ES2087940T3 - Procedimiento inmunologico de precipitacion para la determinacion de un analito fijable y reactivo para la ejecucion de dicho procedimiento. - Google Patents
Procedimiento inmunologico de precipitacion para la determinacion de un analito fijable y reactivo para la ejecucion de dicho procedimiento.Info
- Publication number
- ES2087940T3 ES2087940T3 ES91116392T ES91116392T ES2087940T3 ES 2087940 T3 ES2087940 T3 ES 2087940T3 ES 91116392 T ES91116392 T ES 91116392T ES 91116392 T ES91116392 T ES 91116392T ES 2087940 T3 ES2087940 T3 ES 2087940T3
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- determination
- fixable
- execution
- analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000001900 immune effect Effects 0.000 title abstract 2
- 238000001556 precipitation Methods 0.000 title abstract 2
- 239000012491 analyte Substances 0.000 title 1
- 239000012085 test solution Substances 0.000 abstract 2
- 229920002307 Dextran Polymers 0.000 abstract 1
- -1 POLYETHYLENE Polymers 0.000 abstract 1
- 239000004698 Polyethylene Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 229920000573 polyethylene Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
- G01N15/075—Investigating concentration of particle suspensions by optical means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
LA INVENCION TRATA DE UN METODO DE PRECIPITACION INMUNOLOGICA PARA LA DETERMINACION DE UN ANALISIS CON LIGANTE MEDIANTE LA INCUBACION DE UNA SOLUCION DE PRUEBA QUE CONTIENE EL ANALISIS CON UN RECEPTOR ESPECIFICO Y LIGANTE CON CAPACIDAD DE ANALISIS. ESTA INVENCION SE CARACTERIZA PORQUE LA SOLUCION DE PRUEBA ES UN POLIMERO NO IONIZADO QUE SE BASA EN EL GRUPO AL QUE SE AÑADE: DEXTRAN, CON UN PESO MOLECULAR DE MAS DE 500.000, POLIVINILPIRROLIDON CON UN PESO MOLECULAR DE MAS DE 100.000 Y POLIETILENGLICOL CON UN PESO MOLECULAR DE MAS DE 10.000, ASI COMO UNA REACCION APROPIADA PARA EL MISMO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4034509A DE4034509A1 (de) | 1990-10-30 | 1990-10-30 | Immunologisches praezipitationsverfahren zur bestimmung eines bindefaehigen analyten sowie reagenz zur durchfuehrung dieses verfahrens |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2087940T3 true ES2087940T3 (es) | 1996-08-01 |
Family
ID=6417324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91116392T Expired - Lifetime ES2087940T3 (es) | 1990-10-30 | 1991-09-26 | Procedimiento inmunologico de precipitacion para la determinacion de un analito fijable y reactivo para la ejecucion de dicho procedimiento. |
Country Status (8)
Country | Link |
---|---|
US (1) | US6210975B1 (es) |
EP (1) | EP0483512B1 (es) |
JP (1) | JPH04248465A (es) |
AT (1) | ATE130683T1 (es) |
AU (1) | AU8472891A (es) |
CA (1) | CA2052165A1 (es) |
DE (2) | DE4034509A1 (es) |
ES (1) | ES2087940T3 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4140142A1 (de) * | 1991-12-05 | 1993-06-09 | Boehringer Mannheim Gmbh, 6800 Mannheim, De | Multivalentes dextranreagenz zum einsatz in praezipitationstests |
DE4309393A1 (de) * | 1993-03-23 | 1994-09-29 | Boehringer Mannheim Gmbh | Verringerung des Hook-Effekts in Immuntests mit teilchenförmigem Trägermaterial |
