MX9203333A - Derivados de 2-aminopirimidina-4-carboxamida, su preparacion y su aplicacion en terapeutica. - Google Patents

Derivados de 2-aminopirimidina-4-carboxamida, su preparacion y su aplicacion en terapeutica.

Info

Publication number
MX9203333A
MX9203333A MX9203333A MX9203333A MX9203333A MX 9203333 A MX9203333 A MX 9203333A MX 9203333 A MX9203333 A MX 9203333A MX 9203333 A MX9203333 A MX 9203333A MX 9203333 A MX9203333 A MX 9203333A
Authority
MX
Mexico
Prior art keywords
therapeutics
aminopyrimidine
carboxamide
derivatives
preparation
Prior art date
Application number
MX9203333A
Other languages
English (en)
Inventor
Pascal George
Philippe Manoury
Benoit Marabout
Jacques Froissant
Jean-Pierre Merly
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of MX9203333A publication Critical patent/MX9203333A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Steroid Compounds (AREA)
MX9203333A 1991-06-27 1992-06-25 Derivados de 2-aminopirimidina-4-carboxamida, su preparacion y su aplicacion en terapeutica. MX9203333A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9107939A FR2678272B1 (fr) 1991-06-27 1991-06-27 Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
MX9203333A true MX9203333A (es) 1993-02-01

Family

ID=9414359

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203333A MX9203333A (es) 1991-06-27 1992-06-25 Derivados de 2-aminopirimidina-4-carboxamida, su preparacion y su aplicacion en terapeutica.

Country Status (23)

Country Link
US (1) US5244894A (es)
EP (1) EP0520883B1 (es)
JP (1) JP3159526B2 (es)
KR (1) KR930000508A (es)
CN (1) CN1067885A (es)
AT (1) ATE124935T1 (es)
AU (1) AU644295B2 (es)
CA (1) CA2072433A1 (es)
CZ (1) CZ9202003A3 (es)
DE (1) DE69203402T2 (es)
DK (1) DK0520883T3 (es)
ES (1) ES2077998T3 (es)
FI (1) FI922982A (es)
FR (1) FR2678272B1 (es)
GR (1) GR3017249T3 (es)
HU (1) HUT61749A (es)
IE (1) IE922094A1 (es)
IL (1) IL102332A0 (es)
MX (1) MX9203333A (es)
NO (1) NO922525L (es)
NZ (1) NZ243340A (es)
PL (1) PL295045A1 (es)
ZA (1) ZA924785B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9206371A (pt) * 1991-08-14 1995-10-17 Procter & Gamble Pharma Novas uréias cíclicas utilzáveis como agentes antirrítmicos e antifibrilatórios
DK0577470T3 (da) * 1992-07-03 1995-10-02 Synthelabo 2-amino-N(((4-(aminocarbonyl)pyrimidin-2-yl)amino)alkyl) pyrimidin-4-carboxamid-derivater, deres fremstilling og deres anvendelse i terapi
FR2703355B1 (fr) * 1993-03-29 1995-05-05 Synthelabo Dérivés de 2-aminopyrimidine-4-carboxamide, leur préparation et leur application en thérapeutique.
DE4425143A1 (de) * 1994-07-15 1996-01-18 Basf Ag Substituierte Pyrimidinverbindungen und deren Verwendung
US5688795A (en) * 1994-11-08 1997-11-18 Syntex (U.S.A.) Inc. 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists
FR2744722B1 (fr) * 1996-02-14 1998-03-13 Synthelabo Devires de 2-((3-(piperazin-1-yl)propyl)amino)pyrimidine-4- carboxamide et leur application en therapeutique
WO1999057131A1 (en) 1998-05-06 1999-11-11 Duke University Method of treating bladder and lower urinary tract syndromes
US7064211B2 (en) * 2002-03-22 2006-06-20 Eisai Co., Ltd. Hemiasterlin derivatives and uses thereof
WO2006002361A2 (en) 2004-06-24 2006-01-05 Incyte Corporation 2-methylpropanamides and their use as pharmaceuticals
EA200700117A1 (ru) 2004-06-24 2007-06-29 Инсайт Корпорейшн N-замещенные пиперидины и их применение в качестве фармацевтических препаратов
US20060009491A1 (en) * 2004-06-24 2006-01-12 Incyte Corporation Amido compounds and their use as pharmaceuticals
WO2006002349A1 (en) * 2004-06-24 2006-01-05 Incyte Corporation Amido compounds and their use as pharmaceuticals
MX2007001540A (es) * 2004-08-10 2007-04-23 Incyte Corp Compuestos amido y sus usos como farmaceuticos.
AU2013259551B2 (en) * 2012-05-09 2017-11-02 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2143730A1 (de) * 1971-09-01 1973-03-08 Byk Gulden Lomberg Chem Fab Substituierte pyridine, verfahren zu deren herstellung und sie enthaltende arzneimittel
FR2656609B1 (fr) * 1989-12-28 1992-03-27 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
FR2678271B1 (fr) * 1991-06-27 1995-01-13 Synthelabo Derives de pyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
IL102332A0 (en) 1993-01-14
EP0520883A1 (fr) 1992-12-30
DE69203402T2 (de) 1996-03-07
NO922525D0 (no) 1992-06-26
FI922982A0 (fi) 1992-06-26
CA2072433A1 (en) 1992-12-28
NO922525L (no) 1992-12-28
HU9202143D0 (en) 1992-10-28
ES2077998T3 (es) 1995-12-01
ZA924785B (en) 1993-03-31
JPH05186435A (ja) 1993-07-27
FR2678272A1 (fr) 1992-12-31
DE69203402D1 (de) 1995-08-17
CN1067885A (zh) 1993-01-13
HUT61749A (en) 1993-03-01
FR2678272B1 (fr) 1994-01-14
IE922094A1 (en) 1992-12-30
NZ243340A (en) 1994-02-25
ATE124935T1 (de) 1995-07-15
DK0520883T3 (da) 1995-12-11
FI922982A (fi) 1992-12-28
AU1858892A (en) 1993-01-07
CZ9202003A3 (en) 1993-01-13
EP0520883B1 (fr) 1995-07-12
JP3159526B2 (ja) 2001-04-23
PL295045A1 (en) 1993-03-08
AU644295B2 (en) 1993-12-02
US5244894A (en) 1993-09-14
KR930000508A (ko) 1993-01-15
GR3017249T3 (en) 1995-11-30

