MX391164B - Metodo para producir compuesto opticamente activo - Google Patents
Metodo para producir compuesto opticamente activoInfo
- Publication number
- MX391164B MX391164B MX2019014256A MX2019014256A MX391164B MX 391164 B MX391164 B MX 391164B MX 2019014256 A MX2019014256 A MX 2019014256A MX 2019014256 A MX2019014256 A MX 2019014256A MX 391164 B MX391164 B MX 391164B
- Authority
- MX
- Mexico
- Prior art keywords
- salt
- compound
- optically active
- active compound
- producing optically
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 5
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- FUXJMHXHGDAHPD-UHFFFAOYSA-N pyrimidine-2-carboxamide Chemical class NC(=O)C1=NC=CC=N1 FUXJMHXHGDAHPD-UHFFFAOYSA-N 0.000 abstract 1
- 238000006722 reduction reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017106280 | 2017-05-30 | ||
| PCT/IB2018/053822 WO2018220533A2 (ja) | 2017-05-30 | 2018-05-29 | 光学活性化合物の製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019014256A MX2019014256A (es) | 2022-03-31 |
| MX391164B true MX391164B (es) | 2025-03-21 |
Family
ID=64454503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019014256A MX391164B (es) | 2017-05-30 | 2018-05-29 | Metodo para producir compuesto opticamente activo |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10988469B2 (https=) |
| EP (2) | EP3632441B1 (https=) |
| JP (2) | JP7102233B2 (https=) |
| KR (1) | KR102754527B1 (https=) |
| CN (2) | CN111032047B (https=) |
| AU (1) | AU2018276192B2 (https=) |
| CA (1) | CA3065683A1 (https=) |
| EA (1) | EA039880B1 (https=) |
| ES (1) | ES2986461T3 (https=) |
| IL (1) | IL270983B (https=) |
| MX (1) | MX391164B (https=) |
| WO (1) | WO2018220533A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX391164B (es) | 2017-05-30 | 2025-03-21 | Dot Therapeutics 1 Inc | Metodo para producir compuesto opticamente activo |
| CN113557227A (zh) * | 2019-03-27 | 2021-10-26 | 协和医药化工股份有限公司 | 前列腺素的制造方法 |
| AU2021376286A1 (en) * | 2020-11-06 | 2023-06-22 | Dana-Farber Cancer Institute, Inc. | Raf inhibitor for treating low grade glioma |
| CN114685564B (zh) * | 2020-12-27 | 2023-09-22 | 西北大学 | 新型亚磷酰胺配体及其合成方法和应用 |
| EP4377296A1 (en) | 2021-07-26 | 2024-06-05 | Arvinas Operations, Inc. | Methods of manufacturing a bifunctional compound |
| CN117567388B (zh) * | 2023-11-14 | 2024-04-16 | 济南悟通生物科技有限公司 | 一种2-乙酰基-5-噻唑甲酸的合成方法 |
| WO2026028053A2 (en) | 2024-07-27 | 2026-02-05 | Assia Chemical Industries Ltd. | Process for the preparation of tovorafenib |
| CN119241530B (zh) * | 2024-09-20 | 2026-04-10 | 武汉九州钰民医药科技有限公司 | 一种Tovorafenib的药物合成工艺 |
| CN119241529B (zh) * | 2024-09-20 | 2026-04-10 | 武汉九州钰民医药科技有限公司 | 一种Tovorafenib的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6764842B2 (en) * | 2001-03-28 | 2004-07-20 | Merck & Co., Inc. | Enantioselective bioreduction for the preparation of integrin receptor antagonist intermediates |
| TW200303304A (en) * | 2002-02-18 | 2003-09-01 | Astrazeneca Ab | Chemical compounds |
| US7754889B2 (en) * | 2004-03-29 | 2010-07-13 | Takasago International Corporation | Optically active transition metal-diamine compound and process for producing optically active alcohol with the same |
| TWI345568B (en) * | 2004-04-02 | 2011-07-21 | Mitsubishi Tanabe Pharma Corp | Tetrahydronaphthyridine derivatives and a process for preparing the same |
| AR067354A1 (es) * | 2007-06-29 | 2009-10-07 | Sunesis Pharmaceuticals Inc | Compuestos utiles como inhibidores de la raf quinasa |
| EP2167497A2 (en) * | 2007-06-29 | 2010-03-31 | Sunesis Pharmaceuticals, Inc. | Heterocyclic compounds useful as raf kinase inhibitors |
| MX351657B (es) * | 2012-03-14 | 2017-10-23 | Merck Sharp & Dohme | Sales de alcaloide de cinchona bis-cuaternarias como catalizadores de transferencia de fase asimétrica. |
| CN107880075A (zh) | 2012-03-28 | 2018-04-06 | 武田药品工业株式会社 | 铑催化剂和制备胺化合物的方法 |
| TWI602803B (zh) * | 2013-03-29 | 2017-10-21 | 第一三共股份有限公司 | 光學活性二胺衍生物之製造方法 |
| WO2015178846A1 (en) * | 2014-05-20 | 2015-11-26 | Sp Process Development Ab | Process for the preparation of chiral amines from prochiral ketones |
| JP6638363B2 (ja) | 2015-12-11 | 2020-01-29 | 株式会社大林組 | 掘削装置および杭孔の拡径方法 |
| CN105524111B (zh) * | 2016-01-25 | 2017-10-27 | 西北农林科技大学 | 手性亚磷酰胺单齿配体及其合成方法与应用 |
| MX391164B (es) | 2017-05-30 | 2025-03-21 | Dot Therapeutics 1 Inc | Metodo para producir compuesto opticamente activo |
-
2018
- 2018-05-29 MX MX2019014256A patent/MX391164B/es unknown
- 2018-05-29 EA EA201992709A patent/EA039880B1/ru unknown
- 2018-05-29 CN CN201880050913.0A patent/CN111032047B/zh active Active
- 2018-05-29 EP EP18808978.3A patent/EP3632441B1/en active Active
