ES2180754T3 - Compuestos y metodos para la deteccion de infeccion por t. cruzi. - Google Patents
Compuestos y metodos para la deteccion de infeccion por t. cruzi.Info
- Publication number
- ES2180754T3 ES2180754T3 ES96910433T ES96910433T ES2180754T3 ES 2180754 T3 ES2180754 T3 ES 2180754T3 ES 96910433 T ES96910433 T ES 96910433T ES 96910433 T ES96910433 T ES 96910433T ES 2180754 T3 ES2180754 T3 ES 2180754T3
- Authority
- ES
- Spain
- Prior art keywords
- cruzi
- compounds
- infection
- detection
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 208000015181 infectious disease Diseases 0.000 title abstract 4
- 238000001514 detection method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 206010001935 American trypanosomiasis Diseases 0.000 abstract 1
- 208000024699 Chagas disease Diseases 0.000 abstract 1
- 241000222722 Leishmania <genus> Species 0.000 abstract 1
- 241000223109 Trypanosoma cruzi Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
SE DESCRIBEN LOS COMPUESTOS Y METODOS PARA EL DIAGNOSTICO DE LA INFECCION CON TRIPANOSOMA CRUZI O PARA LA DETECCION DE LA INFECCION CON T. CRUZI O LEISHMANIA. LOS COMPUESTOS DESCRITOS SON POLIPEPTIDOS O ANTICUERPOS PARA LOS MISMOS QUE CONTIENEN UNO O MAS EPITOPOS ANTIGENICOS DE LAS PROTEINAS DE T. CRUZI. LOS COMPUESTOS SON UTILES EN VARIOS INMUNOENSAYOS PARA LA DETECCION DE LA INFECCION CON T. CRUZI. LOS COMPUESTOS POLIPEPTIDICOS SON ADEMAS UTILES EN LAS VACUNAS Y EN LAS COMPOSICIONES FARMACEUTICAS PARA LA PREVENCION DE LA ENFERMEDAD DE CHAGAS EN INDIVIDUOS EXPUESTOS A T. CRUZI.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/403,379 US5756662A (en) | 1995-03-14 | 1995-03-14 | Compounds and methods for the detection of T. cruzi infection |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2180754T3 true ES2180754T3 (es) | 2003-02-16 |
Family
ID=23595554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96910433T Expired - Lifetime ES2180754T3 (es) | 1995-03-14 | 1996-03-12 | Compuestos y metodos para la deteccion de infeccion por t. cruzi. |
Country Status (13)
Country | Link |
---|---|
US (2) | US5756662A (es) |
EP (1) | EP0815450B1 (es) |
JP (1) | JPH11502923A (es) |
AR (1) | AR002282A1 (es) |
AT (1) | ATE220797T1 (es) |
AU (1) | AU5362696A (es) |
BR (1) | BR9607531A (es) |
CA (1) | CA2215104A1 (es) |
DE (1) | DE69622385T2 (es) |
DK (1) | DK0815450T3 (es) |
ES (1) | ES2180754T3 (es) |
PT (1) | PT815450E (es) |
WO (1) | WO1996029605A2 (es) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5756662A (en) * | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
BR9503451A (pt) * | 1995-07-26 | 1997-09-30 | Mendes Rodolfo Pereira | Processo de preparação de um antígeno derivado de um mocroorganismo causador de doença infecciosa e/ou parasitária processo de preparação de um antígeno de T cruzi antígeno derivado de midroorganismo causador de doença infecciosa e/ou parasitária antígeno derivado de T cruzi causador de doença de chagas composição a base de um antígeno derivado de microorganismo causador de doença infecciosa e/ou parasitária composição a base de antígeno de T cruzi utilização do antígeno derivado de microorganismo causador de doença infecciosa e/ou parasitária em testes sorológicos e vacinas utilização de antigeno derivado de T cruzi causador de doença de chagas em teste sorológico e vacinas processo para detecção de anticorpos anti antigeno de microorganismo causador de doença infecciosa e/ou parasitária e kit para sorodiagnóstico confirmatório para doença infecciosa e/ou parasitária |
