MX9306234A - Oxindoles y azaoxoindoles 1-substituidos y composiciones farmaceuticas que los contienen. - Google Patents
Oxindoles y azaoxoindoles 1-substituidos y composiciones farmaceuticas que los contienen.Info
- Publication number
- MX9306234A MX9306234A MX9306234A MX9306234A MX9306234A MX 9306234 A MX9306234 A MX 9306234A MX 9306234 A MX9306234 A MX 9306234A MX 9306234 A MX9306234 A MX 9306234A MX 9306234 A MX9306234 A MX 9306234A
- Authority
- MX
- Mexico
- Prior art keywords
- oxydoles
- azaoxoindoles
- substituted
- contain
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/957,152 US5296478A (en) | 1992-10-07 | 1992-10-07 | 1-substituted oxindoles as cognition enhancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9306234A true MX9306234A (es) | 1994-05-31 |
Family
ID=25499153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9306234A MX9306234A (es) | 1992-10-07 | 1993-10-06 | Oxindoles y azaoxoindoles 1-substituidos y composiciones farmaceuticas que los contienen. |
Country Status (7)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744476A (en) * | 1994-06-27 | 1998-04-28 | Interneuron Pharmaceuticals, Inc. | Dopamine D1 agonists for the treatment of dementia |
| DK0813411T3 (da) * | 1995-02-15 | 2002-05-13 | Takeda Chemical Industries Ltd | Anvendelse af vincopetinderivater til hæmning af dannelse eller afsondring af amyloid -protein |
| HRP980429A2 (en) | 1997-08-14 | 1999-06-30 | Jianguo Yin | Crystalline 10,10-bis ((2-fluoro-4-pyridinyl)methyl)-9(10h)-anthracenone and an improved process for preparing the same |
| US20050101929A1 (en) * | 2002-01-17 | 2005-05-12 | Andrew Waksmundzki | Absorbent core with three-dimensional sub-layer |
| MY144968A (en) * | 2005-04-11 | 2011-11-30 | Xenon Pharmaceuticals Inc | Spiro-oxindole compounds and their uses as therapeutic agents |
| MY145694A (en) | 2005-04-11 | 2012-03-30 | Xenon Pharmaceuticals Inc | Spiroheterocyclic compounds and their uses as therapeutic agents |
| AR053713A1 (es) * | 2005-04-20 | 2007-05-16 | Xenon Pharmaceuticals Inc | Compuestos heterociclicos y sus usos como agentes terapeuticos |
| WO2008036282A1 (en) * | 2006-09-18 | 2008-03-27 | The Regents Of The University Of Californina | Upregulating activity or expression of bdnf to mitigate cognitive impairment in asymptomatic huntington's subjects |
| WO2008060789A2 (en) * | 2006-10-12 | 2008-05-22 | Xenon Pharmaceuticals Inc. | Use of spiro-oxindole compounds as therapeutic agents |
| MX2009003875A (es) * | 2006-10-12 | 2009-04-22 | Xenon Pharmaceuticals Inc | Derivados y compuestos relacionados de espiro(furo[3,2-c]piridina- 3,3'-indol)-2' (1'h)ona para el tratamiento de enfermedades mediadas por los canales de sodio, tal como dolor. |
| CN101522685A (zh) * | 2006-10-12 | 2009-09-02 | 泽农医药公司 | 三环螺-吲哚酮衍生物及其作为治疗剂的用途 |
| WO2010045197A1 (en) * | 2008-10-17 | 2010-04-22 | Xenon Pharmaceuticals, Inc. | Spiro-oxindole compounds and their use as therapeutic agents |
| HUE025938T2 (en) | 2008-10-17 | 2016-05-30 | Xenon Pharmaceuticals Inc | Spiro oxindole compounds and their use as therapeutic agents |
| AR077252A1 (es) | 2009-06-29 | 2011-08-10 | Xenon Pharmaceuticals Inc | Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos |
| EP2733145A1 (en) | 2009-10-14 | 2014-05-21 | Xenon Pharmaceuticals Inc. | Synthetic methods for spiro-oxindole compounds |
| US20110086899A1 (en) * | 2009-10-14 | 2011-04-14 | Xenon Pharmaceuticals Inc. | Pharmaceutical compositions for oral administration |
| PH12012501564A1 (en) | 2010-02-26 | 2019-07-17 | Xenon Pharmaceuticals Inc | Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents |
| WO2016127068A1 (en) | 2015-02-05 | 2016-08-11 | Teva Pharmaceuticals International Gmbh | Methods of treating postherpetic neuralgia with a topical formulation of a spiro-oxindole compound |
| CN106565683B (zh) * | 2016-09-30 | 2019-03-12 | 江汉大学 | 一种合成3-羟基氧化吲哚衍生物的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3314954A (en) * | 1964-12-09 | 1967-04-18 | Parke Davis & Co | 1-(diloweralkylamino)-3-(aminoloweralkyl)-3-phenyloxindoles |
| US3595866A (en) * | 1970-01-19 | 1971-07-27 | Parke Davis & Co | 1-amino-3-aminoalkyl-3-phenyloxindole-compounds |
| US5173489A (en) * | 1986-04-10 | 1992-12-22 | The Dupont Merck Pharmaceutical Co. | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers |
| US4760083A (en) * | 1986-04-10 | 1988-07-26 | E. I. Dupont De Nemours & Company | 3,3-disubstituted indolines |
| JPH0747573B2 (ja) * | 1988-06-14 | 1995-05-24 | シェリング・コーポレーション | 抗炎症活性を持つヘテロニ環式化合物 |
| KR930011300B1 (ko) * | 1989-07-25 | 1993-11-29 | 다이호오 야꾸힌 고오교오 가부시끼가이샤 | 옥시인돌유도체 |
| US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
| US5278162A (en) * | 1992-09-18 | 1994-01-11 | The Du Pont Merck Pharmaceutical Company | 3,3'-disubstituted-1,3-dihydro-2H-pyrrolo[2,3-b]heterocyclic-2-one useful in the treatment of cognitive disorders of man |
-
1992
- 1992-10-07 US US07/957,152 patent/US5296478A/en not_active Expired - Fee Related
-
1993
- 1993-10-01 WO PCT/US1993/009183 patent/WO1994007891A1/en active Application Filing
- 1993-10-01 AU AU52928/93A patent/AU5292893A/en not_active Abandoned
- 1993-10-04 IL IL107177A patent/IL107177A0/xx unknown
- 1993-10-05 TW TW082108227A patent/TW268943B/zh active
- 1993-10-06 MX MX9306234A patent/MX9306234A/es unknown
- 1993-10-07 ZA ZA937453A patent/ZA937453B/xx unknown
-
1994
- 1994-02-04 US US08/191,416 patent/US5428035A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU5292893A (en) | 1994-04-26 |
| ZA937453B (en) | 1995-04-07 |
| US5296478A (en) | 1994-03-22 |
| WO1994007891A1 (en) | 1994-04-14 |
| US5428035A (en) | 1995-06-27 |
| IL107177A0 (en) | 1994-01-25 |
| TW268943B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1996-01-21 |
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