ES2180754T3 - Compuestos y metodos para la deteccion de infeccion por t. cruzi. - Google Patents

Compuestos y metodos para la deteccion de infeccion por t. cruzi.

Info

Publication number
ES2180754T3
ES2180754T3 ES96910433T ES96910433T ES2180754T3 ES 2180754 T3 ES2180754 T3 ES 2180754T3 ES 96910433 T ES96910433 T ES 96910433T ES 96910433 T ES96910433 T ES 96910433T ES 2180754 T3 ES2180754 T3 ES 2180754T3
Authority
ES
Spain
Prior art keywords
cruzi
compounds
infection
detection
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96910433T
Other languages
English (en)
Inventor
Steven G Reed
Raymond L Houghton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corixa Corp
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Application granted granted Critical
Publication of ES2180754T3 publication Critical patent/ES2180754T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905Protozoa
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

SE DESCRIBEN LOS COMPUESTOS Y METODOS PARA EL DIAGNOSTICO DE LA INFECCION CON TRIPANOSOMA CRUZI O PARA LA DETECCION DE LA INFECCION CON T. CRUZI O LEISHMANIA. LOS COMPUESTOS DESCRITOS SON POLIPEPTIDOS O ANTICUERPOS PARA LOS MISMOS QUE CONTIENEN UNO O MAS EPITOPOS ANTIGENICOS DE LAS PROTEINAS DE T. CRUZI. LOS COMPUESTOS SON UTILES EN VARIOS INMUNOENSAYOS PARA LA DETECCION DE LA INFECCION CON T. CRUZI. LOS COMPUESTOS POLIPEPTIDICOS SON ADEMAS UTILES EN LAS VACUNAS Y EN LAS COMPOSICIONES FARMACEUTICAS PARA LA PREVENCION DE LA ENFERMEDAD DE CHAGAS EN INDIVIDUOS EXPUESTOS A T. CRUZI.
ES96910433T 1995-03-14 1996-03-12 Compuestos y metodos para la deteccion de infeccion por t. cruzi. Expired - Lifetime ES2180754T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/403,379 US5756662A (en) 1995-03-14 1995-03-14 Compounds and methods for the detection of T. cruzi infection

Publications (1)

Publication Number Publication Date
ES2180754T3 true ES2180754T3 (es) 2003-02-16

Family

ID=23595554

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96910433T Expired - Lifetime ES2180754T3 (es) 1995-03-14 1996-03-12 Compuestos y metodos para la deteccion de infeccion por t. cruzi.

Country Status (13)

Country Link
US (2) US5756662A (es)
EP (1) EP0815450B1 (es)
JP (1) JPH11502923A (es)
AR (1) AR002282A1 (es)
AT (1) ATE220797T1 (es)
AU (1) AU5362696A (es)
BR (1) BR9607531A (es)
CA (1) CA2215104A1 (es)
DE (1) DE69622385T2 (es)
DK (1) DK0815450T3 (es)
ES (1) ES2180754T3 (es)
PT (1) PT815450E (es)
WO (1) WO1996029605A2 (es)

