MX390806B - Proteasa de cisteina. - Google Patents
Proteasa de cisteina.Info
- Publication number
- MX390806B MX390806B MX2017010390A MX2017010390A MX390806B MX 390806 B MX390806 B MX 390806B MX 2017010390 A MX2017010390 A MX 2017010390A MX 2017010390 A MX2017010390 A MX 2017010390A MX 390806 B MX390806 B MX 390806B
- Authority
- MX
- Mexico
- Prior art keywords
- cysteine protease
- igg
- vivo
- methods
- polypeptide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201502306A GB201502306D0 (en) | 2015-02-12 | 2015-02-12 | Protein |
| PCT/EP2016/053052 WO2016128558A1 (en) | 2015-02-12 | 2016-02-12 | Cysteine protease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017010390A MX2017010390A (es) | 2017-12-07 |
| MX390806B true MX390806B (es) | 2025-03-21 |
Family
ID=52781456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017010390A MX390806B (es) | 2015-02-12 | 2016-02-12 | Proteasa de cisteina. |
Country Status (23)
| Country | Link |
|---|---|
| US (5) | US10696959B2 (enExample) |
| EP (2) | EP3256580B1 (enExample) |
| JP (1) | JP6961486B2 (enExample) |
| KR (1) | KR102524613B1 (enExample) |
| CN (2) | CN107532156A (enExample) |
| AU (2) | AU2016217800B2 (enExample) |
| BR (1) | BR112017017284A2 (enExample) |
| CA (1) | CA2976003A1 (enExample) |
| CL (1) | CL2017002065A1 (enExample) |
| CO (1) | CO2017009061A2 (enExample) |
| DK (1) | DK3256580T3 (enExample) |
| EA (1) | EA035130B1 (enExample) |
| ES (1) | ES2927234T3 (enExample) |
| GB (1) | GB201502306D0 (enExample) |
| IL (1) | IL253938B (enExample) |
| LT (1) | LT3256580T (enExample) |
| MX (1) | MX390806B (enExample) |
| MY (1) | MY188696A (enExample) |
| PL (1) | PL3256580T3 (enExample) |
| PT (1) | PT3256580T (enExample) |
| SG (1) | SG11201706346QA (enExample) |
| WO (1) | WO2016128558A1 (enExample) |
| ZA (1) | ZA201705113B (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201413240D0 (en) * | 2014-07-25 | 2014-09-10 | Hansa Medical Ab | Method |
| GB201502306D0 (en) * | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
| GB201502305D0 (en) | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
| US20210228738A1 (en) | 2017-07-17 | 2021-07-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins |
| JP7425738B2 (ja) | 2018-04-03 | 2024-01-31 | ギンコ バイオワークス インコーポレイテッド | 眼組織を標的とするウイルスベクター |
| CN112272672A (zh) | 2018-04-03 | 2021-01-26 | 斯特里迪比奥公司 | 抗体逃避性病毒载体 |
| WO2019195444A1 (en) | 2018-04-03 | 2019-10-10 | Stridebio, Inc. | Antibody-evading virus vectors |
| CA3133453A1 (en) | 2019-03-21 | 2020-09-24 | Daniel Mccoy | Recombinant adeno-associated virus vectors |
| EP4038194A1 (en) | 2019-10-04 | 2022-08-10 | Ultragenyx Pharmaceutical Inc. | Methods for improved therapeutic use of recombinant aav |
| AU2020367532A1 (en) | 2019-10-17 | 2022-05-12 | Ginkgo Bioworks, Inc. | Adeno-associated viral vectors for treatment of Niemann-Pick disease type C |