US6228372B1 (en) | 1997-04-15 | 2001-05-08 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
US6419933B1 (en) | 1995-11-14 | 2002-07-16 | Corixa Corporation | Compounds and methods for the detection and prevention of T.cruzi infection |
US6054135A (en) * | 1996-11-14 | 2000-04-25 | Corixa | Compounds and methods for the detection and prevention of T. cruzi infection |
US5916572A (en) * | 1995-11-14 | 1999-06-29 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
BR9808251B1 (pt) | 1997-03-11 | 2012-09-04 | vacina, e, uso de uma proteìna isolada ou recombinante ou fragmento antigênico da mesma. | |
US6699722B2 (en) | 2000-04-14 | 2004-03-02 | A-Fem Medical Corporation | Positive detection lateral-flow apparatus and method for small and large analytes |
JP2006518184A (ja) * | 2002-09-20 | 2006-08-10 | アクゾ・ノベル・エヌ・ベー | 弱毒寄生虫生ワクチン |
US20050191685A1 (en) | 2004-02-24 | 2005-09-01 | Innogenetics N.V. | Method for determining the risk of developing a neurological disease |
US7888135B2 (en) * | 2004-04-23 | 2011-02-15 | University Of Georgia Research Foundation, Inc. | Diagnostic assay for Trypanosoma cruzi infection |
RU2551782C2 (ru) | 2005-12-12 | 2015-05-27 | Ац Иммуне Са | Специфические в отношении амилоида бета (а бета) 1-42 моноклональные антитела, обладающие терапевтическими свойствами |
US7833534B2 (en) * | 2006-04-10 | 2010-11-16 | Infectious Disease Research Institute | Compounds and methods for diagnosis and treatment of leishmaniasis |
LT2468770T (lt) | 2006-07-14 | 2018-05-25 | Ac Immune S.A. | Humanizuotas antikūnas prieš beta amiloidą |
PL2046833T3 (pl) | 2006-07-14 | 2014-01-31 | Ac Immune Sa | Humanizowane przeciwciało przeciw amyloidowi beta |
US7749717B2 (en) * | 2006-10-19 | 2010-07-06 | Abbott Laboratories | Methods for the detection and diagnosis of Trypanosoma cruzi infection |
SG173409A1 (en) | 2006-11-24 | 2011-08-29 | Ac Immune Sa | N-(methyl)-1h-pyrazol-3-amine, n-(methyl)-pyridin-2-amine and n-(methyl)-thiazol-2-amine derivatives for the treatment of diseases associated with amyloid or amyloid-like proteins, like e.g. alzheimers |
KR20150055103A (ko) | 2007-06-12 | 2015-05-20 | 에이씨 이뮨 에스.에이. | 아밀로이드 베타에 대해 인간화된 항체 |
US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
KR101600095B1 (ko) | 2007-06-12 | 2016-03-07 | 에이씨 이뮨 에스.에이. | 모노클로널 항 베타 아밀로이드 항체 |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
CA2700000A1 (en) * | 2007-07-30 | 2009-02-05 | Rick L. Tarleton | Diagnostic assay for trypanosoma cruzi infection |
CA2701790A1 (en) | 2007-10-05 | 2009-04-16 | Ac Immune S.A. | Use of humanized anti-beta-amyloid antibody in ocular diseases |
US9403902B2 (en) | 2007-10-05 | 2016-08-02 | Ac Immune S.A. | Methods of treating ocular disease associated with amyloid-beta-related pathology using an anti-amyloid-beta antibody |
