MX9302024A - Epitopes de celula t de los alergenos principales de ambrosina artemisfolia. - Google Patents
Epitopes de celula t de los alergenos principales de ambrosina artemisfolia.Info
- Publication number
- MX9302024A MX9302024A MX9302024A MX9302024A MX9302024A MX 9302024 A MX9302024 A MX 9302024A MX 9302024 A MX9302024 A MX 9302024A MX 9302024 A MX9302024 A MX 9302024A MX 9302024 A MX9302024 A MX 9302024A
- Authority
- MX
- Mexico
- Prior art keywords
- amb
- allergens
- artemisfolia
- ambrosine
- cell epitopes
- Prior art date
Links
- 239000013566 allergen Substances 0.000 title abstract 5
- TUKMYOLTOOBHQF-XGUBFFRZSA-N ambrosine Natural products C1[C@H](C(C)C)CC[C@H](C)[C@@H]2CCC[C@]21C TUKMYOLTOOBHQF-XGUBFFRZSA-N 0.000 title 1
- 244000036975 Ambrosia artemisiifolia Species 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 235000003133 Ambrosia artemisiifolia Nutrition 0.000 abstract 1
- 235000003129 Ambrosia artemisiifolia var elatior Nutrition 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 108091005601 modified peptides Proteins 0.000 abstract 1
- 239000009342 ragweed pollen Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención proporciona péptidos aislados de los principales alergenos proteicos de Ambrosia artemisiifolia, o polen de ambrosía corta. Los péptidos dentro del alcance de esta invención comprende por lo menos un epitopo para células, o preferiblemente por lo menos dos epitopos para la célula T de un alergeno proteico seleccionado de los alergenos Amb a I.1, Amb a I.2, Amb a I.3, Amb a I.4 y Amb a II. Se describen péptidos modificados que tienen propiedades terapéuticas similares o mejoradas en comparación con el alergeno o porción del mismo correspondiente, que se presenta de manera natural, pero que tienen efectos laterales reducidos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86667992A | 1992-04-09 | 1992-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9302024A true MX9302024A (es) | 1994-07-29 |
Family
ID=25348157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9302024A MX9302024A (es) | 1992-04-09 | 1993-04-07 | Epitopes de celula t de los alergenos principales de ambrosina artemisfolia. |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP0636180A1 (es) |
| JP (1) | JPH07507924A (es) |
| KR (1) | KR950700991A (es) |
| AU (1) | AU685392B2 (es) |
| CA (1) | CA2117779A1 (es) |
| FI (1) | FI944697A (es) |
| IL (1) | IL105352A0 (es) |
| MX (1) | MX9302024A (es) |
| NO (1) | NO943811L (es) |
| NZ (1) | NZ252013A (es) |
| WO (1) | WO1993021321A2 (es) |
| ZA (1) | ZA932530B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6759234B1 (en) | 1994-09-02 | 2004-07-06 | Immulogic Pharmaceutical Corporation | Compositions and methods for administering to humans, peptides capable of down regulating an antigen specific immune response |
| AU748104B2 (en) * | 1994-09-02 | 2002-05-30 | Merck Patent Gmbh | Peptide compositions capable of down regulating an antigen specific immune response |
| NZ273815A (en) * | 1994-09-02 | 1999-05-28 | Immulogic Pharma Corp | Peptide compositions for treating protein allergies or autoimmune diseases containing at least two isolated and purified peptides |
| AU4146796A (en) * | 1994-10-27 | 1996-05-23 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from ambrosia artemisiifolia |
| ATE296444T1 (de) | 1996-03-21 | 2005-06-15 | Circassia Ltd | Kryptische peptide und verfahren zu ihrer identifizierung |
| WO2001077353A2 (en) * | 2000-04-05 | 2001-10-18 | Syngenta Participations Ag | Expression of pollen allergens in plastids |
| EP1958645A1 (en) * | 2007-02-13 | 2008-08-20 | Biomay AG | Peptides derived from the major allergen of ragweed (Ambrosia artemisiifolia) and uses thereof |
| GB0710529D0 (en) | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| ES2378870T5 (es) | 2008-08-15 | 2016-02-03 | Circassia Limited | Vacuna que comprende péptidos Amb a 1 para uso en el tratamiento de alergia a ambrosía |
| WO2010018384A1 (en) | 2008-08-15 | 2010-02-18 | Circassia Limited | T-cell antigen peptide from allergen for stimulation of il-10 production |
| GB0821806D0 (en) | 2008-11-28 | 2009-01-07 | Circassia Ltd | Compositions with reduced dimer formation |
| DK2723373T3 (en) * | 2011-06-27 | 2017-09-18 | Anergis S A | OVERLAPPING ADJUSTING PEPTIDES FOR TREATMENT |