| EP4524236A3 (en) | 2019-12-06 | 2025-07-23 | Regeneron Pharmaceuticals, Inc. | Anti-vegf protein compositions and methods for producing the same |
| BR112022015921A2 (pt) | 2020-02-14 | 2022-10-04 | Ultragenyx Pharmaceutical Inc | Terapia gênica para tratar o transtorno de deficiência de cdkl5 |
| GB202002072D0 (en) | 2020-02-14 | 2020-04-01 | Hansa Biopharma AB | immunoglobulin detection and associated therapies |
| GB202003129D0 (en) * | 2020-03-04 | 2020-04-15 | Hansa Biopharma AB | Conditioning regimen for transplant of stem cells |
| AU2021268026A1 (en) | 2020-05-08 | 2023-01-19 | Regeneron Pharmaceuticals, Inc. | VEGF traps and mini-traps and methods for treating ocular disorders and cancer |
| GB202007431D0 (en) * | 2020-05-19 | 2020-07-01 | Hansa Biopharma AB | Cysteine protease |
| GB202007434D0 (en) | 2020-05-19 | 2020-07-01 | Hansa Biopharma AB | Methods |
| WO2021244628A1 (zh) | 2020-06-05 | 2021-12-09 | 上海宝济药业有限公司 | 一种酶和病毒的药物组合及其应用 |
| WO2021254479A1 (zh) * | 2020-06-18 | 2021-12-23 | 上海宝济药业有限公司 | 一种免疫球蛋白降解酶IdeE的突变体 |
| KR20230068444A (ko) | 2020-08-19 | 2023-05-17 | 사렙타 쎄러퓨틱스 인코퍼레이티드 | 레트 증후군의 치료를 위한 아데노 관련 바이러스 벡터 |
| AU2021358957A1 (en) | 2020-10-07 | 2023-06-08 | AskBio Inc. | Therapeutic adeno-associated virus delivery of fukutin related protein (fkrp) for treating dystroglycanopathy. disorders including limb girdle 21 |
| JP2024515626A (ja) | 2021-04-16 | 2024-04-10 | アスクレピオス バイオファーマシューティカル， インコーポレイテッド | 血液脳関門を横断し低減された液性応答を惹起する合理的ポリプロイドａａｖビリオン |
| EP4079848A1 (en) | 2021-04-22 | 2022-10-26 | Genovis Ab | Immunoglobulin cleaving enzyme |
| JP2024531138A (ja) | 2021-08-11 | 2024-08-29 | ウルトラジェニックス ファーマシューティカル インコーポレイテッド | 筋ジストロフィーを処置するための組成物および方法 |
| CN119013396A (zh) | 2021-11-15 | 2024-11-22 | 汉莎生物制药股份有限公司 | 增强过继性细胞转移免疫疗法的方法 |
| WO2023109928A1 (zh) | 2021-12-16 | 2023-06-22 | 上海宝济药业有限公司 | 抗免疫球蛋白降解酶酶切的Fc变体 |
| WO2023116817A1 (zh) * | 2021-12-22 | 2023-06-29 | 上海宝济药业有限公司 | 一种免疫球蛋白降解酶IdeE的突变体的用途 |
| EP4275701A1 (en) | 2022-05-13 | 2023-11-15 | Hansa Biopharma AB | Conditioning regimen for cell transplant |
| EP4302770A1 (en) | 2022-07-08 | 2024-01-10 | Hansa Biopharma AB | Regimen for enzymatic desensitisation |
| EP4349365A1 (en) | 2022-10-07 | 2024-04-10 | Hansa Biopharma AB | Co-treatment for gene therapy |
| CN115873833B (zh) * | 2022-11-08 | 2024-08-16 | 上海泰昶生物技术有限公司 | 生产免疫球蛋白g降解酶的工程菌株和工艺 |
| CN115998690B (zh) * | 2022-11-10 | 2024-07-26 | 上海泰昶生物技术有限公司 | 包含免疫球蛋白g降解酶的冻干制剂及其制备工艺 |
| EP4619443A2 (en) | 2022-11-18 | 2025-09-24 | Seismic Therapeutic, Inc. | Fc fusion molecules and uses thereof |
| US12129499B2 (en) | 2023-01-06 | 2024-10-29 | Seismic Therapeutic, Inc. | Protease variants and uses thereof |
| WO2025072144A1 (en) * | 2023-09-27 | 2025-04-03 | Osprey Biopharmaceuticals, Inc. | Polypeptides having human igg cleavage activity |
| WO2025256978A1 (en) | 2024-06-13 | 2025-12-18 | Bayer Aktiengesellschaft | Variants of igm and igg cleaving enzymes |