JP5611834B2 (ja) | 2007-12-27 | 2014-10-22 | アボット・ラボラトリーズAbbott Laboratories | 抗T.cruzi抗体及び使用方法 |
WO2009158729A2 (en) * | 2008-06-27 | 2009-12-30 | The Infectious Disease Research Institute Inc. | Compounds and methods for diagnosis and treatment of chagas disease |
ES2628743T3 (es) | 2008-07-03 | 2017-08-03 | Infectious Disease Research Institute | Proteínas de fusión y su uso en el diagnóstico y tratamiento de la leishmaniasis |
EP2311823A1 (en) | 2009-10-15 | 2011-04-20 | AC Immune S.A. | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
DK2558446T5 (da) | 2010-04-16 | 2019-12-09 | Ac Immune Sa | Nye forbindelser til behandling af sygdomme associerede med amyloid- eller amyloidlignende proteiner |
US20110256064A1 (en) | 2010-04-16 | 2011-10-20 | Ac Immune, S.A. | Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins |
JP6081356B2 (ja) | 2010-07-30 | 2017-02-15 | エーシー イミューン エス.エー. | 安全で機能的なヒト化抗βアミロイド抗体 |
MY164376A (en) | 2010-10-07 | 2017-12-15 | Univ Leuven Kath | Phosphospecific antibodies recognizing tau |
WO2012055933A1 (en) | 2010-10-26 | 2012-05-03 | Ac Immune S.A. | Liposome-based construct comprising a peptide modified through hydrophobic moieties |
AR092779A1 (es) | 2011-10-07 | 2015-05-06 | Ac Immune Sa | Composicon farmaceutica que comprende anticuerpos que se unen a conformeros de proteinas tau |
CA2869438C (en) | 2012-04-05 | 2021-08-17 | Ac Immune S.A. | Humanized tau antibody |
EP3505534A1 (en) | 2012-06-08 | 2019-07-03 | Sutro Biopharma, Inc. | Antibodies comprising sitespecific nonnatural amino acid residues, methods of their preparation and methods of their use |
ES2611788T3 (es) | 2012-06-26 | 2017-05-10 | Sutro Biopharma, Inc. | Proteínas de Fc modificadas que comprenden residuos de aminoácidos no naturales específicos del sitio, conjugados de las mismas, métodos para su preparación y métodos para su uso |
BR112015004022B1 (pt) | 2012-08-31 | 2023-04-25 | Sutro Biopharma, Inc | Aminoácidos modificados compreendendo um grupo azido |
JP6568514B2 (ja) | 2013-03-15 | 2019-08-28 | エーシー イミューン エス.エー. | 抗タウ抗体及び使用方法 |
US9764039B2 (en) | 2013-07-10 | 2017-09-19 | Sutro Biopharma, Inc. | Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use |
US10858426B2 (en) | 2013-09-05 | 2020-12-08 | Ab2 Bio Sa | IL-18 binding protein (IL-18BP) in inflammatory diseases |
WO2015054658A1 (en) | 2013-10-11 | 2015-04-16 | Sutro Biopharma, Inc. | Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use |
SG11201706879UA (en) | 2015-03-05 | 2017-09-28 | Ab2 Bio Sa | Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases |
WO2017218698A1 (en) | 2016-06-15 | 2017-12-21 | Sutro Biopharma, Inc. | Antibodies with engineered ch2 domains, compositions thereof and methods of using the same |
GB201807367D0 (en) | 2018-05-04 | 2018-06-20 | Univ Newcastle | Biomarker |
WO2021178597A1 (en) | 2020-03-03 | 2021-09-10 | Sutro Biopharma, Inc. | Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use |
US20230173021A1 (en) | 2020-05-06 | 2023-06-08 | Ab2 Bio Sa | IL-18 Binding Protein (IL-18BP) In Respiratory Diseases |
EP3943097A1 (en) | 2020-07-24 | 2022-01-26 | AB2 Bio SA | Car-t cell therapy |