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US5756662A (en) * 1995-03-14 1998-05-26 Corixa Corporation Compounds and methods for the detection of T. cruzi infection
BR9503451A (pt) * 1995-07-26 1997-09-30 Mendes Rodolfo Pereira Processo de preparação de um antígeno derivado de um mocroorganismo causador de doença infecciosa e/ou parasitária processo de preparação de um antígeno de T cruzi antígeno derivado de midroorganismo causador de doença infecciosa e/ou parasitária antígeno derivado de T cruzi causador de doença de chagas composição a base de um antígeno derivado de microorganismo causador de doença infecciosa e/ou parasitária composição a base de antígeno de T cruzi utilização do antígeno derivado de microorganismo causador de doença infecciosa e/ou parasitária em testes sorológicos e vacinas utilização de antigeno derivado de T cruzi causador de doença de chagas em teste sorológico e vacinas processo para detecção de anticorpos anti antigeno de microorganismo causador de doença infecciosa e/ou parasitária e kit para sorodiagnóstico confirmatório para doença infecciosa e/ou parasitária
US6228372B1 (en) 1997-04-15 2001-05-08 Corixa Corporation Compounds and methods for the detection and prevention of T. cruzi infection
US6419933B1 (en) 1995-11-14 2002-07-16 Corixa Corporation Compounds and methods for the detection and prevention of T.cruzi infection
US6054135A (en) * 1996-11-14 2000-04-25 Corixa Compounds and methods for the detection and prevention of T. cruzi infection
US5916572A (en) * 1995-11-14 1999-06-29 Corixa Corporation Compounds and methods for the detection and prevention of T. cruzi infection
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US20050191685A1 (en) 2004-02-24 2005-09-01 Innogenetics N.V. Method for determining the risk of developing a neurological disease
US7888135B2 (en) * 2004-04-23 2011-02-15 University Of Georgia Research Foundation, Inc. Diagnostic assay for Trypanosoma cruzi infection
RU2551782C2 (ru) 2005-12-12 2015-05-27 Ац Иммуне Са Специфические в отношении амилоида бета (а бета) 1-42 моноклональные антитела, обладающие терапевтическими свойствами
US7833534B2 (en) * 2006-04-10 2010-11-16 Infectious Disease Research Institute Compounds and methods for diagnosis and treatment of leishmaniasis
LT2468770T (lt) 2006-07-14 2018-05-25 Ac Immune S.A. Humanizuotas antikūnas prieš beta amiloidą
PL2046833T3 (pl) 2006-07-14 2014-01-31 Ac Immune Sa Humanizowane przeciwciało przeciw amyloidowi beta
US7749717B2 (en) * 2006-10-19 2010-07-06 Abbott Laboratories Methods for the detection and diagnosis of Trypanosoma cruzi infection
SG173409A1 (en) 2006-11-24 2011-08-29 Ac Immune Sa N-(methyl)-1h-pyrazol-3-amine, n-(methyl)-pyridin-2-amine and n-(methyl)-thiazol-2-amine derivatives for the treatment of diseases associated with amyloid or amyloid-like proteins, like e.g. alzheimers
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US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
KR101600095B1 (ko) 2007-06-12 2016-03-07 에이씨 이뮨 에스.에이. 모노클로널 항 베타 아밀로이드 항체
US8613923B2 (en) 2007-06-12 2013-12-24 Ac Immune S.A. Monoclonal antibody
CA2700000A1 (en) * 2007-07-30 2009-02-05 Rick L. Tarleton Diagnostic assay for trypanosoma cruzi infection
CA2701790A1 (en) 2007-10-05 2009-04-16 Ac Immune S.A. Use of humanized anti-beta-amyloid antibody in ocular diseases
US9403902B2 (en) 2007-10-05 2016-08-02 Ac Immune S.A. Methods of treating ocular disease associated with amyloid-beta-related pathology using an anti-amyloid-beta antibody
JP5611834B2 (ja) 2007-12-27 2014-10-22 アボット・ラボラトリーズAbbott Laboratories 抗T.cruzi抗体及び使用方法
WO2009158729A2 (en) * 2008-06-27 2009-12-30 The Infectious Disease Research Institute Inc. Compounds and methods for diagnosis and treatment of chagas disease
ES2628743T3 (es) 2008-07-03 2017-08-03 Infectious Disease Research Institute Proteínas de fusión y su uso en el diagnóstico y tratamiento de la leishmaniasis
EP2311823A1 (en) 2009-10-15 2011-04-20 AC Immune S.A. 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases
DK2558446T5 (da) 2010-04-16 2019-12-09 Ac Immune Sa Nye forbindelser til behandling af sygdomme associerede med amyloid- eller amyloidlignende proteiner
US20110256064A1 (en) 2010-04-16 2011-10-20 Ac Immune, S.A. Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins
JP6081356B2 (ja) 2010-07-30 2017-02-15 エーシー イミューン エス.エー. 安全で機能的なヒト化抗βアミロイド抗体
MY164376A (en) 2010-10-07 2017-12-15 Univ Leuven Kath Phosphospecific antibodies recognizing tau
WO2012055933A1 (en) 2010-10-26 2012-05-03 Ac Immune S.A. Liposome-based construct comprising a peptide modified through hydrophobic moieties
AR092779A1 (es) 2011-10-07 2015-05-06 Ac Immune Sa Composicon farmaceutica que comprende anticuerpos que se unen a conformeros de proteinas tau
CA2869438C (en) 2012-04-05 2021-08-17 Ac Immune S.A. Humanized tau antibody
EP3505534A1 (en) 2012-06-08 2019-07-03 Sutro Biopharma, Inc. Antibodies comprising sitespecific nonnatural amino acid residues, methods of their preparation and methods of their use
ES2611788T3 (es) 2012-06-26 2017-05-10 Sutro Biopharma, Inc. Proteínas de Fc modificadas que comprenden residuos de aminoácidos no naturales específicos del sitio, conjugados de las mismas, métodos para su preparación y métodos para su uso
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Also Published As

Publication number Publication date
AU5362696A (en) 1996-10-08
DE69622385T2 (de) 2003-03-06
WO1996029605A3 (en) 1996-11-21
BR9607531A (pt) 1998-01-06
WO1996029605A2 (en) 1996-09-26
EP0815450B1 (en) 2002-07-17
US5942403A (en) 1999-08-24
ATE220797T1 (de) 2002-08-15
AR002282A1 (es) 1998-03-11
PT815450E (pt) 2002-12-31
CA2215104A1 (en) 1996-09-26
JPH11502923A (ja) 1999-03-09
EP0815450A2 (en) 1998-01-07
MX9707020A (es) 1998-06-30
US5756662A (en) 1998-05-26
DK0815450T3 (da) 2002-10-28
DE69622385D1 (de) 2002-08-22

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