TR201903235T4 - Böbrek hasari ve böbrek yetmezli̇ği̇ni̇n tanilanmasi ve prognozuna yöneli̇k metotlar ve bi̇leşi̇mler. - Google Patents
Böbrek hasari ve böbrek yetmezli̇ği̇ni̇n tanilanmasi ve prognozuna yöneli̇k metotlar ve bi̇leşi̇mler. Download PDFInfo
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- TR201903235T4 TR201903235T4 TR2019/03235T TR201903235T TR201903235T4 TR 201903235 T4 TR201903235 T4 TR 201903235T4 TR 2019/03235 T TR2019/03235 T TR 2019/03235T TR 201903235 T TR201903235 T TR 201903235T TR 201903235 T4 TR201903235 T4 TR 201903235T4
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- TR
- Turkey
- Prior art keywords
- kidney
- individual
- prognosis
- diagnosis
- compositions
- Prior art date
Links
- 210000003734 kidney Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 208000001647 Renal Insufficiency Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 201000006370 kidney failure Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000004393 prognosis Methods 0.000 title 1
- 102000000422 Matrix Metalloproteinase 3 Human genes 0.000 abstract 2
- 108010016160 Matrix Metalloproteinase 3 Proteins 0.000 abstract 2
- 102000019210 Metalloproteinase inhibitor 2 Human genes 0.000 abstract 2
- 108050006602 Metalloproteinase inhibitor 2 Proteins 0.000 abstract 2
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Pregnancy & Childbirth (AREA)
Abstract
Buluş, bir bireyde böbrek durumunu değerlendirmeye yönelik bir metot olup, bir test sonucu sağlamak üzere bireyden alınan bir vücut sıvısı örneğinde stromelisin-1:metalloproteinaz inhibitör 2 kompleksini saptamak üzere düzenlenen bir testin gerçekleştirilmesini; test sonucunun / sonuçlarının, bireyin böbrek durumu ile ilişkilendirilmesini içermekte, burada bahsedilen ilişkilendirme adımı, stromelisin-1:metalloproteinaz inhibitör 2 kompleksi konsantrasyonu formundaki bir test sonucunun, böbrek durumunda bir değişimin meydana gelmesi veya gelmemesinin göstergesi olarak veya böbrek durumunda bir veya daha fazla müstakbel değişimin olabilirliğinin göstergesi olarak seçilen önceden belirlenmiş bir eşik ile karşılaştırılmasını içermektedir.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161528000P | 2011-08-26 | 2011-08-26 | |
US201161528003P | 2011-08-26 | 2011-08-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201903235T4 true TR201903235T4 (tr) | 2019-03-21 |
Family
ID=47914751
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2019/03235T TR201903235T4 (tr) | 2011-08-26 | 2012-08-24 | Böbrek hasari ve böbrek yetmezli̇ği̇ni̇n tanilanmasi ve prognozuna yöneli̇k metotlar ve bi̇leşi̇mler. |
Country Status (16)
Country | Link |
---|---|
US (2) | US9459261B2 (tr) |
EP (2) | EP2748605B1 (tr) |
JP (2) | JP2014529073A (tr) |
KR (1) | KR20140074307A (tr) |
CN (2) | CN106443011A (tr) |
AU (1) | AU2012312907A1 (tr) |
BR (1) | BR112014004389A2 (tr) |
CA (1) | CA2846602A1 (tr) |
EA (1) | EA201490384A1 (tr) |
ES (1) | ES2721907T3 (tr) |
IN (1) | IN2014MN00377A (tr) |
MX (1) | MX346096B (tr) |
PL (1) | PL2748605T4 (tr) |
PT (1) | PT2748605T (tr) |
TR (1) | TR201903235T4 (tr) |
WO (1) | WO2013043310A1 (tr) |
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JP2012506537A (ja) | 2008-10-21 | 2012-03-15 | アスチュート メディカル,インコーポレイテッド | 腎損傷および腎不全の診断および予後のための方法および組成物 |