- 2018-05-29 KR KR1020197038460A patent/KR102754527B1/ko active Active
- 2018-05-29 AU AU2018276192A patent/AU2018276192B2/en active Active
- 2018-05-29 CA CA3065683A patent/CA3065683A1/en active Pending
- 2018-05-29 ES ES18808978T patent/ES2986461T3/es active Active
- 2018-05-29 EP EP24180862.5A patent/EP4406609A3/en active Pending
- 2018-05-29 US US16/617,914 patent/US10988469B2/en active Active
- 2018-05-29 WO PCT/IB2018/053822 patent/WO2018220533A2/ja not_active Ceased
- 2018-05-29 CN CN202311299784.8A patent/CN117447464A/zh active Pending
- 2018-05-30 JP JP2018103970A patent/JP7102233B2/ja active Active
-
2019
- 2019-11-27 IL IL270983A patent/IL270983B/en unknown
-
2021
- 2021-02-19 US US17/180,127 patent/US12129249B2/en active Active
-
2022
- 2022-05-11 JP JP2022078462A patent/JP7420865B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3632441A2 (en) | 2020-04-08 |
| JP7420865B2 (ja) | 2024-01-23 |
| IL270983B (en) | 2022-03-01 |
| US20210347769A1 (en) | 2021-11-11 |
| KR102754527B1 (ko) | 2025-01-14 |
| JP2018203733A (ja) | 2018-12-27 |
| EP4406609A3 (en) | 2024-10-02 |
| AU2018276192A1 (en) | 2020-01-16 |
| AU2018276192B2 (en) | 2022-05-19 |
| EP4406609A2 (en) | 2024-07-31 |
| US20200317659A1 (en) | 2020-10-08 |
| MX2019014256A (es) | 2022-03-31 |
| JP7102233B2 (ja) | 2022-07-19 |
| KR20200013707A (ko) | 2020-02-07 |
| CN117447464A (zh) | 2024-01-26 |
| EP3632441A4 (en) | 2021-01-13 |
| WO2018220533A3 (ja) | 2019-02-28 |
| ES2986461T3 (es) | 2024-11-11 |
| CN111032047A (zh) | 2020-04-17 |
| EA201992709A1 (ru) | 2020-04-23 |
| WO2018220533A2 (ja) | 2018-12-06 |
| CA3065683A1 (en) | 2018-12-06 |
| EP3632441C0 (en) | 2024-07-17 |
| CN111032047B (zh) | 2023-10-27 |
| BR112019025355A2 (pt) | 2020-06-23 |
| JP2022116043A (ja) | 2022-08-09 |
| US10988469B2 (en) | 2021-04-27 |
| EA039880B1 (ru) | 2022-03-23 |
| US12129249B2 (en) | 2024-10-29 |
| EP3632441B1 (en) | 2024-07-17 |
| IL270983A (en) | 2020-01-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX391164B (es) | Metodo para producir compuesto opticamente activo | |
| PH12017502265A1 (en) | System and method for biomass growth and processing | |
| MY163187A (en) | Novel imidazo-oxazine compound or salt thereof | |
| TN2013000347A1 (en) | Production method of optically active dihydrobenzofuran derivative | |
| WO2015031441A3 (en) | Microorganisms engineered to use unconventional sources of phosphorus or sulfur | |
| PH12018500582A1 (en) | Crosslinked nucleic acid guna, method for producing same, and intermediate compound | |
| MX367578B (es) | Proceso para producir derivado de diazabiciclooctano y su intermediario. | |
| MX2016003737A (es) | Microorganismo recombinante para la mejora de produccion de productos quimicos finos. | |
| PH12016501094A1 (en) | Recombinant microorganism for improved production of fine chemicals | |
| MY188962A (en) | A microorganism of genus corynebacterium having an ability to produce l-arginine and an method for producing l-arginine using the same | |
| BR112015020904A2 (pt) | microrganismos e métodos para produção de butadieno e compostos relacionados por assimilação de formiato | |
| MY189932A (en) | Recombinant microorganism for improved production of alanine | |
| MY182946A (en) | Production of organic acids by fermentation at low ph | |
| CY1120380T1 (el) | Διαδικασια για την παρασκευη παραγωγων 4,6-δις(αρυλοξυ)πυριμιδινης | |
| IN2015DN02381A (https=) | ||
| PH12018500150B1 (en) | Microorganisms for producing putrescine or ornithine and process for producing putrescine or ornithine using them | |
| WO2015034950A3 (en) | Smile correction using fac lens deformation | |
| MX383967B (es) | Microorganismo del género corynebacterium productor de l-arginina y método para producir l-arginina usando el mismo. | |
| MY193458A (en) | Microorganism for producing a mycosporine-like amino acid and method for producing a mycosporine-like amino acid using the same | |
| MY185835A (en) | Novel variant of o-phosphoserine exporter and method of producing o-phosphoserine, cysteine, and its derivatives using the same | |
| MY176584A (en) | Gluconate repressor variant, microorganism containing the same producing l-lysine, and method for producing l-lysine | |
| EA201791659A1 (ru) | Компьютеризированный способ создания модели процесса ферментации | |
| MY174840A (en) | Microorganism producing o-acetyl-homoserine, and method for producing o-acetyl-homoserine by using same | |
| BR112015000345A2 (pt) | geração eletroquímica de derivados de ureia clorada | |
| MY194572A (en) | Self-sufficient process for the production of biomass hydrolysate with reduced salt content |