IL106472A0 - Hydroxamic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Hydroxamic acid derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL106472A0 IL106472A0 IL106472A IL10647293A IL106472A0 IL 106472 A0 IL106472 A0 IL 106472A0 IL 106472 A IL106472 A IL 106472A IL 10647293 A IL10647293 A IL 10647293A IL 106472 A0 IL106472 A0 IL 106472A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- acid derivatives
- hydroxamic acid
- Prior art date
Links
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929215921A GB9215921D0 (en) | 1992-07-27 | 1992-07-27 | Anti-inflammatory compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL106472A0 true IL106472A0 (en) | 1993-11-15 |
Family
ID=10719360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL106472A IL106472A0 (en) | 1992-07-27 | 1993-07-26 | Hydroxamic acid derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0652864A1 (enExample) |
| JP (1) | JPH07509462A (enExample) |
| AU (1) | AU672810B2 (enExample) |
| CA (1) | CA2141214A1 (enExample) |
| GB (1) | GB9215921D0 (enExample) |
| IL (1) | IL106472A0 (enExample) |
| MX (1) | MX9304503A (enExample) |
| TW (1) | TW246670B (enExample) |
| WO (1) | WO1994002448A1 (enExample) |
| ZA (1) | ZA935378B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL314605A1 (en) * | 1993-11-26 | 1996-09-16 | Pfizer | Isoxazolin compounds as anti-inflammatory agents |
| EP0749307A1 (en) * | 1994-03-09 | 1996-12-27 | Pfizer Inc. | Isoxazoline compounds as 5-lipoxygenase inhibitors |
| CA2210905A1 (en) * | 1995-02-02 | 1996-08-08 | Nikken Chemicals Co., Ltd. | N-hydroxyurea derivatives |
| ES2243978T3 (es) | 1996-02-13 | 2005-12-01 | G.D. SEARLE & CO. | Composiciones que comprenden un inhibidor de la ciclooxigenasa-2 y un antagonista del receptor de leucotrieno b4. |
| CA2246265A1 (en) | 1996-02-13 | 1997-08-21 | G.D. Searle & Co. | Combinations having immunosuppressive effects, containing cyclooxygenase-2-inhibitors and 5-lipoxygenase inhibitors |
| PT880363E (pt) | 1996-02-13 | 2002-12-31 | Searle & Co | Combinacoes com efeitos imunossupressores cntendo um inibidor da ciclooxigenase-2 e um inibidor da hidrolase do leucotrieno a4 |
| US6184217B1 (en) * | 1996-06-25 | 2001-02-06 | Cephalon, Inc. | Use of K-252a derivative |
| NZ501166A (en) * | 1997-07-31 | 2001-12-21 | Abbott Lab | Reverse hydroxamate-containing compounds and their use as inhibitors of matrix metalloproteinases |
| US6294573B1 (en) | 1997-08-06 | 2001-09-25 | Abbott Laboratories | Reverse hydroxamate inhibitors of matrix metalloproteinases |
| US6235786B1 (en) | 1997-08-06 | 2001-05-22 | Abbott Laboratories | Reverse hydroxamate inhibitors of matrix metalloproteinases |
| US6288261B1 (en) | 1998-12-18 | 2001-09-11 | Abbott Laboratories | Inhibitors of matrix metalloproteinases |
| WO2000044712A1 (en) * | 1999-01-27 | 2000-08-03 | Abbott Laboratories | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases |
| SE0103325D0 (sv) * | 2001-10-04 | 2001-10-04 | Astrazeneca Ab | Novel compounds |
| US8476305B2 (en) | 2008-02-07 | 2013-07-02 | Kyorin Pharmaceutical Co., Ltd. | Therapeutic agent or prophylactic agent for inflammatory bowel disease comprising amino alcohol derivative as active ingredient |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU201300B (en) * | 1985-03-16 | 1990-10-28 | Wellcome Found | Process for production of derivatives of aryl and medical compositions containing them as active substance |
| PL154186B1 (en) * | 1987-07-15 | 1991-07-31 | Wellcome Found | Method for manufacturing arylic derivatives of the hydroxamic acid |
| JPH0819069B2 (ja) * | 1990-07-25 | 1996-02-28 | アボツト・ラボラトリーズ | リポキシゲナーゼ阻害活性を有するアセチレン誘導体 |
| JPH06256285A (ja) * | 1990-12-11 | 1994-09-13 | Pfizer Pharmaceut Co Ltd | ヒドロキサム酸誘導体およびその用途 |
-
1992
- 1992-07-27 GB GB929215921A patent/GB9215921D0/en active Pending
-
1993
- 1993-07-26 MX MX9304503A patent/MX9304503A/es unknown
- 1993-07-26 TW TW082105933A patent/TW246670B/zh active
- 1993-07-26 IL IL106472A patent/IL106472A0/xx unknown
- 1993-07-26 ZA ZA935378A patent/ZA935378B/xx unknown
- 1993-07-27 WO PCT/GB1993/001585 patent/WO1994002448A1/en not_active Ceased
- 1993-07-27 AU AU47170/93A patent/AU672810B2/en not_active Ceased
- 1993-07-27 EP EP93917925A patent/EP0652864A1/en not_active Withdrawn
- 1993-07-27 JP JP6504325A patent/JPH07509462A/ja active Pending
- 1993-07-27 CA CA002141214A patent/CA2141214A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU4717093A (en) | 1994-02-14 |
| WO1994002448A1 (en) | 1994-02-03 |
| JPH07509462A (ja) | 1995-10-19 |
| MX9304503A (es) | 1994-04-29 |
| CA2141214A1 (en) | 1994-02-03 |
| GB9215921D0 (en) | 1992-09-09 |
| EP0652864A1 (en) | 1995-05-17 |
| AU672810B2 (en) | 1996-10-17 |
| ZA935378B (en) | 1995-01-26 |
| TW246670B (enExample) | 1995-05-01 |
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