CO4820439A1 - Compuestos y metodos para la deteccion y la prevencion de la infeccion por el t. cruzi - Google Patents
Compuestos y metodos para la deteccion y la prevencion de la infeccion por el t. cruziInfo
- Publication number
- CO4820439A1 CO4820439A1 CO98075441A CO98075441A CO4820439A1 CO 4820439 A1 CO4820439 A1 CO 4820439A1 CO 98075441 A CO98075441 A CO 98075441A CO 98075441 A CO98075441 A CO 98075441A CO 4820439 A1 CO4820439 A1 CO 4820439A1
- Authority
- CO
- Colombia
- Prior art keywords
- compounds
- detection
- methods
- cruzi
- cruzi infection
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 238000001514 detection method Methods 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 206010001935 American trypanosomiasis Diseases 0.000 abstract 2
- 208000024699 Chagas disease Diseases 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 241000223109 Trypanosoma cruzi Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se proveen compuestos y métodos para el diagnóstico de lainfección por el Trypanosoma cruzi. Los compuestos presentados son polipéptidos o anticuerpos de los mismos, que contienen uno o más epitopos de los antígenos del T. Cruzi. Los compuestos resultan de utilidad en una variedad de inmunoensayos para la detección de la infección por T. Cruzi. Los compuestos de polipéptidos también resultan útiles en las vacunas y en las composiciones farmacéuticas para inducir una inmunidad protectora contra el mal de Chagas en individuos expuestos al T. Cruzi.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/993,674 US6228372B1 (en) | 1997-04-15 | 1997-12-18 | Compounds and methods for the detection and prevention of T. cruzi infection |
Publications (1)
Publication Number | Publication Date |
---|---|
CO4820439A1 true CO4820439A1 (es) | 1999-07-28 |
Family
ID=25539818
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO98075441A CO4820439A1 (es) | 1997-12-18 | 1998-12-18 | Compuestos y metodos para la deteccion y la prevencion de la infeccion por el t. cruzi |
Country Status (8)
Country | Link |
---|---|
US (1) | US6228372B1 (es) |
EP (1) | EP1038000A1 (es) |
JP (1) | JP2002508506A (es) |
AR (1) | AR014132A1 (es) |
AU (1) | AU1805799A (es) |
BR (1) | BR9813637A (es) |
CO (1) | CO4820439A1 (es) |
WO (1) | WO1999031246A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6375955B1 (en) * | 1995-09-22 | 2002-04-23 | Corixa Corporation | Leishmania antigens for use in the therapy and diagnosis of leishmaniasis |
US6419933B1 (en) * | 1995-11-14 | 2002-07-16 | Corixa Corporation | Compounds and methods for the detection and prevention of T.cruzi infection |
US6228372B1 (en) | 1997-04-15 | 2001-05-08 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
EP1945248A4 (en) * | 2005-11-03 | 2008-12-31 | Inbios Internat Inc | COMPOSITIONS AND METHODS FOR DETECTING A TRYPANOSOMA CRUZI INFECTION |
US7749717B2 (en) * | 2006-10-19 | 2010-07-06 | Abbott Laboratories | Methods for the detection and diagnosis of Trypanosoma cruzi infection |
CA2710761C (en) * | 2007-12-27 | 2019-01-08 | Abbott Laboratories | Anti-t. cruzi antibodies and methods of use |
BRPI0913972B1 (pt) | 2008-07-03 | 2018-06-26 | Infectious Disease Research Institute | Polipeptídeo de fusão compreendendo antígenos de leishmania, polinucleotídeo, composição farmacêutica, bem como métodos para detecção de infecção e para identificação de leishmaniose e kit diagnóstico para detecção e identificação de leishmaniose |
MX2017005644A (es) * | 2014-11-06 | 2017-06-29 | Hoffmann La Roche | Variantes de antigeno trypanosoma cruzi jl7 recombinante y su uso para detectar la enfermedad de chagas. |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4870006A (en) | 1986-07-24 | 1989-09-26 | Codon | Antigenic material for a chagas' disease detection system |
WO1990002564A1 (en) | 1988-09-12 | 1990-03-22 | Codon | Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi |
BR9006039A (pt) | 1990-11-28 | 1992-07-14 | Fundacao Oswaldo Cruz | Processo para preparacao de antigeno conjugado a atividade enzimatica,composicao a base de conjugado enzima-antigeno para utilizacao em diagnostico imunologico e kits de diagnostico imunologico da doenca de chagas a base da dita composicao,para aplicacao individual e/ou em inqueritos epidemiologicos |
