MX9301675A - Composiciones que contienen peptidos para inducir tolerancia de las celulas t a un antigeno. - Google Patents
Composiciones que contienen peptidos para inducir tolerancia de las celulas t a un antigeno.Info
- Publication number
- MX9301675A MX9301675A MX9301675A MX9301675A MX9301675A MX 9301675 A MX9301675 A MX 9301675A MX 9301675 A MX9301675 A MX 9301675A MX 9301675 A MX9301675 A MX 9301675A MX 9301675 A MX9301675 A MX 9301675A
- Authority
- MX
- Mexico
- Prior art keywords
- antigen
- induce
- compositions containing
- cell tolerance
- containing peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Abstract
La presente invención se basa en el descubrimiento de que la administración subcutánea de un péptido, que contiene al menos un epitopo de célula T de un alérgeno proteico o de otro antígeno proteico, da como resultado una tolerancia de la célula T, luego de una exposición posterior, al alérgeno u otro antígeno. Los péptidos útiles para inducir tolerancia en un mamífero, como en el humano, mediante administración subcutánea u otras rutas de administración, se encuentran dentro de los alcances de la invención.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85731192A | 1992-03-25 | 1992-03-25 | |
US88471892A | 1992-05-15 | 1992-05-15 | |
US611693A | 1993-01-15 | 1993-01-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9301675A true MX9301675A (es) | 1993-12-01 |
Family
ID=27358042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9301675A MX9301675A (es) | 1992-03-25 | 1993-03-25 | Composiciones que contienen peptidos para inducir tolerancia de las celulas t a un antigeno. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0672134A1 (es) |
JP (1) | JPH07505365A (es) |
AU (1) | AU677954B2 (es) |
CA (1) | CA2132873C (es) |
IL (1) | IL105153A (es) |
MX (1) | MX9301675A (es) |
WO (1) | WO1993019178A2 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6019972A (en) | 1989-11-03 | 2000-02-01 | Immulogic Pharmaceutical Corporation | Peptides of human T cell reactive feline protein (TRFP) |
US6120769A (en) * | 1989-11-03 | 2000-09-19 | Immulogic Pharmaceutical Corporation | Human T cell reactive feline protein (TRFP) isolated from house dust and uses therefor |
CA2164326A1 (en) * | 1993-06-02 | 1994-12-08 | Wayne Robert Thomas | Cryptic peptides for use in inducing immunologic tolerance |
US6759234B1 (en) * | 1994-09-02 | 2004-07-06 | Immulogic Pharmaceutical Corporation | Compositions and methods for administering to humans, peptides capable of down regulating an antigen specific immune response |
WO1996012737A2 (en) * | 1994-10-25 | 1996-05-02 | Immulogic Pharmaceutical Corporation | Compositions and treatment for multiple sclerosis |
US6379670B1 (en) | 1994-11-18 | 2002-04-30 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein |
US6251396B1 (en) | 1994-11-18 | 2001-06-26 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein |
JP4340329B2 (ja) | 1996-03-21 | 2009-10-07 | サーカッシア リミテッド | 潜在ペプチドならびにそれらの同定方法 |
EP0960887B1 (en) | 1996-06-14 | 2007-04-25 | Meiji Dairies Corporation | T cell epitope peptides |
US6780416B1 (en) | 2000-02-18 | 2004-08-24 | Ecole Polytechnique Federale De Lausanne | Bee venom polypeptides and methods of use thereof |
US7923209B2 (en) | 2003-03-14 | 2011-04-12 | Anergis, S.A. | Allergen peptide fragments and use thereof |
AT503690A1 (de) * | 2006-06-09 | 2007-12-15 | Biomay Ag | Hypoallergene moleküle |
EP3269379A1 (en) | 2008-11-30 | 2018-01-17 | Immusant, Inc. | Compositions and methods for treatment of celiac disease |
CA2923822A1 (en) | 2013-09-10 | 2015-03-19 | Immusant, Inc. | Dosage of a gluten peptide composition |
US10370718B2 (en) | 2014-09-29 | 2019-08-06 | Immusant, Inc. | Use of HLA genetic status to assess or select treatment of celiac disease |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5328991A (en) * | 1989-11-03 | 1994-07-12 | Immulogic Pharmaceutical Corp. | Preparation of alkali-modified cat dander allergen (Fel d I) for immunotherapeutic purposes |
