DK316589A - Substituerede azacyclohexylderivater af rifamyciner - Google Patents

Substituerede azacyclohexylderivater af rifamyciner Download PDF

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Publication number
DK316589A
DK316589A DK316589A DK316589A DK316589A DK 316589 A DK316589 A DK 316589A DK 316589 A DK316589 A DK 316589A DK 316589 A DK316589 A DK 316589A DK 316589 A DK316589 A DK 316589A
Authority
DK
Denmark
Prior art keywords
rifamycines
derivatives
substituted
substituted azacyclohexyl
azacyclohexyl derivatives
Prior art date
Application number
DK316589A
Other languages
English (en)
Other versions
DK163512B (da
DK163512C (da
DK316589D0 (da
Inventor
Wilhelm Kump
Keith Allan Menear
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878725118A external-priority patent/GB8725118D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK316589A publication Critical patent/DK316589A/da
Publication of DK316589D0 publication Critical patent/DK316589D0/da
Publication of DK163512B publication Critical patent/DK163512B/da
Application granted granted Critical
Publication of DK163512C publication Critical patent/DK163512C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK316589A 1987-10-27 1989-06-26 Substituerede azacyclohexylderivater af rifamyciner og salte deraf, farmaceutiske praeparater indeholdende disse forbindelser samt en fremgangsmaade til fremstilling af forbindelserne DK163512C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8725118 1987-10-27
GB878725118A GB8725118D0 (en) 1987-10-27 1987-10-27 Rifamycin derivatives
CH250088 1988-06-30
CH250088 1988-06-30
PCT/CH1988/000198 WO1989003834A1 (en) 1987-10-27 1988-10-21 Substituted azacyclohexyl derivatives
CH8800198 1988-10-21

Publications (4)

Publication Number Publication Date
DK316589A true DK316589A (da) 1989-06-26
DK316589D0 DK316589D0 (da) 1989-06-26
DK163512B DK163512B (da) 1992-03-09
DK163512C DK163512C (da) 1992-08-24

Family

ID=25690606

Family Applications (1)

Application Number Title Priority Date Filing Date
DK316589A DK163512C (da) 1987-10-27 1989-06-26 Substituerede azacyclohexylderivater af rifamyciner og salte deraf, farmaceutiske praeparater indeholdende disse forbindelser samt en fremgangsmaade til fremstilling af forbindelserne

Country Status (13)

Country Link
US (1) US5147870A (da)
EP (1) EP0314624A1 (da)
JP (1) JPH02501926A (da)
KR (1) KR890701592A (da)
DK (1) DK163512C (da)
FI (1) FI893041A0 (da)
HU (1) HU203893B (da)
IL (1) IL88134A0 (da)
NZ (1) NZ226703A (da)
PH (1) PH26387A (da)
PT (1) PT88849A (da)
WO (1) WO1989003834A1 (da)
YU (2) YU200888A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90695A0 (en) * 1988-06-30 1990-01-18 Ciba Geigy Ag Substituted azacyclohexyl derivatives
US5180718A (en) * 1989-03-02 1993-01-19 Ciba-Geigy Corporation Acyl derivatives of oxazolorifamycins
HU204835B (en) * 1989-04-26 1992-02-28 Ciba Geigy Ag New process for producing rifamycin compounds
EP0434621A3 (en) * 1989-12-21 1992-02-26 Ciba-Geigy Ag Rifamycin derivatives and processes for the manufacture thereof
EP0475895A1 (en) * 1990-08-31 1992-03-18 Ciba-Geigy Ag Acyl derivatives of rifamycins and their use as medicaments
EP0475896A1 (en) * 1990-08-31 1992-03-18 Ciba-Geigy Ag Polycyclic compounds
US20040176404A1 (en) * 2002-12-12 2004-09-09 Sayada Chalom B. Methods and reagents for treating or preventing atherosclerosis and diseases associated therewith

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005077A (en) * 1965-08-24 1977-01-25 Ciba-Geigy Corporation Antibiotically active compounds
US4261891A (en) * 1965-08-24 1981-04-14 Ciba-Geigy Corporation Antibiotically active rifamycin derivatives
IT1135270B (it) * 1980-04-12 1986-08-20 Erba Farmitalia 3-amidino-ansamicine
MC1819A1 (fr) * 1985-10-18 1988-03-18 Ciba Geigy Ag Composes 4-benzyl-piperazinyl substitues
DE3545538A1 (de) * 1985-12-21 1987-07-02 Audi Ag Vorrichtung mit einem hubgestell zum bearbeiten von werkstuecken
US4876258A (en) * 1987-08-13 1989-10-24 Ciba-Geigy Corporation Biphenylyl compounds
WO1989002894A1 (en) * 1987-09-25 1989-04-06 Ciba-Geigy Ag Diacyl derivatives of 4-(trialkylbenzyl)-piperazinyl compounds
GB8725118D0 (en) * 1987-10-27 1987-12-02 Ciba Geigy Ag Rifamycin derivatives
US5003070A (en) * 1988-06-30 1991-03-26 Ciba-Geigy Corporation Substituted azacyclohexyl derivatives of rifamycins
IL90695A0 (en) * 1988-06-30 1990-01-18 Ciba Geigy Ag Substituted azacyclohexyl derivatives
HU204835B (en) * 1989-04-26 1992-02-28 Ciba Geigy Ag New process for producing rifamycin compounds

Also Published As

Publication number Publication date
HU203893B (en) 1991-10-28
NZ226703A (en) 1991-02-26
KR890701592A (ko) 1989-12-21
DK163512B (da) 1992-03-09
WO1989003834A1 (en) 1989-05-05
EP0314624A1 (de) 1989-05-03
YU173289A (en) 1990-02-28
FI893041A (fi) 1989-06-21
IL88134A0 (en) 1989-06-30
HU885893D0 (en) 1990-02-28
FI893041A0 (fi) 1989-06-21
YU200888A (en) 1990-02-28
JPH02501926A (ja) 1990-06-28
US5147870A (en) 1992-09-15
DK163512C (da) 1992-08-24
DK316589D0 (da) 1989-06-26
HUT55399A (en) 1991-05-28
PT88849A (pt) 1989-07-31
PH26387A (en) 1992-07-02

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
PBP Patent lapsed