US5304371A (en) | 1992-02-14 | 1994-04-19 | Lasys Corporation | Peptide for diagnosing and immunizing against T. cruzi infection |
TW246717B (es) | 1992-07-10 | 1995-05-01 | Abbott Lab | |
US5756662A (en) | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
US6228372B1 (en) | 1997-04-15 | 2001-05-08 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
US5916572A (en) | 1995-11-14 | 1999-06-29 | Corixa Corporation | Compounds and methods for the detection and prevention of T. cruzi infection |
-
1997
- 1997-12-18 US US08/993,674 patent/US6228372B1/en not_active Expired - Lifetime
-
1998
- 1998-12-04 JP JP2000539145A patent/JP2002508506A/ja active Pending
- 1998-12-04 BR BR9813637-2A patent/BR9813637A/pt not_active IP Right Cessation
- 1998-12-04 AU AU18057/99A patent/AU1805799A/en not_active Abandoned
- 1998-12-04 WO PCT/US1998/025871 patent/WO1999031246A1/en not_active Application Discontinuation
- 1998-12-04 EP EP98962923A patent/EP1038000A1/en not_active Withdrawn
- 1998-12-17 AR ARP980106437A patent/AR014132A1/es not_active Application Discontinuation
- 1998-12-18 CO CO98075441A patent/CO4820439A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO1999031246A1 (en) | 1999-06-24 |
AU1805799A (en) | 1999-07-05 |
JP2002508506A (ja) | 2002-03-19 |
BR9813637A (pt) | 2001-12-04 |
AR014132A1 (es) | 2001-02-07 |
EP1038000A1 (en) | 2000-09-27 |
US6228372B1 (en) | 2001-05-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2180754T3 (es) | Compuestos y metodos para la deteccion de infeccion por t. cruzi. | |
DK0528859T3 (da) | Oral vaccine, som omfatter antigen knyttet til overfladen af røde blodlegemer | |
YU48250B (sh) | Postupak za pripremanje aktivne vakcine protiv lajmske bolesti | |
Mitsuyasu et al. | Heterogeneity of epidemic Kaposi's sarcoma. Implications for therapy | |
BG95337A (bg) | Ваксиниране и методи срещу заболявания,резултат от патогенни отговори на т-клетъчно специфични популации | |
SE8604007D0 (sv) | Vaccin och immunoanalyser for forvervat immunbristsyndrom (aids) | |
PT714444E (pt) | Atenuacao de um epitopo imunodominante de um antigenio para utilizacao em vacinas e imunoterapias para plantas, animais e homens | |
AR020102A1 (es) | Compuesto para la prevencion y/o tratamiento de la alergia; composicion farmaceutica, composicion cosmetica, composicion en forma de bebida, alimento y/oalimento para animales domesticos que lo comprende y uso de dicho compuesto o dicha composicion farmaceutica para la fabricacion de un alimento | |
CY1111193T1 (el) | Ανθρωπινα cdr-μοσχευμενα αντισωματα και θραυσματα αντισωματων τους | |
NO991524L (no) | Vaksiner | |
AR073452A1 (es) | Proteinas de fusion que comprende dos o mas antigenos de leishmania y su uso en el diagnostico y tratamiento de leishmaniasis | |
CO4820439A1 (es) | Compuestos y metodos para la deteccion y la prevencion de la infeccion por el t. cruzi | |
ATE375514T1 (de) | Zusammensetzungen und methoden zur detektion einer trypanosoma cruzi infektion | |
ES2168520T3 (es) | Compuestos y metodo para la deteccion y prevencion de infeccion por t. cruzi. | |
NO923778D0 (no) | Multippel sklerose t-celle-reseptor | |
ES2061705T3 (es) | Procedimiento de obtencion de un preparado antigenico de toxoplasma gondii y sus aplicaciones diagnosticas y profilacticas. | |
BR0109164A (pt) | Anticorpos monoclonais para o receptor humano para ldl, produção e uso dos mesmos | |
ES2118720T3 (es) | Produccion y utilizacion de agentes antihelminticos e inmunogenos protectores. | |
BR0009077A (pt) | Antìgenos de tuberculose e métodos de uso dos mesmos | |
DE69525058D1 (de) | Präsentation von aus lipoarabinomannan bestehenden antigenen an t-zellen durch cd1 moleküle | |
ES2057579T3 (es) | Peptidos e1 y c de rubeola. | |
Sanchez et al. | Immunological response to Vibrio cholerae O1 infection and an oral cholera vaccine among Peruvians | |
ES2090331T3 (es) | Ctaa 28a32, antigeno reconocido por mca 28a32. | |
AR020852A1 (es) | Antigenos de vacuna de leptospira para la prevencion de leptospirosis | |
AR027738A1 (es) | Composicion coadyuvante, composiciones de vacunas que incluyen dicha composicion coadyuvante; procedimiento de induccion de inmunorespuestas antigenicas enmamiferos y procedimiento de tratamiento donde se aplican dichas vacunas |