| WO2017179025A1 (en) * | 2016-04-15 | 2017-10-19 | Alk-Abelló A/S | Epitope polypeptides of ragweed pollen allergens |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2049921C (en) * | 1989-03-17 | 2004-06-15 | Bruce Rogers | Allergenic proteins from ragweed and uses therefor |
-
1993
- 1993-04-06 EP EP93911584A patent/EP0636180A1/en not_active Withdrawn
- 1993-04-06 WO PCT/US1993/003156 patent/WO1993021321A2/en not_active Application Discontinuation
- 1993-04-06 CA CA002117779A patent/CA2117779A1/en not_active Abandoned
- 1993-04-06 NZ NZ252013A patent/NZ252013A/en unknown
- 1993-04-06 AU AU40462/93A patent/AU685392B2/en not_active Expired - Fee Related
- 1993-04-06 EP EP96202492A patent/EP0770681A3/en not_active Withdrawn
- 1993-04-06 JP JP5518403A patent/JPH07507924A/ja active Pending
- 1993-04-07 MX MX9302024A patent/MX9302024A/es unknown
- 1993-04-08 ZA ZA932530A patent/ZA932530B/xx unknown
- 1993-04-09 IL IL105352A patent/IL105352A0/xx unknown
-
1994
- 1994-10-07 FI FI944697A patent/FI944697A/fi not_active Application Discontinuation
- 1994-10-07 NO NO943811A patent/NO943811L/no unknown
- 1994-10-08 KR KR1019940703588A patent/KR950700991A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0770681A2 (en) | 1997-05-02 |
| JPH07507924A (ja) | 1995-09-07 |
| KR950700991A (ko) | 1995-02-20 |
| NZ252013A (en) | 1996-08-27 |
| FI944697A0 (fi) | 1994-10-07 |
| WO1993021321A2 (en) | 1993-10-28 |
| NO943811L (no) | 1994-12-06 |
| EP0770681A3 (en) | 1997-06-04 |
| AU685392B2 (en) | 1998-01-22 |
| CA2117779A1 (en) | 1993-10-28 |
| WO1993021321A3 (en) | 1994-02-03 |
| EP0636180A1 (en) | 1995-02-01 |
| FI944697A (fi) | 1994-12-07 |
| AU4046293A (en) | 1993-11-18 |
| IL105352A0 (en) | 1993-08-18 |
| NO943811D0 (no) | 1994-10-07 |
| ZA932530B (en) | 1993-10-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9302024A (es) | Epitopes de celula t de los alergenos principales de ambrosina artemisfolia. | |
| ATE415173T1 (de) | Pan dr-bindeproteinen zur erhöhung der immunantwort | |
| FI941757A0 (fi) | Dermatofagoideista (talopölypunkki) peräisin olevien pääallergeenien T-soluepitoopit | |
| BR9408063A (pt) | Antagonistas de receptores de taquicinina que nÆo sÆo pept¡deos | |
| NO983999L (no) | Peptidimmunogener for vaksinasjon mot og behandling av allergi | |
| DK1090039T3 (da) | Peptidsammensætning som immunogen til behandling af allergi | |
| DE69432984D1 (de) | Therapeutische substituierte guanidine | |
| BR0205983A (pt) | fármacos peptìdicos antiangiogênicos | |
| IL147766A0 (en) | Therapeutic compounds comprised of anti-fc receptor binding agents | |
| DK0610335T3 (da) | Fremgangsmåder til udformning af rekombitope peptider | |
| George et al. | Oxidized low‐density lipoprotein (Ox‐LDL) but not LDL aggravates the manifestations of experimental antiphospholipid syndrome (APS) | |
| PT845998E (pt) | Medicamentos para imunoterapia contendo anticorpos que reconhecem de forma especifica o antigenio mhcii de um paciente a ser tratado | |
| MX9301675A (es) | Composiciones que contienen peptidos para inducir tolerancia de las celulas t a un antigeno. | |
| ATE326981T1 (de) | Isolierte peptide die aminosäuresequenzen von ny- eso-1 entsprechen und an mhc-klasse i und mhc klasse ii moleküle binden, und deren verwendungen | |
| DK1025849T5 (da) | Fremgangsmåder til påvisning og behandling af individer, som har unormale celler, som udtrykker HLC-A2/tyrosinasepeptid-antigener | |
| MX9304621A (es) | Tensioactivos pulmonares de peptidos sinteticos que tienen antioxidantes unidos covalentemente. | |
| NO950526L (no) | T-celleepitoper av raigresspollen-allergen | |
| ATE406178T1 (de) | Verhinderung von immunreaktivität durch verarmung oder inhibition von antigen-präsentierenden zellen | |
| SE9703531D0 (sv) | Non-anaphlactic forms of allergens and their use | |
| ES2085947T3 (es) | Proteinas hibridas protectoras de plasmodium falciparum que contienen secuencias parciales de los antigenos de malaria hrpii y serp. | |
| CA2160121A1 (en) | T cell epitopes of the major allergens from dermatophagoides (house dust mite) | |
| Kojima et al. | Inhibition of complement‐mediated immune hemolysis by the constant domain of immunoglobulin | |
| ES2183376T3 (es) | Uso de lbp para el tratamiento de la septicemia. |