WO2023166206A1 (en) | 2022-03-04 | 2023-09-07 | Ab2 Bio Sa | Il-18 binding protein (il-18bp) in the treatment of vexas |
WO2024006563A1 (en) | 2022-07-01 | 2024-01-04 | Sutro Biopharma, Inc. | Il-12 mutants with reduced toxicity, compositions thereof and methods of using the same |
WO2024044780A1 (en) | 2022-08-26 | 2024-02-29 | Sutro Biopharma, Inc. | Interleukin-18 variants and uses thereof |
WO2024098023A2 (en) | 2022-11-04 | 2024-05-10 | Sutro Biopharma, Inc. | Interferon alpha polypeptides and conjugates |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4870006A (en) * | 1986-07-24 | 1989-09-26 | Codon | Antigenic material for a chagas' disease detection system |
WO1990002564A1 (en) * | 1988-09-12 | 1990-03-22 | Codon | Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi |
BR9006039A (pt) * | 1990-11-28 | 1992-07-14 | Fundacao Oswaldo Cruz | Processo para preparacao de antigeno conjugado a atividade enzimatica,composicao a base de conjugado enzima-antigeno para utilizacao em diagnostico imunologico e kits de diagnostico imunologico da doenca de chagas a base da dita composicao,para aplicacao individual e/ou em inqueritos epidemiologicos |
US5304371A (en) * | 1992-02-14 | 1994-04-19 | Lasys Corporation | Peptide for diagnosing and immunizing against T. cruzi infection |
TW246717B (es) * | 1992-07-10 | 1995-05-01 | Abbott Lab | |
US5756662A (en) * | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
-
1995
- 1995-03-14 US US08/403,379 patent/US5756662A/en not_active Expired - Lifetime
-
1996
- 1996-03-12 ES ES96910433T patent/ES2180754T3/es not_active Expired - Lifetime
- 1996-03-12 DE DE69622385T patent/DE69622385T2/de not_active Expired - Fee Related
- 1996-03-12 AT AT96910433T patent/ATE220797T1/de not_active IP Right Cessation
- 1996-03-12 DK DK96910433T patent/DK0815450T3/da active
- 1996-03-12 BR BR9607531A patent/BR9607531A/pt not_active Application Discontinuation
- 1996-03-12 EP EP96910433A patent/EP0815450B1/en not_active Expired - Lifetime
- 1996-03-12 PT PT96910433T patent/PT815450E/pt unknown
- 1996-03-12 JP JP8528478A patent/JPH11502923A/ja active Pending
- 1996-03-12 AU AU53626/96A patent/AU5362696A/en not_active Abandoned
- 1996-03-12 WO PCT/US1996/003380 patent/WO1996029605A2/en active IP Right Grant
- 1996-03-12 CA CA002215104A patent/CA2215104A1/en not_active Abandoned
- 1996-03-15 AR ARP960101762A patent/AR002282A1/es not_active Application Discontinuation
-
1997
- 1997-09-15 US US08/929,414 patent/US5942403A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU5362696A (en) | 1996-10-08 |
DE69622385T2 (de) | 2003-03-06 |
WO1996029605A3 (en) | 1996-11-21 |
BR9607531A (pt) | 1998-01-06 |
WO1996029605A2 (en) | 1996-09-26 |
EP0815450B1 (en) | 2002-07-17 |
US5942403A (en) | 1999-08-24 |
ATE220797T1 (de) | 2002-08-15 |
AR002282A1 (es) | 1998-03-11 |
PT815450E (pt) | 2002-12-31 |
CA2215104A1 (en) | 1996-09-26 |
JPH11502923A (ja) | 1999-03-09 |
EP0815450A2 (en) | 1998-01-07 |
MX9707020A (es) | 1998-06-30 |
US5756662A (en) | 1998-05-26 |
DK0815450T3 (da) | 2002-10-28 |
DE69622385D1 (de) | 2002-08-22 |
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