MX9303601A - Factores biologicos con actividad biologica mejor ada, a base de copolimeros de polioximetileno-oxietileno en conjuncion con biomoleculas. - Google Patents

Factores biologicos con actividad biologica mejor ada, a base de copolimeros de polioximetileno-oxietileno en conjuncion con biomoleculas.

Info

Publication number
MX9303601A
MX9303601A MX9303601A MX9303601A MX9303601A MX 9303601 A MX9303601 A MX 9303601A MX 9303601 A MX9303601 A MX 9303601A MX 9303601 A MX9303601 A MX 9303601A MX 9303601 A MX9303601 A MX 9303601A
Authority
MX
Mexico
Prior art keywords
biological
polyoxymethylene
biomolecules
conjunction
biological activity
Prior art date
Application number
MX9303601A
Other languages
English (en)
Inventor
Colin G Pitt
Wayne Hendren
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX9303601A publication Critical patent/MX9303601A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Polyethers (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

La presente invención se relaciona con factores biológicos con actividad biológica aumentada preparados por el enlace covalente de una biomolécula a una o más cadenas de un polímero sintético, en donde el polímero sintético se deriva a partir de parte de la estructura del oximetileno-oxietileno.
MX9303601A 1992-06-17 1993-06-16 Factores biologicos con actividad biologica mejor ada, a base de copolimeros de polioximetileno-oxietileno en conjuncion con biomoleculas. MX9303601A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90003792A 1992-06-17 1992-06-17

Publications (1)

Publication Number Publication Date
MX9303601A true MX9303601A (es) 1994-06-30

Family

ID=25411886

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9303601A MX9303601A (es) 1992-06-17 1993-06-16 Factores biologicos con actividad biologica mejor ada, a base de copolimeros de polioximetileno-oxietileno en conjuncion con biomoleculas.

Country Status (10)

Country Link
US (1) US5476653A (es)
EP (1) EP0576192A3 (es)
JP (1) JPH07508727A (es)
CN (1) CN1083822A (es)
AU (1) AU4538993A (es)
CA (1) CA2138277A1 (es)
IL (1) IL105918A0 (es)
MX (1) MX9303601A (es)
WO (1) WO1993025212A1 (es)
ZA (1) ZA933926B (es)

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Also Published As

Publication number Publication date
WO1993025212A1 (en) 1993-12-23
CA2138277A1 (en) 1993-12-23
AU4538993A (en) 1994-01-04
EP0576192A2 (en) 1993-12-29
EP0576192A3 (en) 1994-05-18
CN1083822A (zh) 1994-03-16
JPH07508727A (ja) 1995-09-28
IL105918A0 (en) 1993-10-20
US5476653A (en) 1995-12-19
ZA933926B (en) 1994-01-03

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