DE19602491A1 (de) * | 1996-01-25 | 1997-07-31 | Bayer Ag | Verfahren zur Vergrößerung des Assay-Bereiches und zum Vermeiden des Hook-Effektes bei simultanen Sandwich-Immunoassays und entsprechende Testkits |
JP3298812B2 (ja) | 1997-08-15 | 2002-07-08 | アークレイ株式会社 | 尿中トリプシンインヒビターの測定方法 |
ATE221657T1 (de) | 1998-05-06 | 2002-08-15 | Roche Diagnostics Gmbh | Entstörung durch rheumafaktoren |
JP4219491B2 (ja) * | 1999-06-18 | 2009-02-04 | 富士フイルム株式会社 | 乾式分析方法及び乾式分析要素 |
JP2003294753A (ja) * | 2002-04-01 | 2003-10-15 | Kyokuto Seiyaku Kogyo Kk | 凝集反応増感剤、免疫測定用試薬及び免疫測定法 |
EP1496362B1 (en) * | 2003-07-09 | 2006-12-13 | Matsushita Electric Industrial Co., Ltd. | Turbidimetric immunoassay and an apparatus therefor |
DE102006000707A1 (de) * | 2006-01-03 | 2007-07-05 | Qiagen Gmbh | Verwendung von Polymeren zur Erhöhung der Signalintensität bei der Durchführung von Nachweisreaktionen |
CN109406498B (zh) * | 2017-08-15 | 2024-03-29 | 科美博阳诊断技术(上海)有限公司 | 一种免疫测定装置 |
BE1025353B1 (nl) * | 2017-12-22 | 2019-01-29 | Aptec Diagnostics Nv | Vloeibaar reagens voor immunochemische bepalingen |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL213501A (es) | 1972-03-10 | |||
US4298592A (en) * | 1979-04-05 | 1981-11-03 | Mallinckrodt, Inc. | Double antibody separation method |
FI792576A (fi) * | 1979-08-20 | 1981-02-21 | Orion Yhtymae Oy | Foerbaettrad metod att utfoera enzymimmunologiska bestaemningar |
JPS582660A (ja) | 1981-06-30 | 1983-01-08 | Chugai Pharmaceut Co Ltd | 免疫学的試薬 |
US4595661A (en) * | 1983-11-18 | 1986-06-17 | Beckman Instruments, Inc. | Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect |
DE3347162A1 (de) * | 1983-12-27 | 1985-07-04 | Behringwerke Ag, 3550 Marburg | Photometrisches verfahren zur konzentrationsbestimmung bei reaktionen, die unter bildung oder verbrauch von streuzentren verlaufen |
JPH02500133A (ja) * | 1987-07-21 | 1990-01-18 | クールター・エレクトロニクス・インコーポレーテッド | ハプテンについての改良濁り測定抑制検定法 |
JPH01104198A (ja) | 1987-10-16 | 1989-04-21 | Amano Pharmaceut Co Ltd | 分析の精度を向上させる方法 |
US5102788A (en) * | 1988-11-21 | 1992-04-07 | Hygeia Sciences, Inc. | Immunoassay including lyophilized reactant mixture |
JP2682697B2 (ja) | 1989-03-29 | 1997-11-26 | 積水化学工業株式会社 | 免疫測定試薬および免疫測定法 |
-
1990
- 1990-10-30 DE DE4034509A patent/DE4034509A1/de not_active Withdrawn
-
1991
- 1991-09-24 AU AU84728/91A patent/AU8472891A/en not_active Abandoned
- 1991-09-24 CA CA002052165A patent/CA2052165A1/en not_active Abandoned
- 1991-09-26 AT AT91116392T patent/ATE130683T1/de active
- 1991-09-26 EP EP91116392A patent/EP0483512B1/de not_active Expired - Lifetime
- 1991-09-26 DE DE59106940T patent/DE59106940D1/de not_active Expired - Fee Related
- 1991-09-26 ES ES91116392T patent/ES2087940T3/es not_active Expired - Lifetime
- 1991-09-30 JP JP3252443A patent/JPH04248465A/ja active Pending
- 1991-10-04 US US07/771,097 patent/US6210975B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6210975B1 (en) | 2001-04-03 |
AU8472891A (en) | 1992-05-21 |
JPH04248465A (ja) | 1992-09-03 |
DE59106940D1 (de) | 1996-01-04 |
ATE130683T1 (de) | 1995-12-15 |
CA2052165A1 (en) | 1992-05-01 |
EP0483512A1 (de) | 1992-05-06 |
DE4034509A1 (de) | 1992-05-07 |
EP0483512B1 (de) | 1995-11-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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