BR9808251B1 - vacina, e, uso de uma proteìna isolada ou recombinante ou fragmento antigênico da mesma. - Google Patents
vacina, e, uso de uma proteìna isolada ou recombinante ou fragmento antigênico da mesma.Info
- Publication number
- BR9808251B1 BR9808251B1 BRPI9808251-5A BR9808251A BR9808251B1 BR 9808251 B1 BR9808251 B1 BR 9808251B1 BR 9808251 A BR9808251 A BR 9808251A BR 9808251 B1 BR9808251 B1 BR 9808251B1
- Authority
- BR
- Brazil
- Prior art keywords
- vaccine
- isolated
- recombinant protein
- antigenic fragment
- antibodies
- Prior art date
Links
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 title 1
- 239000012634 fragment Substances 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 241000242711 Fasciola hepatica Species 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000000366 juvenile effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
- C12N9/641—Cysteine endopeptidases (3.4.22)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43526—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms
- G01N2333/43547—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms from trematodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Environmental Sciences (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Virology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97200730 | 1997-03-11 | ||
PCT/NL1998/000146 WO1998040497A2 (en) | 1997-03-11 | 1998-03-11 | An ex vivo animal or challenge model as method to measure protective immunity directed against parasites and vaccines shown to be protective in said method |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9808251A BR9808251A (pt) | 2000-05-16 |
BR9808251B1 true BR9808251B1 (pt) | 2012-09-04 |
Family
ID=8228093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9808251-5A BR9808251B1 (pt) | 1997-03-11 | 1998-03-11 | vacina, e, uso de uma proteìna isolada ou recombinante ou fragmento antigênico da mesma. |
Country Status (11)
Country | Link |
---|---|
US (5) | US6551594B1 (pt) |
EP (1) | EP0966537B1 (pt) |
JP (1) | JP4321881B2 (pt) |
AT (1) | ATE420184T1 (pt) |
AU (1) | AU6424298A (pt) |
BR (1) | BR9808251B1 (pt) |
CA (1) | CA2284110C (pt) |
DE (1) | DE69840433D1 (pt) |
NZ (1) | NZ337697A (pt) |
TR (1) | TR199902609T2 (pt) |
WO (1) | WO1998040497A2 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69840433D1 (de) | 1997-03-11 | 2009-02-26 | Stichting Dienst Landbouwkundi | Fasciola hepatica impfstoffe |
ES2184569B1 (es) * | 2000-08-07 | 2004-02-01 | Inst Nac Investigacion Inia | Empleo de los productos de excrecion secrecion de fasciola hepatica en la elaboracion de un medicamento para el tratamiento de enfermedades hepaticas y/o para evitar o reducir el rechazo al transplante hepatico. |
US20040091914A1 (en) * | 2002-08-02 | 2004-05-13 | Sysmex Corporation | Gene assay method for predicting glaucoma onset risk |
AU2006322887A1 (en) * | 2005-12-05 | 2007-06-14 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Compositions and methods for modulating an immune response |
AU2016233223A1 (en) | 2015-03-18 | 2017-09-14 | The United States Government, As Represented By The Secretary Of The Department Of Health And Human Services | Immunogenic compositions and vaccines for preventing or treating filarial disease |
GB201714057D0 (en) * | 2017-09-01 | 2017-10-18 | Univ College Dublin Nat Univ Of Ireland Dublin | A fasciola hepatica antigen and vaccine |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8432401D0 (en) * | 1984-12-21 | 1985-02-06 | Bennett C E | Liver fluke antigens |
PT666919E (pt) * | 1992-10-21 | 2003-09-30 | John Pius Dalton | Vacina contendo uma protease de tiol |
JPH07505787A (ja) * | 1993-02-05 | 1995-06-29 | ダラテク・プロプライエタリー・リミテッド | ファスキオラ種から取得可能なポリペプチド類,およびワクチン,処置法およびそのdna配列 |
US5756662A (en) | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
DE69840433D1 (de) | 1997-03-11 | 2009-02-26 | Stichting Dienst Landbouwkundi | Fasciola hepatica impfstoffe |
-
1998
- 1998-03-11 DE DE69840433T patent/DE69840433D1/de not_active Expired - Fee Related
- 1998-03-11 AT AT98909874T patent/ATE420184T1/de not_active IP Right Cessation
- 1998-03-11 EP EP98909874A patent/EP0966537B1/en not_active Expired - Lifetime
- 1998-03-11 US US09/381,122 patent/US6551594B1/en not_active Expired - Lifetime
- 1998-03-11 WO PCT/NL1998/000146 patent/WO1998040497A2/en active Application Filing
- 1998-03-11 BR BRPI9808251-5A patent/BR9808251B1/pt not_active IP Right Cessation
- 1998-03-11 JP JP53947498A patent/JP4321881B2/ja not_active Expired - Lifetime
- 1998-03-11 NZ NZ337697A patent/NZ337697A/en not_active IP Right Cessation
- 1998-03-11 CA CA2284110A patent/CA2284110C/en not_active Expired - Lifetime
- 1998-03-11 AU AU64242/98A patent/AU6424298A/en not_active Abandoned
- 1998-03-11 TR TR1999/02609T patent/TR199902609T2/xx unknown
-
2003
- 2003-03-06 US US10/382,479 patent/US20030224007A1/en not_active Abandoned
-
2007
- 2007-07-26 US US11/881,598 patent/US7744907B2/en not_active Expired - Fee Related
-
2010
- 2010-05-10 US US12/800,205 patent/US8088909B2/en not_active Expired - Fee Related
-
2011
- 2011-11-14 US US13/373,428 patent/US8507658B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
TR199902609T2 (xx) | 2000-06-21 |
US20100285049A1 (en) | 2010-11-11 |
CA2284110C (en) | 2012-08-28 |
US6551594B1 (en) | 2003-04-22 |
WO1998040497A3 (en) | 1998-12-10 |
ATE420184T1 (de) | 2009-01-15 |
US7744907B2 (en) | 2010-06-29 |
WO1998040497A2 (en) | 1998-09-17 |
US20030224007A1 (en) | 2003-12-04 |
US20080138358A1 (en) | 2008-06-12 |
NZ337697A (en) | 2001-06-29 |
US20120107342A1 (en) | 2012-05-03 |
BR9808251A (pt) | 2000-05-16 |
EP0966537B1 (en) | 2009-01-07 |
CA2284110A1 (en) | 1998-09-17 |
US8088909B2 (en) | 2012-01-03 |
EP0966537A2 (en) | 1999-12-29 |
DE69840433D1 (de) | 2009-02-26 |
AU6424298A (en) | 1998-09-29 |
US8507658B2 (en) | 2013-08-13 |
JP2001527391A (ja) | 2001-12-25 |
JP4321881B2 (ja) | 2009-08-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25G | Requested change of headquarter approved |
Owner name: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020070000611/RJ DE 02/01/2007. |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/09/2012, OBSERVADAS AS CONDICOES LEGAIS. |
|
B25D | Requested change of name of applicant approved | ||
B25G | Requested change of headquarter approved | ||
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 21A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2505 DE 08-01-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |