MX394958B - Estimuladores de guanilato ciclasa soluble (sgc) biciclicos fusionados - Google Patents

Estimuladores de guanilato ciclasa soluble (sgc) biciclicos fusionados

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Publication number
MX394958B
MX394958B MX2021007580A MX2021007580A MX394958B MX 394958 B MX394958 B MX 394958B MX 2021007580 A MX2021007580 A MX 2021007580A MX 2021007580 A MX2021007580 A MX 2021007580A MX 394958 B MX394958 B MX 394958B
Authority
MX
Mexico
Prior art keywords
fused bicyclic
sgc stimulators
concentration
increase
sgc
Prior art date
Application number
MX2021007580A
Other languages
English (en)
Spanish (es)
Other versions
MX2021007580A (es
Inventor
Ara Mermerian
G-Yoon Jamie Im
Glen Robert Rennie
Joon Jung
Karthik Iyer
Kim Tang
Lei Jia
Paul Allan Renhowe
Peter Germano
Rajesh R Iyengar
Takashi Nakai
Thomas Wai-Ho Lee
Timothy Claude Barden
Original Assignee
Cyclerion Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyclerion Therapeutics Inc filed Critical Cyclerion Therapeutics Inc
Publication of MX2021007580A publication Critical patent/MX2021007580A/es
Publication of MX394958B publication Critical patent/MX394958B/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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MX2021007580A 2016-09-02 2017-09-01 Estimuladores de guanilato ciclasa soluble (sgc) biciclicos fusionados MX394958B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662382942P 2016-09-02 2016-09-02
US201662423445P 2016-11-17 2016-11-17
US201762468598P 2017-03-08 2017-03-08
US201762482486P 2017-04-06 2017-04-06
PCT/US2017/049834 WO2018045276A1 (en) 2016-09-02 2017-09-01 Fused bicyclic sgc stimulators

Publications (2)

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MX2021007580A MX2021007580A (es) 2022-08-23
MX394958B true MX394958B (es) 2025-03-24

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MX2021007580A MX394958B (es) 2016-09-02 2017-09-01 Estimuladores de guanilato ciclasa soluble (sgc) biciclicos fusionados
MX2019002313A MX383782B (es) 2016-09-02 2017-09-01 Estimuladores de guanilato ciclasa soluble (sgc) biciclicos fusionados.
MX2021007579A MX2021007579A (es) 2016-09-02 2019-02-26 Estimuladores de guanilato ciclasa soluble (sgc) biciclicos fusionados.

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MX2021007579A MX2021007579A (es) 2016-09-02 2019-02-26 Estimuladores de guanilato ciclasa soluble (sgc) biciclicos fusionados.

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