MX9205491A - Sintesis regioselectiva de agentes anti-inflamatorios de 1,5-diaril pirazol - Google Patents
Sintesis regioselectiva de agentes anti-inflamatorios de 1,5-diaril pirazolInfo
- Publication number
- MX9205491A MX9205491A MX9205491A MX9205491A MX9205491A MX 9205491 A MX9205491 A MX 9205491A MX 9205491 A MX9205491 A MX 9205491A MX 9205491 A MX9205491 A MX 9205491A MX 9205491 A MX9205491 A MX 9205491A
- Authority
- MX
- Mexico
- Prior art keywords
- diaril
- pirazol
- inflammatory agents
- regioselective synthesis
- regioselective
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/766,611 US5117054A (en) | 1991-09-26 | 1991-09-26 | N-hydroxy, N-methyl propanamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9205491A true MX9205491A (es) | 1993-05-01 |
Family
ID=25076968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9205491A MX9205491A (es) | 1991-09-26 | 1992-09-25 | Sintesis regioselectiva de agentes anti-inflamatorios de 1,5-diaril pirazol |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5117054A (es) |
| EP (1) | EP0534800A3 (es) |
| JP (1) | JPH05320137A (es) |
| KR (1) | KR930005982A (es) |
| CN (1) | CN1071161A (es) |
| AR (1) | AR248396A1 (es) |
| AU (1) | AU2358592A (es) |
| CA (1) | CA2079045A1 (es) |
| FI (1) | FI924307A (es) |
| HU (1) | HUT62862A (es) |
| IL (1) | IL103173A0 (es) |
| MX (1) | MX9205491A (es) |
| NO (1) | NO923728L (es) |
| TW (1) | TW215085B (es) |
| ZA (1) | ZA927393B (es) |
| ZW (1) | ZW15092A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5117054A (en) * | 1991-09-26 | 1992-05-26 | Ortho Pharmaceutical Corporation | N-hydroxy, N-methyl propanamides |
| FR2692575B1 (fr) * | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| DE19723631A1 (de) * | 1997-06-05 | 1998-12-10 | Consortium Elektrochem Ind | Mehrkomponentensystem zum Verändern, Abbau oder Bleichen von Lignin, ligninhaltigen Materialien oder ähnlichen Stoffen sowie Verfahren zu seiner Anwendung |
| PT1413575E (pt) * | 1999-08-03 | 2006-12-29 | Ortho Mcneil Pharm Inc | Processo para a preparação derivados de ácido (1, 5-diaril) pirazol-3-il]propanóico |
| JP2006522164A (ja) * | 2003-04-03 | 2006-09-28 | メルク エンド カムパニー インコーポレーテッド | 代謝調節型グルタミン酸受容体−５のジアリール置換ピラゾール修飾因子 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4218478A (en) * | 1979-01-05 | 1980-08-19 | Ruiko Oiwa | Trichostatin as an antiprotozoal agent |
| US4826868A (en) * | 1986-05-29 | 1989-05-02 | Ortho Pharmaceutical Corporation | 1,5-Diaryl-3-substituted pyrazoles pharmaceutical compositions and use |
| US4681894A (en) * | 1986-09-26 | 1987-07-21 | Ortho Pharmaceutical Corporation | Hydroxamic acids and esters |
| US4861798A (en) * | 1986-12-29 | 1989-08-29 | Bristol-Myers Company | Lipoxygenase inhibitory compounds |
| US4898952A (en) * | 1987-05-29 | 1990-02-06 | Ortho Pharmaceutical Corporation | Regioselective synthesis of a 1,5-disubstituted pyrazole |
| AU611437B2 (en) * | 1987-05-29 | 1991-06-13 | Ortho Pharmaceutical Corporation | Pharmacologically active 2- and 3-substituted (1',5'-diaryl-3-pyrazolyl)-n-hydroxypropanamides and method for synthesizing the same |
| GB9005028D0 (en) * | 1990-03-06 | 1990-05-02 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5117054A (en) * | 1991-09-26 | 1992-05-26 | Ortho Pharmaceutical Corporation | N-hydroxy, N-methyl propanamides |
-
1991
- 1991-09-26 US US07/766,611 patent/US5117054A/en not_active Expired - Lifetime
-
1992
- 1992-09-14 AU AU23585/92A patent/AU2358592A/en not_active Abandoned
- 1992-09-15 IL IL103173A patent/IL103173A0/xx unknown
- 1992-09-22 JP JP4276803A patent/JPH05320137A/ja active Pending
- 1992-09-24 CA CA002079045A patent/CA2079045A1/en not_active Abandoned
- 1992-09-24 KR KR1019920017427A patent/KR930005982A/ko not_active Application Discontinuation
- 1992-09-25 ZW ZW15092A patent/ZW15092A1/xx unknown
- 1992-09-25 HU HU9203078A patent/HUT62862A/hu unknown
- 1992-09-25 ZA ZA927393A patent/ZA927393B/xx unknown
- 1992-09-25 NO NO92923728A patent/NO923728L/no unknown
- 1992-09-25 AR AR92323281A patent/AR248396A1/es active
- 1992-09-25 FI FI924307A patent/FI924307A/fi not_active Application Discontinuation
- 1992-09-25 MX MX9205491A patent/MX9205491A/es unknown
- 1992-09-26 CN CN92111454A patent/CN1071161A/zh active Pending
- 1992-09-28 EP EP19920308811 patent/EP0534800A3/en not_active Withdrawn
- 1992-10-06 TW TW081107906A patent/TW215085B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| HUT62862A (en) | 1993-06-28 |
| HU9203078D0 (en) | 1992-12-28 |
| AR248396A1 (es) | 1995-08-18 |
| EP0534800A3 (en) | 1993-06-16 |
| NO923728D0 (no) | 1992-09-25 |
| CA2079045A1 (en) | 1993-03-27 |
| AU2358592A (en) | 1993-04-01 |
| IL103173A0 (en) | 1993-02-21 |
| CN1071161A (zh) | 1993-04-21 |
| TW215085B (es) | 1993-10-21 |
| US5117054A (en) | 1992-05-26 |
| KR930005982A (ko) | 1993-04-20 |
| JPH05320137A (ja) | 1993-12-03 |
| ZA927393B (en) | 1994-03-25 |
| FI924307A (fi) | 1993-03-27 |
| NO923728L (no) | 1993-03-29 |
| EP0534800A2 (en) | 1993-03-31 |
| FI924307A0 (fi) | 1992-09-25 |
| ZW15092A1 (en) | 1994-06-15 |
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