MX9304503A - Compuestos antiinflamatorios. - Google Patents
Compuestos antiinflamatorios.Info
- Publication number
- MX9304503A MX9304503A MX9304503A MX9304503A MX9304503A MX 9304503 A MX9304503 A MX 9304503A MX 9304503 A MX9304503 A MX 9304503A MX 9304503 A MX9304503 A MX 9304503A MX 9304503 A MX9304503 A MX 9304503A
- Authority
- MX
- Mexico
- Prior art keywords
- present
- relates
- inflammatory compounds
- lipoxygenase
- cyclooxygenase
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 abstract 2
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 abstract 1
- 102000003820 Lipoxygenases Human genes 0.000 abstract 1
- 108090000128 Lipoxygenases Proteins 0.000 abstract 1
- 102000004005 Prostaglandin-endoperoxide synthases Human genes 0.000 abstract 1
- 108090000459 Prostaglandin-endoperoxide synthases Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940114079 arachidonic acid Drugs 0.000 abstract 1
- 235000021342 arachidonic acid Nutrition 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000013160 medical therapy Methods 0.000 abstract 1
- 230000037353 metabolic pathway Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929215921A GB9215921D0 (en) | 1992-07-27 | 1992-07-27 | Anti-inflammatory compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9304503A true MX9304503A (es) | 1994-04-29 |
Family
ID=10719360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9304503A MX9304503A (es) | 1992-07-27 | 1993-07-26 | Compuestos antiinflamatorios. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0652864A1 (enExample) |
| JP (1) | JPH07509462A (enExample) |
| AU (1) | AU672810B2 (enExample) |
| CA (1) | CA2141214A1 (enExample) |
| GB (1) | GB9215921D0 (enExample) |
| IL (1) | IL106472A0 (enExample) |
| MX (1) | MX9304503A (enExample) |
| TW (1) | TW246670B (enExample) |
| WO (1) | WO1994002448A1 (enExample) |
| ZA (1) | ZA935378B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE154932T1 (de) * | 1993-11-26 | 1997-07-15 | Pfizer | Isoxazolinverbindungen als entzündungshemmende mittel |
| WO1995024192A1 (en) * | 1994-03-09 | 1995-09-14 | Pfizer Inc. | Isoxazoline compounds as 5-lipoxygenase inhibitors |
| JP3322885B2 (ja) * | 1995-02-02 | 2002-09-09 | 日研化学株式会社 | Ｎ−ヒドロキシウレア誘導体 |
| DE69709069T2 (de) | 1996-02-13 | 2002-07-04 | G.D. Searle & Co., Chicago | Zusammensetzungen mit immunosuppressiven wirkungen, welche 5-lipoxygenase-inhibitoren und cyclooxygenase-2-inhibitoren enthalten |
| EP1640003A2 (en) | 1996-02-13 | 2006-03-29 | G.D. SEARLE & CO. | Compositions comprising a Cyclooxygenase-2 Inhibitor and a Leukotriene B4 receptor antagonist |
| DK0880363T3 (da) | 1996-02-13 | 2003-01-20 | Searle & Co | Kombinationer der omfatter en cyclooxygenase-2 hæmmer samt en leukotrien A4 hydrolasehæmmer, som har immunsuppressive virkninger |
| BR9710693A (pt) * | 1996-06-25 | 2000-01-11 | Cephalon Inc | Uso de um derivado de k-252a para o tratamento do nervo central ou periférico e super produção de citoquinona. |
| TR199903287T2 (xx) * | 1997-07-31 | 2000-09-21 | Abbott Laboratories | Matriks metaloproteinazlar�n�n ters hidroksamat inhibit�rleri. |
| US6294573B1 (en) | 1997-08-06 | 2001-09-25 | Abbott Laboratories | Reverse hydroxamate inhibitors of matrix metalloproteinases |
| US6235786B1 (en) | 1997-08-06 | 2001-05-22 | Abbott Laboratories | Reverse hydroxamate inhibitors of matrix metalloproteinases |
| US6288261B1 (en) | 1998-12-18 | 2001-09-11 | Abbott Laboratories | Inhibitors of matrix metalloproteinases |
| WO2000044712A1 (en) * | 1999-01-27 | 2000-08-03 | Abbott Laboratories | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases |
| SE0103325D0 (sv) | 2001-10-04 | 2001-10-04 | Astrazeneca Ab | Novel compounds |
| TW200946105A (en) | 2008-02-07 | 2009-11-16 | Kyorin Seiyaku Kk | Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ215487A (en) * | 1985-03-16 | 1990-01-29 | Wellcome Found | Aryl derivatives, pharmaceutical compositions thereof and preservation of cut flowers |
| PL154186B1 (en) * | 1987-07-15 | 1991-07-31 | Wellcome Found | Method for manufacturing arylic derivatives of the hydroxamic acid |
| AU647177B2 (en) * | 1990-07-25 | 1994-03-17 | Abbott Laboratories | Acetylenic urea derivatives having lipoxygenase inhibitory activity |
| JPH06256285A (ja) * | 1990-12-11 | 1994-09-13 | Pfizer Pharmaceut Co Ltd | ヒドロキサム酸誘導体およびその用途 |
-
1992
- 1992-07-27 GB GB929215921A patent/GB9215921D0/en active Pending
-
1993
- 1993-07-26 ZA ZA935378A patent/ZA935378B/xx unknown
- 1993-07-26 MX MX9304503A patent/MX9304503A/es unknown
- 1993-07-26 IL IL106472A patent/IL106472A0/xx unknown
- 1993-07-26 TW TW082105933A patent/TW246670B/zh active
- 1993-07-27 WO PCT/GB1993/001585 patent/WO1994002448A1/en not_active Ceased
- 1993-07-27 EP EP93917925A patent/EP0652864A1/en not_active Withdrawn