Similar Documents

Publication Publication Date Title
MX9203333A (es) Derivados de 2-aminopirimidina-4-carboxamida, su preparacion y su aplicacion en terapeutica.
ES2167371T3 (es) Derivados de 1h-3-aril-pirrolidin-2,4-diona espirociclicos substituidos.
FI980175A (fi) 2-sulfonamidofenonijohdannaisia
GR77595B (es)
FI942769A0 (fi) Antianginaaliset kinatsolinonit
ATE24001T1 (de) Substituierte 1-hydroxyethyl-triazolyl-derivate.
ES504206A0 (es) Procedimiento para la preparacion de nuevas 5,10-dihidro -11h-dibenzo b,e 1,4 diazepin-11-onas, sustituidas en posi- cion 5
NO922912L (no) Anvendelse av substituerte bifenyler som varmeoverfoeringsvaeske
DK316589A (da) Substituerede azacyclohexylderivater af rifamyciner
ATE123025T1 (de) 2-amino-n-(((4-(aminocarbonyl)pyrimidin-2- yl>amino>alkyl>-pyrimidin-4- carbonsäureamidderivate, ihre herstellung und ihre anwendung in der therapeutica.
SE8005493L (sv) 4-(haftalenyloxi)piperidin-derivat
ES470087A1 (es) Un procedimiento para la preparacion con compuestos organi- cos de derivados de benzacepina
DE3464602D1 (en) 4-alkylimidazole derivatives, their preparation and their application
SE8205583L (sv) Nya 5-aminoisoxazolderivat och sett for deras framstellning
DE68906827D1 (de) Phenothiazinderivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
YU48443B (sh) Novi derivati fluorhinolin-3-karboksilne kiseline postupak za njihovo dobijanje i njihova primena kao intermedijera
IL69931A (en) N-(6-chloro-pyrazin-2-yl)-4-hydroxy-2h-1,2-benzothiazine-3-carboxamide-1,1-dioxides,their preparation and pharmaceutical compositions containing them
ATE33134T1 (de) 2-aminoethyl-pyridin oder pyrazin-derivate, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ES2085738T3 (es) Derivados de tetrahidronaftaleno su preparacion y su aplicacion en terapeutica.