| WO2025256977A1 (en) | 2024-06-13 | 2025-12-18 | Bayer Aktiengesellschaft | Novel igm and igg cleaving enzymes |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| EP1343895B1 (en) | 2000-12-21 | 2008-06-18 | ID Biomedical Corporation | Streptococcus pyogenes antigens and corresponding dna fragments |
| GB0130228D0 (en) | 2001-12-18 | 2002-02-06 | Hansa Medica Ab | Protein |
| JP3726095B2 (ja) * | 2002-11-29 | 2005-12-14 | 森永乳業株式会社 | プロテアーゼ阻害剤 |
| PL1601770T3 (pl) * | 2003-03-04 | 2010-02-26 | Intercell Ag | Antygeny Streptococcus pyogenes |
| ES2380950T3 (es) | 2005-06-09 | 2012-05-21 | Hansa Medical Ab | Uso de la proteinasa IdeS ( de S, pyogenes) para tratar enfermedades autoinmunitarias y rechazo de injerto |
| GB0511769D0 (en) * | 2005-06-09 | 2005-07-20 | Hansa Medical Ab | Treatment |
| US7544577B2 (en) * | 2005-08-26 | 2009-06-09 | International Business Machines Corporation | Mobility enhancement in SiGe heterojunction bipolar transistors |
| JP5722627B2 (ja) | 2007-09-14 | 2015-05-27 | ジェノビス エービー | ＦＣガンマ受容体−ＩｇＧ複合体の解離、ならびにＩｇＧの精製および検出のための方法およびキット |
| JP2011506433A (ja) * | 2007-12-13 | 2011-03-03 | インターバック アーベー | 改変された免疫組成物 |
| CN101903401B (zh) | 2007-12-21 | 2013-06-05 | 罗切格利卡特公司 | 抗体的稳定性试验 |
| SG173589A1 (en) * | 2009-02-09 | 2011-09-29 | Roche Glycart Ag | Immunoglobulin glycosylation pattern analysis |
| CN103068838B (zh) | 2010-05-26 | 2016-03-02 | 英特瓦克公司 | 基于重组蛋白的抗链球菌感染疫苗 |
| GB201115841D0 (en) * | 2011-09-13 | 2011-10-26 | Genovis Ab | Protein and method |
| GB201201314D0 (en) | 2012-01-26 | 2012-03-07 | Isis Innovation | Composition |
| CN103214549B (zh) * | 2013-01-15 | 2015-08-05 | 珠海市丽珠单抗生物技术有限公司 | 一种还原免疫球蛋白的方法及其试剂盒 |
| GB201316744D0 (en) | 2013-09-20 | 2013-11-06 | Genovis Ab | Method |
| GB201413240D0 (en) | 2014-07-25 | 2014-09-10 | Hansa Medical Ab | Method |
| GB201502305D0 (en) | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
| GB201502306D0 (en) * | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
-
2015
- 2015-02-12 GB GB201502306A patent/GB201502306D0/en not_active Ceased
-
2016
- 2016-02-12 KR KR1020177025560A patent/KR102524613B1/ko active Active
- 2016-02-12 WO PCT/EP2016/053052 patent/WO2016128558A1/en not_active Ceased
- 2016-02-12 BR BR112017017284A patent/BR112017017284A2/pt not_active Application Discontinuation
- 2016-02-12 PL PL16707653.8T patent/PL3256580T3/pl unknown
- 2016-02-12 US US15/550,309 patent/US10696959B2/en active Active
- 2016-02-12 EP EP16707653.8A patent/EP3256580B1/en active Active
- 2016-02-12 DK DK16707653.8T patent/DK3256580T3/da active
- 2016-02-12 MX MX2017010390A patent/MX390806B/es unknown
- 2016-02-12 PT PT167076538T patent/PT3256580T/pt unknown
- 2016-02-12 EP EP22174919.5A patent/EP4108768A1/en active Pending
- 2016-02-12 AU AU2016217800A patent/AU2016217800B2/en active Active
- 2016-02-12 MY MYPI2017001124A patent/MY188696A/en unknown
- 2016-02-12 CA CA2976003A patent/CA2976003A1/en active Pending
- 2016-02-12 CN CN201680021601.8A patent/CN107532156A/zh active Pending