- 1993-07-27 JP JP6504325A patent/JPH07509462A/ja active Pending
- 1993-07-27 AU AU47170/93A patent/AU672810B2/en not_active Ceased
- 1993-07-27 CA CA002141214A patent/CA2141214A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL106472A0 (en) | 1993-11-15 |
| EP0652864A1 (en) | 1995-05-17 |
| WO1994002448A1 (en) | 1994-02-03 |
| JPH07509462A (ja) | 1995-10-19 |
| ZA935378B (en) | 1995-01-26 |
| CA2141214A1 (en) | 1994-02-03 |
| GB9215921D0 (en) | 1992-09-09 |
| AU672810B2 (en) | 1996-10-17 |
| TW246670B (enExample) | 1995-05-01 |
| AU4717093A (en) | 1994-02-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9406979A (pt) | Composto,composicão farmaceutica para tratar uma doenca inflamatória suscetivel de tratamento com um agente anti- inflamatório nao esteroidal processos para tratar uma doenca inflamatória e para preparar um composto sal famacéuticamente aceitável uso de um composto composicão farmaceutica anti-inflamatória nao esteroidal | |
| AR011726A1 (es) | Procedimiento para el tratamiento o prevencion del dolor y procesos y enfermedades inflamatorias, composicion farmaceutica, envase para uso en elmercado en dicho procedimiento | |
| BR9611015A (pt) | Composto, composição farmacêutica e processo para o tratamento de uma doença inflamatória suscetìvel ao tratamento com um agente não-tóxico anti-inflamatório não-esteróide, sal farmaceuticamente aceitável, utilização de um composto | |
| UY29182A1 (es) | "derivados de bencenosulfonamidas sustituídas, composiciones que las contienen, procedimientos de preparación y aplicaciones" | |
| ATE161836T1 (de) | 4-substituierte-2-deoxy-2,3-didehydro alpha-d- neuraminsäure antivirale derivate | |
| ES2233931T3 (es) | Fenilacetato y derivados, solos o en combinacion con otros compuestos, contra estados neoplasicos y otros trastornos. | |
| DE69912606D1 (de) | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol-derivate | |
| ES2166823T3 (es) | Nuevos derivados pirrolicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| AR023423A1 (es) | Derivados de adamantano, procedimientos para su preparacion, composicion farmaceutica, procedimiento para la preparacion de la composicion farmaceutica, yuso de dichos derivados para la manufactura de medicamentos | |
| ES2145922T3 (es) | Compuestos espiro-azabiciclicos utiles en terapia. | |
| AR035533A1 (es) | Uso de por lo menos un inhibidor de la absorcion de los esteroles o sus sales, solvatos, prodrogas farmaceuticamente aceptables o mezclas de los mismos para la preparacion de un medicamento para el tratamiento de la sitosterolemia, composiciones farmaceuticas, el uso de dichas composiciones para la | |
| ES2159382T3 (es) | Compuestos estilbenicos con grupo adamantilo, composiciones que los contienen y utilizaciones. | |
| AR019053A1 (es) | Uso de 2'2'-difluoronucleosidos para la preparacion de un medicamento y composicion farmaceutica y producto farmaceutico que los contienen | |
| EA199700380A1 (ru) | Бициклические ароматические соединения, фармацевтическая и косметическая композиции на их основе и применение косметической композиции | |
| AR005860A1 (es) | Compuestos heterociclicos aromaticos, composiciones farmaceuticas y cosmeticas que los contienen, y su utilización. | |
| BR9713921A (pt) | Composto, composição farmacêutica, processo para tógico capaz de ser modulado através da inibição do fator xa | |
| AR035889A1 (es) | Citrato de 5,7,14-triazatetraciclo[10.3.1.02,11.04,9]hexadeca-2(11),3,5,7,9- pentaeno y composiciones farmaceuticas que la contienen y su uso para la elaboracion de medicamentos | |
| BR0014895A (pt) | Formulação lìquida estável, processo para a preparação da mesma, uso da mesma, uso de polietileno glicol e sal de sódio ou potássio de um inibidor h+, k+-atpase, e, método para tratar doenças gastrointestinais | |
| WO2004100893A3 (en) | Methods for treatment of inflammatory diseases using ct-3 or analogs thereof | |
| ES2087623T3 (es) | Derivados de bencimidazol como agente antimicrobiano contra campylobacter pylon. | |
| UY28943A1 (es) | Nucleósidos de 3-b (beta)-d-ribofuranosiltiazolo(4,5-d) pirimidina y sus usos | |
| DK0658553T3 (da) | Hidtil ukendte polycykliske aromatiske forbindelser, farmaceutiske præparater og kosmetiske sammensætninger indeholdende di | |
| AR018347A1 (es) | 1h-indazoles 1,5 y 3-o-sustituidos y sus sales fisiologicamente tolerables, utilizacion de los mismos para la preparacion de medicamentos, procedimientospara preparar dichos compuestos, las composiciones y preparaciones farmaceuticas que los contienen, y la utilizacion de dichos compuestos y prepara | |
| CA2438799A1 (en) | Preventative of therapeutic agent for inflammatory respiratory tract disease | |
| AR032553A1 (es) | Derivados de alfa-amino-n-hidroxi-acetamida. |