NO923728L - Regioselektiv syntese av inflammatorisk aktive 1,5-diarylpyrazoler - Google Patents

Regioselektiv syntese av inflammatorisk aktive 1,5-diarylpyrazoler

Info

Publication number
NO923728L
NO923728L NO92923728A NO923728A NO923728L NO 923728 L NO923728 L NO 923728L NO 92923728 A NO92923728 A NO 92923728A NO 923728 A NO923728 A NO 923728A NO 923728 L NO923728 L NO 923728L
Authority
NO
Norway
Prior art keywords
inflammatorally
active
regioselective synthesis
diaryl pyrazoles
pyrazoles
Prior art date
Application number
NO92923728A
Other languages
English (en)
Norwegian (no)
Other versions
NO923728D0 (no
Inventor
William V Murray
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of NO923728D0 publication Critical patent/NO923728D0/no
Publication of NO923728L publication Critical patent/NO923728L/no
Priority to NO931940A priority Critical patent/NO931940D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/76Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C235/78Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58One oxygen atom, e.g. butenolide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
NO92923728A 1991-09-26 1992-09-25 Regioselektiv syntese av inflammatorisk aktive 1,5-diarylpyrazoler NO923728L (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO931940A NO931940D0 (no) 1991-09-26 1993-05-27 Regioselektiv syntese av inflammatorisk aktive 1,5-diarylpyrazoler

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/766,611 US5117054A (en) 1991-09-26 1991-09-26 N-hydroxy, N-methyl propanamides

Publications (2)

Publication Number Publication Date
NO923728D0 NO923728D0 (no) 1992-09-25
NO923728L true NO923728L (no) 1993-03-29

Family

ID=25076968

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92923728A NO923728L (no) 1991-09-26 1992-09-25 Regioselektiv syntese av inflammatorisk aktive 1,5-diarylpyrazoler

Country Status (16)

Country Link
US (1) US5117054A (es)
EP (1) EP0534800A3 (es)
JP (1) JPH05320137A (es)
KR (1) KR930005982A (es)
CN (1) CN1071161A (es)
AR (1) AR248396A1 (es)
AU (1) AU2358592A (es)
CA (1) CA2079045A1 (es)
FI (1) FI924307A (es)
HU (1) HUT62862A (es)
IL (1) IL103173A0 (es)
MX (1) MX9205491A (es)
NO (1) NO923728L (es)
TW (1) TW215085B (es)
ZA (1) ZA927393B (es)
ZW (1) ZW15092A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5117054A (en) * 1991-09-26 1992-05-26 Ortho Pharmaceutical Corporation N-hydroxy, N-methyl propanamides
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
DE19723631A1 (de) * 1997-06-05 1998-12-10 Consortium Elektrochem Ind Mehrkomponentensystem zum Verändern, Abbau oder Bleichen von Lignin, ligninhaltigen Materialien oder ähnlichen Stoffen sowie Verfahren zu seiner Anwendung
EP1413575B1 (en) 1999-08-03 2006-10-11 Ortho-McNeil Pharmaceutical, Inc. Process for preparing derivatives of ¬(1,5-diaryl)pyrazol-3-yl|propanoic acid
US20060194807A1 (en) * 2003-04-03 2006-08-31 Cosford Nicholas D P Di-aryl substituted pyrazole modulators of metabotropic glutamate receptor-5

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218478A (en) * 1979-01-05 1980-08-19 Ruiko Oiwa Trichostatin as an antiprotozoal agent
US4826868A (en) * 1986-05-29 1989-05-02 Ortho Pharmaceutical Corporation 1,5-Diaryl-3-substituted pyrazoles pharmaceutical compositions and use
US4681894A (en) * 1986-09-26 1987-07-21 Ortho Pharmaceutical Corporation Hydroxamic acids and esters
US4861798A (en) * 1986-12-29 1989-08-29 Bristol-Myers Company Lipoxygenase inhibitory compounds
US4898952A (en) * 1987-05-29 1990-02-06 Ortho Pharmaceutical Corporation Regioselective synthesis of a 1,5-disubstituted pyrazole
AU611437B2 (en) * 1987-05-29 1991-06-13 Ortho Pharmaceutical Corporation Pharmacologically active 2- and 3-substituted (1',5'-diaryl-3-pyrazolyl)-n-hydroxypropanamides and method for synthesizing the same
GB9005028D0 (en) * 1990-03-06 1990-05-02 Sandoz Ltd Improvements in or relating to organic compounds
US5117054A (en) * 1991-09-26 1992-05-26 Ortho Pharmaceutical Corporation N-hydroxy, N-methyl propanamides

Also Published As

Publication number Publication date
EP0534800A3 (en) 1993-06-16
US5117054A (en) 1992-05-26
AU2358592A (en) 1993-04-01
ZA927393B (en) 1994-03-25
HU9203078D0 (en) 1992-12-28
CN1071161A (zh) 1993-04-21
CA2079045A1 (en) 1993-03-27
JPH05320137A (ja) 1993-12-03
KR930005982A (ko) 1993-04-20
NO923728D0 (no) 1992-09-25
MX9205491A (es) 1993-05-01
TW215085B (es) 1993-10-21
IL103173A0 (en) 1993-02-21
HUT62862A (en) 1993-06-28
EP0534800A2 (en) 1993-03-31
AR248396A1 (es) 1995-08-18
ZW15092A1 (en) 1994-06-15
FI924307A (fi) 1993-03-27
FI924307A0 (fi) 1992-09-25

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