- 2016-02-12 JP JP2017542896A patent/JP6961486B2/ja active Active
- 2016-02-12 EA EA201791773A patent/EA035130B1/ru not_active IP Right Cessation
- 2016-02-12 LT LTEPPCT/EP2016/053052T patent/LT3256580T/lt unknown
- 2016-02-12 ES ES16707653T patent/ES2927234T3/es active Active
- 2016-02-12 SG SG11201706346QA patent/SG11201706346QA/en unknown
- 2016-02-12 CN CN202111557859.9A patent/CN114231512B/zh active Active
-
2017
- 2017-07-27 ZA ZA2017/05113A patent/ZA201705113B/en unknown
- 2017-08-10 IL IL253938A patent/IL253938B/en active IP Right Grant
- 2017-08-11 CL CL2017002065A patent/CL2017002065A1/es unknown
- 2017-09-04 CO CONC2017/0009061A patent/CO2017009061A2/es unknown
-
2020
- 2020-05-20 US US16/879,324 patent/US11214784B2/en active Active
-
2021
- 2021-11-11 AU AU2021266293A patent/AU2021266293B2/en active Active
- 2021-12-14 US US17/644,315 patent/US11667905B2/en active Active
-
2023
- 2023-05-16 US US18/318,455 patent/US12359183B2/en active Active
-
2025
- 2025-06-09 US US19/232,657 patent/US20250304937A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX390806B (es) | Proteasa de cisteina. | |
| ZA201705114B (en) | Cysteine protease | |
| PH12019501405A1 (en) | Anti-neuropilin antigen-binding proteins and methods of use thereof | |
| IL256614B (en) | Transthyretin (ttr) irna compositions and methods of use thereof for treating or preventing ttr-associated diseases | |
| EA201792583A1 (ru) | Способы и композиции для ингибирования взаимодействия менина с белками mll | |
| MY192226A (en) | Anti-tigit antigen-binding proteins and methods of use thereof | |
| PH12017501077A1 (en) | Compositions and methods for antibodies targeting bmp6 | |
| EA201691582A1 (ru) | Новые фармацевтические препараты | |
| EA201790273A1 (ru) | Флагеллиновые композиции и их применение | |
| BR112016028891A2 (pt) | processos de trens de sementes e usos dos mesmos | |
| EA201890185A1 (ru) | Способы лечения опосредованных гепсидином нарушений | |
| EA201891539A1 (ru) | Соединения, ингибирующие металлоферменты | |
| EA201890747A1 (ru) | Способы лечения воспалительных заболеваний | |
| EA201792157A1 (ru) | Имидазопиразиноны в качестве ингибиторов pde1 | |
| MX2023006415A (es) | Anticuerpos, usos y metodos. | |
| BR112018002382A2 (pt) | novos anticorpos anti-gvpi humano e usos dos mesmos | |
| EA201790893A1 (ru) | Способы лечения офтальмологических расстройств | |
| BR112016019389A2 (pt) | vacina, e, peptídeo | |
| EP3597040A4 (en) | PLANT DISEASE CONTROL AGENT | |
| EA201691335A1 (ru) | Гексагидрофуропирролы в качестве ингибиторов pde1 | |
| PH12016501326A1 (en) | (s)-3'-methyl-abscisic acid and esters thereof | |
| MX383460B (es) | Derivados peptidicos novedosos y sus usos. | |
| MX374598B (es) | Complejo de tanato de sitagliptina. | |
| MX2017013601A (es) | Un proceso de etapas multiples para la produccion de no. | |
| EP3226883C0 (en) | COMPOSITIONS FOR THE TREATMENT OF DEGENERATIVE DISEASES OF THE RETINA |