MX388231B - Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal. - Google Patents
Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal.Info
- Publication number
- MX388231B MX388231B MX2017005126A MX2017005126A MX388231B MX 388231 B MX388231 B MX 388231B MX 2017005126 A MX2017005126 A MX 2017005126A MX 2017005126 A MX2017005126 A MX 2017005126A MX 388231 B MX388231 B MX 388231B
- Authority
- MX
- Mexico
- Prior art keywords
- prognosis
- diagnosis
- kidney
- compositions
- methods
- Prior art date
Links
- 206010061481 Renal injury Diseases 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000004393 prognosis Methods 0.000 title abstract 2
- 208000001647 Renal Insufficiency Diseases 0.000 title 1
- 201000006370 kidney failure Diseases 0.000 title 1
- 208000037806 kidney injury Diseases 0.000 title 1
- 238000003556 assay Methods 0.000 abstract 2
- 102100023705 C-C motif chemokine 14 Human genes 0.000 abstract 1
- 101710112614 C-C motif chemokine 14 Proteins 0.000 abstract 1
- 102100023700 C-C motif chemokine 16 Human genes 0.000 abstract 1
- 101710112632 C-C motif chemokine 16 Proteins 0.000 abstract 1
- 102100037236 Tyrosine-protein kinase receptor UFO Human genes 0.000 abstract 1
- 101710192735 Tyrosine-protein kinase receptor UFO Proteins 0.000 abstract 1
- 239000000104 diagnostic biomarker Substances 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 239000000092 prognostic biomarker Substances 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/521—Chemokines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
La presente invención se refiere a métodos y composiciones para controlar, diagnosticar, pronosticar y determinar los regímenes de tratamiento en sujetos que padecen de o que se sospecha que tienen lesión renal. En particular, la lesión se refiere al uso de ensayos que detectan uno o más de motivo C-C de quimiocina 16, motivo C-C de quimiocina 14, y receptor de proteína cinasa tirosina UFO como ensayos de biomarcador de diagnóstico y pronóstico en lesiones renales.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462066313P | 2014-10-20 | 2014-10-20 | |
| US201462066316P | 2014-10-20 | 2014-10-20 | |
| US201462066310P | 2014-10-20 | 2014-10-20 | |
| PCT/US2015/056462 WO2016064877A2 (en) | 2014-10-20 | 2015-10-20 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017005126A MX2017005126A (es) | 2017-09-15 |
| MX388231B true MX388231B (es) | 2025-03-19 |
Family
ID=55761743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017005126A MX388231B (es) | 2014-10-20 | 2015-10-20 | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11333671B2 (es) |
| EP (2) | EP3968022A1 (es) |
| JP (4) | JP6792553B2 (es) |
| KR (1) | KR102431003B1 (es) |
| CN (2) | CN107003301B (es) |
| AU (2) | AU2015336069B2 (es) |
| BR (1) | BR112017008218A2 (es) |
| CA (1) | CA2965153C (es) |
| EA (1) | EA201790696A1 (es) |
| ES (1) | ES2907551T3 (es) |
| MX (1) | MX388231B (es) |
| PT (1) | PT3210018T (es) |
| WO (1) | WO2016064877A2 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3968022A1 (en) | 2014-10-20 | 2022-03-16 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| MX2019008260A (es) * | 2017-01-12 | 2020-01-27 | Astute Medical Inc | Metodos y composiciones para la evaluacion y tratamiento de lesion renal e insuficiencia renal con base en la medicion del ligando 14 de quimiocina de la porcion c-c. |
| US11346846B2 (en) | 2017-02-06 | 2022-05-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP3732196A4 (en) | 2017-12-28 | 2022-01-05 | Astute Medical, Inc. | ANTIBODIES AND ASSAYS FOR CCL14 |
| JP7221985B2 (ja) * | 2018-04-02 | 2023-02-14 | ポトレロ メディカル,インコーポレイテッド | 体液の排出および分析、並びに健康の評価のためのシステム |
| US12114978B2 (en) | 2018-04-02 | 2024-10-15 | Potrero Medical, Inc. | Systems, devices and methods for draining and analyzing bodily fluids and assessing health |
| CA3141817A1 (en) * | 2019-05-24 | 2020-12-03 | Astute Medical, Inc. | Methods for evaluation and treatment of renal injury based on c-c motif chemokine ligand 14 measurement |
| US20230290457A1 (en) * | 2020-03-23 | 2023-09-14 | Biocogniv Inc. | Artificial intelligence medical device |
| GB2596142B (en) * | 2020-06-19 | 2023-11-29 | Secr Defence | Methods and associated uses, kits and systems for assessing sepsis |
| EP4247395A4 (en) * | 2020-11-18 | 2024-09-18 | Astute Medical, Inc. | Methods and compositions for treatment of renal injury and renal failure |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| JPH05504841A (ja) | 1990-09-14 | 1993-07-22 | バイオサイト・ダイアグノスティックス・インコーポレイテッド | リガンドレセプター及びリガンドのコンプレックスに対する抗体及びリガンド―レセプターアッセーでのそれらの用途 |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| WO1992018868A1 (en) | 1991-04-10 | 1992-10-29 | Biosite Diagnostics Incorporated | Crosstalk inhibitors and their uses |