ATE216401T1 (de) * | 1989-11-03 | 2002-05-15 | Immulogic Pharma Corp | Aus hausstaub isoliertes t-zellreaktives katzenprotein, und dessen verwendungen |
ES2300100T3 (es) * | 1991-10-16 | 2008-06-01 | Merck Patent Gmbh | Metodos para el diseño de peptidos de epitodo recombinado. |
-
1993
- 1993-03-24 IL IL10515393A patent/IL105153A/en not_active IP Right Cessation
- 1993-03-25 MX MX9301675A patent/MX9301675A/es unknown
- 1993-03-25 JP JP5516715A patent/JPH07505365A/ja active Pending
- 1993-03-25 EP EP93908385A patent/EP0672134A1/en not_active Withdrawn
- 1993-03-25 WO PCT/US1993/002462 patent/WO1993019178A2/en not_active Application Discontinuation
- 1993-03-25 AU AU39226/93A patent/AU677954B2/en not_active Expired
- 1993-03-25 CA CA2132873A patent/CA2132873C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH07505365A (ja) | 1995-06-15 |
WO1993019178A3 (en) | 1993-11-25 |
AU3922693A (en) | 1993-10-21 |
IL105153A (en) | 1999-12-22 |
AU677954B2 (en) | 1997-05-15 |
WO1993019178A2 (en) | 1993-09-30 |
EP0672134A1 (en) | 1995-09-20 |
CA2132873A1 (en) | 1993-09-30 |
CA2132873C (en) | 2012-10-16 |
IL105153A0 (en) | 1993-07-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9301675A (es) | Composiciones que contienen peptidos para inducir tolerancia de las celulas t a un antigeno. | |
MX9205985A (es) | Epitopes de las celulas t de los alergenos principales del genero dermatophagoides y composiciones farmaceuticas que los contienen. | |
CY1117387T1 (el) | ΜΟΝΟΚΛΩΝΙΚΑ ΑΝΤΙΣΩΜΑΤΑ Ν-11 ΔΙΑΣΠΑΣΜΕΝΟΥ β-ΑΜΥΛΟΕΙΔΟΥΣ, ΣΥΝΘΕΣΕΙΣ, ΜΕΘΟΔΟΙ ΚΑΙ ΧΡΗΣΕΙΣ | |
ES2180754T3 (es) | Compuestos y metodos para la deteccion de infeccion por t. cruzi. | |
ES2164251T3 (es) | Vacuna que comprende un conjugado antigeno polisacarido-proteina transportadora y proteina transportadora libre. | |
BR0016022A (pt) | Vacina para a prevenção e tratamento da doença de alzheimer e doenças relacionadas ao amilóide | |
AR003427A1 (es) | Péptidos relacionados con dolastatina, procedimiento para prepararlos, composiciones farmacéuticas que los contienen y el uso de los mismos para la preparación de dichas composiciones farmacéuticas. | |
ES2173284T3 (es) | Agentes endoparasicitidas. | |
ES2136654T3 (es) | Herramientas para el diagnostico y tratamiento de la enfermedad de alzheimer. | |
ES2075050T3 (es) | Peptidos que tienen actividad cooperadora de celulas t. | |
DE59309786D1 (de) | Enniatine und enniatinderivate zur bekämpfung von endoparasiten | |
ES2166166T3 (es) | Analogos de peptido lh-rh, sus usos y composiciones farmaceuticas que los contienen. | |
ES2134197T3 (es) | Vacunas contra el virus del herpes simplex vp16. | |
AR002949A1 (es) | Análogos del peptido p277 y composiciónes farmaceuticas y preparaciónes que los comprenden para el tratamiento o diagnostico de diabetes y un equipo para diagnosticar. | |
ES2118939T3 (es) | Peptido para el diagnostico e inmunizacion contra la infeccion con t.cruzi. | |
ES2163631T3 (es) | Un peptido mejorado, composicion inmunogenica y vacuna o preparacion medica, un procedimiento para inmunizar a los animales contra la hormona lhrh, analogos del peptido lhrh repetidos en tandem y su uso como vacuna. | |
ES2044976T3 (es) | Preparados activos frente a infecciones por pseudomonas aeruginosa y procedimiento para su fabricacion. | |
MX9302024A (es) | Epitopes de celula t de los alergenos principales de ambrosina artemisfolia. | |
ES2134474T3 (es) | Peptidos utilizados como agentes terapeuticos para el tratamiento de enfermedades autoinmunitarias. | |
ES2118720T3 (es) | Produccion y utilizacion de agentes antihelminticos e inmunogenos protectores. | |
ES2140672T3 (es) | Compuestos biciclicos sustituidos, fusionados y puentes utilizados como agentes terapeuticos. | |
MX9401172A (es) | Derivados fluorados de 4-aminoandrostadienona, procesamiento para su preparacion y composiciones farmaceuticas que los contienen. | |
NO894880L (no) | Fremgangsmaate for fremstilling av antikoagulerende peptider. | |
ES2085163T3 (es) | Vacunas contra los parasitos metazoos. | |
ES2094228T3 (es) | Peptidos anticoagulantes. |