BR9813637A - Compostos e métodos para a detecção e prevençãode infecção por t. cruzi - Google Patents
Compostos e métodos para a detecção e prevençãode infecção por t. cruziInfo
- Publication number
- BR9813637A BR9813637A BR9813637-2A BR9813637A BR9813637A BR 9813637 A BR9813637 A BR 9813637A BR 9813637 A BR9813637 A BR 9813637A BR 9813637 A BR9813637 A BR 9813637A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- infection
- cruzi
- prevention
- detection
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 208000015181 infectious disease Diseases 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 241000223109 Trypanosoma cruzi Species 0.000 abstract 5
- 206010001935 American trypanosomiasis Diseases 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 208000024699 Chagas disease Diseases 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"COMPOSTOS E MéTODOS PARA A DETECçãO EPREVENçãO DE INFECçãO POR T. CRUZI". Compostos eprocessos são providos para diagnóstico de infecção comTrypanosoma cruzi. Os compostos mostrados são polipeptídios, ouanticorpos para os mesmos, que contêm um ou mais epítopos deantígenos de T. cruzi. Os compostos são úteis em uma variedadede ensaios imuno para detecção de infecção de T. cruzi. Oscompostos polipeptídios ainda são úteis em vacinas ecomposições farmacêuticas para indução de imunidade protetoracontra doença de Chagas em indivíduos expostos a T. cruzi.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/993,674 US6228372B1 (en) | 1997-04-15 | 1997-12-18 | Compounds and methods for the detection and prevention of T. cruzi infection |
PCT/US1998/025871 WO1999031246A1 (en) | 1997-12-18 | 1998-12-04 | Compounds and methods for the detection and prevention of t. cruzi infection |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9813637A true BR9813637A (pt) | 2001-12-04 |
Family
ID=25539818
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9813637-2A BR9813637A (pt) | 1997-12-18 | 1998-12-04 | Compostos e métodos para a detecção e prevençãode infecção por t. cruzi |
Country Status (8)
Country | Link |
---|---|
US (1) | US6228372B1 (pt) |
EP (1) | EP1038000A1 (pt) |
JP (1) | JP2002508506A (pt) |
AR (1) | AR014132A1 (pt) |
AU (1) | AU1805799A (pt) |
BR (1) | BR9813637A (pt) |
CO (1) | CO4820439A1 (pt) |
WO (1) | WO1999031246A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6375955B1 (en) * | 1995-09-22 | 2002-04-23 | Corixa Corporation | Leishmania antigens for use in the therapy and diagnosis of leishmaniasis |
US6228372B1 (en) | 1997-04-15 | 2001-05-08 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
US6419933B1 (en) | 1995-11-14 | 2002-07-16 | Corixa Corporation | Compounds and methods for the detection and prevention of T.cruzi infection |
EP1945248A4 (en) * | 2005-11-03 | 2008-12-31 | Inbios Internat Inc | COMPOSITIONS AND METHODS FOR DETECTING A TRYPANOSOMA CRUZI INFECTION |
US7749717B2 (en) * | 2006-10-19 | 2010-07-06 | Abbott Laboratories | Methods for the detection and diagnosis of Trypanosoma cruzi infection |
CA3023887A1 (en) * | 2007-12-27 | 2009-07-09 | Abbott Laboratories | Anti-t. cruzi antibodies and methods of use |
US8231881B2 (en) | 2008-07-03 | 2012-07-31 | Infectious Disease Research Institute | Fusion proteins and their use in the diagnosis and treatment of leishmaniasis |
EP3215849B1 (en) * | 2014-11-06 | 2018-12-19 | Roche Diagnostics GmbH | Recombinant trypanosoma cruzi jl7 antigen variants and their use for detecting chagas disease |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4870006A (en) | 1986-07-24 | 1989-09-26 | Codon | Antigenic material for a chagas' disease detection system |
WO1990002564A1 (en) | 1988-09-12 | 1990-03-22 | Codon | Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi |
BR9006039A (pt) | 1990-11-28 | 1992-07-14 | Fundacao Oswaldo Cruz | Processo para preparacao de antigeno conjugado a atividade enzimatica,composicao a base de conjugado enzima-antigeno para utilizacao em diagnostico imunologico e kits de diagnostico imunologico da doenca de chagas a base da dita composicao,para aplicacao individual e/ou em inqueritos epidemiologicos |
US5304371A (en) | 1992-02-14 | 1994-04-19 | Lasys Corporation | Peptide for diagnosing and immunizing against T. cruzi infection |
TW246717B (pt) | 1992-07-10 | 1995-05-01 | Abbott Lab | |
US5756662A (en) | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
US6228372B1 (en) | 1997-04-15 | 2001-05-08 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
US5916572A (en) | 1995-11-14 | 1999-06-29 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
-
1997
- 1997-12-18 US US08/993,674 patent/US6228372B1/en not_active Expired - Lifetime
-
1998
- 1998-12-04 JP JP2000539145A patent/JP2002508506A/ja active Pending
- 1998-12-04 WO PCT/US1998/025871 patent/WO1999031246A1/en not_active Application Discontinuation
- 1998-12-04 AU AU18057/99A patent/AU1805799A/en not_active Abandoned
- 1998-12-04 BR BR9813637-2A patent/BR9813637A/pt not_active IP Right Cessation
- 1998-12-04 EP EP98962923A patent/EP1038000A1/en not_active Withdrawn
- 1998-12-17 AR ARP980106437A patent/AR014132A1/es not_active Application Discontinuation
- 1998-12-18 CO CO98075441A patent/CO4820439A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO1999031246A1 (en) | 1999-06-24 |
CO4820439A1 (es) | 1999-07-28 |
AU1805799A (en) | 1999-07-05 |
US6228372B1 (en) | 2001-05-08 |
EP1038000A1 (en) | 2000-09-27 |
JP2002508506A (ja) | 2002-03-19 |
AR014132A1 (es) | 2001-02-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A,7A E 8A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007. |