| ATE195808T1 (de) | 1991-04-12 | 2000-09-15 | Biosite Diagnostics Inc | Neue konjugate und testverfahren für die gleichzeitige bestimmung von multiplen liganden |
| US6019944A (en) | 1992-05-21 | 2000-02-01 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| US6811773B1 (en) * | 1993-12-22 | 2004-11-02 | Human Genome Sciences, Inc. | Human monocyte colony inhibitory factor (M-CIF) polypeptides |
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| IL163547A0 (en) | 2002-02-12 | 2005-12-18 | Quark Biotech Inc | Use of the axl receptor for diagnosis and treatment of renal disease |
| US20120064089A1 (en) * | 2002-11-15 | 2012-03-15 | Morehouse School Of Medicine | Anti-cxcl16 and anti-cxcr6 antibodies for the prevention and treatment of cancer and cancer cell migration |
| US7833732B2 (en) | 2005-07-21 | 2010-11-16 | The John Hopkins University | Acute renal injury |
| AU2006292203A1 (en) * | 2005-09-21 | 2007-03-29 | Dask Technologies, Llc | Methods and compositions for organ and tissue functionality |
| WO2009038742A2 (en) | 2007-09-20 | 2009-03-26 | Caritas St. Elizabeth's Medical Center Of Boston, Inc. | Method for estimating risk of acute kidney injury |
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| NZ619918A (en) | 2008-10-21 | 2015-04-24 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011017685A1 (en) * | 2009-08-07 | 2011-02-10 | Rules-Based Medicine, Inc. | Methods and devices for detecting kidney transplant rejection |
| NZ630277A (en) * | 2009-09-21 | 2015-02-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2779905A1 (en) * | 2009-11-07 | 2011-05-12 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| MX340078B (es) * | 2009-11-07 | 2016-06-24 | Astute Medical Inc | Metodos y composiciones para el diagnostico y pronostico de daño renal y falla renal. |
| US20120156701A1 (en) * | 2009-12-20 | 2012-06-21 | Joseph Anderberg | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| KR20120123056A (ko) * | 2009-12-20 | 2012-11-07 | 아스튜트 메디컬 인코포레이티드 | 신손상 및 신부전을 진단 및 예측하는 방법 및 조성물 |
| EP2531620B1 (en) * | 2010-02-05 | 2016-12-14 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| AU2011269847A1 (en) * | 2010-02-26 | 2013-01-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2585827A4 (en) * | 2010-06-23 | 2013-12-04 | Astute Medical Inc | METHOD AND COMPOSITIONS FOR DIAGNOSIS AND FORECASTING kidney injury and kidney insufficiency |
| MX2013000220A (es) * | 2010-06-23 | 2013-03-22 | Astute Medical Inc | Metodos y composiciones para diagnóstico y pronóstico de lesión renal e insuficiencia renal. |
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| TR201903235T4 (tr) * | 2011-08-26 | 2019-03-21 | Astute Medical Inc | Böbrek hasari ve böbrek yetmezli̇ği̇ni̇n tanilanmasi ve prognozuna yöneli̇k metotlar ve bi̇leşi̇mler. |
| WO2013086359A1 (en) * | 2011-12-08 | 2013-06-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2013096740A1 (en) * | 2011-12-21 | 2013-06-27 | Alere San Diego Inc. | Methods and compositions for assigning likelihood of chronic kidney disease progression |
| EP2962109A4 (en) | 2013-02-26 | 2016-12-07 | Astute Medical Inc | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE |
| EP3968022A1 (en) | 2014-10-20 | 2022-03-16 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
-
2015
- 2015-10-20 EP EP21186630.6A patent/EP3968022A1/en active Pending
- 2015-10-20 JP JP2017521231A patent/JP6792553B2/ja active Active
- 2015-10-20 EA EA201790696A patent/EA201790696A1/ru unknown
- 2015-10-20 PT PT15853584T patent/PT3210018T/pt unknown
- 2015-10-20 KR KR1020177013539A patent/KR102431003B1/ko active Active
- 2015-10-20 CN CN201580068922.9A patent/CN107003301B/zh active Active
- 2015-10-20 CN CN201910986041.5A patent/CN110702921B/zh active Active
- 2015-10-20 EP EP15853584.9A patent/EP3210018B1/en active Active
- 2015-10-20 AU AU2015336069A patent/AU2015336069B2/en active Active
- 2015-10-20 MX MX2017005126A patent/MX388231B/es unknown
- 2015-10-20 ES ES15853584T patent/ES2907551T3/es active Active
- 2015-10-20 WO PCT/US2015/056462 patent/WO2016064877A2/en not_active Ceased
- 2015-10-20 US US15/520,817 patent/US11333671B2/en active Active
- 2015-10-20 CA CA2965153A patent/CA2965153C/en active Active
- 2015-10-20 BR BR112017008218A patent/BR112017008218A2/pt not_active Application Discontinuation
-
2020
- 2020-11-06 JP JP2020185705A patent/JP7002623B2/ja active Active
-
2021
- 2021-12-27 JP JP2021211779A patent/JP7217796B2/ja active Active
-
2022
- 2022-02-21 AU AU2022201130A patent/AU2022201130B2/en active Active
- 2022-03-31 US US17/710,832 patent/US12099067B2/en active Active
-
2023
- 2023-01-24 JP JP2023008480A patent/JP2023052587A/ja active Pending
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