc. Devices for detection of an analyte based upon light interference
US4694064A (en) * 1986-02-28 1987-09-15 The Dow Chemical Company Rod-shaped dendrimer
ATE89743T1 (de) * 1986-08-18 1993-06-15 Dow Chemical Co Conjugate dichter sterne.
US5914095A (en) * 1989-04-07 1999-06-22 Salutar, Inc. Polychelants containg amide bonds
US5364613A (en) * 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
US5171264A (en) * 1990-02-28 1992-12-15 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
EP0727038B1 (de) * 1992-07-31 2005-12-14 Thermo Biostar, Inc. Vorrichtungen und Verfahren zur Detektion eines Analyten mittels optischer Interferenz
EP0637385B1 (de) * 1993-02-24 1999-04-07 Dade Behring Inc. Immobilisierung von reagenzien für spezifische bindungsassay

Also Published As

Publication number Publication date
ATE202213T1 (de) 2001-06-15
JP3530957B2 (ja) 2004-05-24
EP0704058B1 (de) 2001-06-13
JPH09501503A (ja) 1997-02-10
CA2164939A1 (en) 1995-10-26
EP0704058A1 (de) 1996-04-03
US5898005A (en) 1999-04-27
WO1995028641A1 (en) 1995-10-26
AU2243195A (en) 1995-11-10
DE69521253T2 (de) 2002-05-02

Similar Documents

Publication Publication Date Title
DE69521253D1 (de) Schnellnachweis von analyten mit auf löslichen submikron-teilchen immobilisierten rezeptoren
DE69417645D1 (de) Immobilisierung von reagenzien für spezifische bindungsassay
Bao Capillary electrophoretic immunoassays
EP0138826B1 (de) Nachweis menschlichen chorionischen gonadotropins
US5223393A (en) Detection of analytes having binding sites for at least two binding moieties
DE3485920D1 (de) Kolorimetrisches immunoessay auf fester oberflaeche, sowie dazu zu verwendender teststab und seine herstellung.
ATE221997T1 (de) Immunoassays zum nachweis von antiphospholipid- antikörpern
AU3156489A (en) Solid-phase analytical device and method for using same
KR910008407A (ko) 개선된 자동 면역크로마토그래프 장치
ATE63167T1 (de) Heterogener spezifischer bindungstest unter verwendung eines anhaeufbaren bindungsreagens.
FI90799C (fi) Immunologisia määritysmenetelmiä ja niissä käytettävä reagenssi
KR960029789A (ko) 생체내 물질의 면역학적 분석용 키트 및 면역학적 분석 방법
CN205193076U (zh) 一种生物素-亲和素系统快速检测卡
CA2286414A1 (en) Non-separation heterogenous assay for biological substance
DE59712595D1 (de) Homogene Nachweisverfahren zur Bestimmung von Subpopulationen eines Analyten
AU2004205779B2 (en) Surface layer affinity-chromatography
DE58907087D1 (de) Verfahren zur Bestimmung von für ein Antigen klassenspezifischen Antikörpern und dazu geeignetes Reagenz.
MY106963A (en) Agglutination assay.
ES479985A1 (es) Un metodo mejorado para la deteccion y determinacion de un -acido biliar.
KR890006828A (ko) 효소 분석법
ATE413601T1 (de) Methode zur zellulären high-throughput-detektion von rezeptor-liganden-interaktionen
RU2314827C2 (ru) Способ получения конъюгата для стереоспецифического анализа
ES2055031T3 (es) Ensayo de enzima de preincubacion de receptor.
JPH0694713A (ja) アンチトロンビンｉｉｉ活性の測定方法とそれを用いたアンチトロンビンｉｉｉ活性の測定キット
Maggio et al. Immunology: current and future technology assessment

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee