FI924307A0 - Regionselektiv syntes av antiinflammatoriska 1,5-diarylpyrazollaekemedel. - Google Patents

Regionselektiv syntes av antiinflammatoriska 1,5-diarylpyrazollaekemedel.

Info

Publication number
FI924307A0
FI924307A0 FI924307A FI924307A FI924307A0 FI 924307 A0 FI924307 A0 FI 924307A0 FI 924307 A FI924307 A FI 924307A FI 924307 A FI924307 A FI 924307A FI 924307 A0 FI924307 A0 FI 924307A0
Authority
FI
Finland
Prior art keywords
regionselektiv
diarylpyrazollaekemedel
antiinflammatoriska
syntes
regionselektiv syntes
Prior art date
Application number
FI924307A
Other languages
English (en)
Other versions
FI924307A (fi
Inventor
William V Murray
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of FI924307A0 publication Critical patent/FI924307A0/fi
Publication of FI924307A publication Critical patent/FI924307A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/76Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C235/78Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58One oxygen atom, e.g. butenolide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
FI924307A 1991-09-26 1992-09-25 Regionselektiv syntes av antiinflammatoriska 1,5-diarylpyrazollaekemedel FI924307A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/766,611 US5117054A (en) 1991-09-26 1991-09-26 N-hydroxy, N-methyl propanamides

Publications (2)

Publication Number Publication Date
FI924307A0 true FI924307A0 (fi) 1992-09-25
FI924307A FI924307A (fi) 1993-03-27

Family

ID=25076968

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924307A FI924307A (fi) 1991-09-26 1992-09-25 Regionselektiv syntes av antiinflammatoriska 1,5-diarylpyrazollaekemedel

Country Status (16)

Country Link
US (1) US5117054A (fi)
EP (1) EP0534800A3 (fi)
JP (1) JPH05320137A (fi)
KR (1) KR930005982A (fi)
CN (1) CN1071161A (fi)
AR (1) AR248396A1 (fi)
AU (1) AU2358592A (fi)
CA (1) CA2079045A1 (fi)
FI (1) FI924307A (fi)
HU (1) HUT62862A (fi)
IL (1) IL103173A0 (fi)
MX (1) MX9205491A (fi)
NO (1) NO923728L (fi)
TW (1) TW215085B (fi)
ZA (1) ZA927393B (fi)
ZW (1) ZW15092A1 (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5117054A (en) * 1991-09-26 1992-05-26 Ortho Pharmaceutical Corporation N-hydroxy, N-methyl propanamides
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
DE19723631A1 (de) * 1997-06-05 1998-12-10 Consortium Elektrochem Ind Mehrkomponentensystem zum Verändern, Abbau oder Bleichen von Lignin, ligninhaltigen Materialien oder ähnlichen Stoffen sowie Verfahren zu seiner Anwendung
PT1144382E (pt) 1999-08-03 2005-02-28 Ortho Mcneil Pharm Inc Processo para a preparacao de 1,5-diaril-3-(substituido)pirazoles
CN100387594C (zh) * 2003-04-03 2008-05-14 麦克公司 二芳基取代的吡唑类代谢型谷氨酸受体-5调节剂

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218478A (en) * 1979-01-05 1980-08-19 Ruiko Oiwa Trichostatin as an antiprotozoal agent
US4826868A (en) * 1986-05-29 1989-05-02 Ortho Pharmaceutical Corporation 1,5-Diaryl-3-substituted pyrazoles pharmaceutical compositions and use
US4681894A (en) * 1986-09-26 1987-07-21 Ortho Pharmaceutical Corporation Hydroxamic acids and esters
US4861798A (en) * 1986-12-29 1989-08-29 Bristol-Myers Company Lipoxygenase inhibitory compounds
AU611437B2 (en) * 1987-05-29 1991-06-13 Ortho Pharmaceutical Corporation Pharmacologically active 2- and 3-substituted (1',5'-diaryl-3-pyrazolyl)-n-hydroxypropanamides and method for synthesizing the same
US4898952A (en) * 1987-05-29 1990-02-06 Ortho Pharmaceutical Corporation Regioselective synthesis of a 1,5-disubstituted pyrazole
GB9005028D0 (en) * 1990-03-06 1990-05-02 Sandoz Ltd Improvements in or relating to organic compounds
US5117054A (en) * 1991-09-26 1992-05-26 Ortho Pharmaceutical Corporation N-hydroxy, N-methyl propanamides

Also Published As

Publication number Publication date
EP0534800A2 (en) 1993-03-31
IL103173A0 (en) 1993-02-21
ZA927393B (en) 1994-03-25
FI924307A (fi) 1993-03-27
NO923728D0 (no) 1992-09-25
AR248396A1 (es) 1995-08-18
AU2358592A (en) 1993-04-01
CA2079045A1 (en) 1993-03-27
HUT62862A (en) 1993-06-28
US5117054A (en) 1992-05-26
ZW15092A1 (en) 1994-06-15
MX9205491A (es) 1993-05-01
HU9203078D0 (en) 1992-12-28
CN1071161A (zh) 1993-04-21
NO923728L (no) 1993-03-29
KR930005982A (ko) 1993-04-20
TW215085B (fi) 1993-10-21
JPH05320137A (ja) 1993-12-03
EP0534800A3 (en) 1993-06-16

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Legal Events

Date Code Title Description
FD Application lapsed