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EP3339860A1 (en) | 2010-06-23 | 2018-06-27 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
CA2846602A1 (en) * | 2011-08-26 | 2013-03-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
ES2933570T3 (es) | 2011-12-08 | 2023-02-10 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y el pronóstico de una lesión renal y de una insuficiencia renal |
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US11261257B2 (en) | 2013-01-28 | 2022-03-01 | Diasorin S.P.A. | Methods for detecting 1,25-dihydroxyvitamin D and related antibodies |
US10983136B2 (en) | 2013-01-28 | 2021-04-20 | Diasorin S.P.A. | Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker |
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BR112017008218A2 (pt) | 2014-10-20 | 2018-01-09 | Astute Medical Inc | métodos e composições para diagnóstico e prognóstico de lesão renal e insuficiência renal |
CA2973653A1 (en) * | 2015-01-18 | 2016-07-21 | Diasorin S.P.A. | Use of 1,25-dihydroxyvitamin d values in ratio with pth as a prognostic biomarker |
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-
2012
- 2012-08-24 CA CA2846602A patent/CA2846602A1/en not_active Abandoned
- 2012-08-24 MX MX2014002146A patent/MX346096B/es active IP Right Grant
- 2012-08-24 TR TR2019/03235T patent/TR201903235T4/tr unknown
- 2012-08-24 EP EP12832845.7A patent/EP2748605B1/en active Active
- 2012-08-24 IN IN377MUN2014 patent/IN2014MN00377A/en unknown
- 2012-08-24 JP JP2014527328A patent/JP2014529073A/ja active Pending
- 2012-08-24 CN CN201610804095.1A patent/CN106443011A/zh active Pending
- 2012-08-24 US US14/241,005 patent/US9459261B2/en active Active
- 2012-08-24 BR BR112014004389A patent/BR112014004389A2/pt not_active IP Right Cessation
- 2012-08-24 KR KR1020147007890A patent/KR20140074307A/ko not_active Application Discontinuation
- 2012-08-24 EA EA201490384A patent/EA201490384A1/ru unknown
- 2012-08-24 AU AU2012312907A patent/AU2012312907A1/en not_active Abandoned
- 2012-08-24 ES ES12832845T patent/ES2721907T3/es active Active
- 2012-08-24 PT PT12832845T patent/PT2748605T/pt unknown
- 2012-08-24 WO PCT/US2012/052298 patent/WO2013043310A1/en active Application Filing
- 2012-08-24 PL PL12832845T patent/PL2748605T4/pl unknown
- 2012-08-24 EP EP18209718.8A patent/EP3489690A1/en active Pending
- 2012-08-24 CN CN201280049909.5A patent/CN103874923B/zh active Active
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2016
- 2016-10-03 US US15/284,197 patent/US9784750B2/en active Active
- 2016-10-19 JP JP2016204848A patent/JP2017032586A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2014529073A (ja) | 2014-10-30 |
US20140213477A1 (en) | 2014-07-31 |
EP3489690A1 (en) | 2019-05-29 |
CA2846602A1 (en) | 2013-03-28 |
PT2748605T (pt) | 2019-05-03 |
ES2721907T3 (es) | 2019-08-06 |
PL2748605T3 (pl) | 2019-08-30 |
JP2017032586A (ja) | 2017-02-09 |
NZ621716A (en) | 2016-04-29 |
WO2013043310A1 (en) | 2013-03-28 |
US9459261B2 (en) | 2016-10-04 |
IN2014MN00377A (tr) | 2015-06-19 |
BR112014004389A2 (pt) | 2017-03-28 |
PL2748605T4 (pl) | 2019-08-30 |
KR20140074307A (ko) | 2014-06-17 |
US9784750B2 (en) | 2017-10-10 |
AU2012312907A1 (en) | 2014-03-13 |
MX2014002146A (es) | 2014-08-21 |
CN106443011A (zh) | 2017-02-22 |
CN103874923B (zh) | 2016-09-14 |
US20170016917A1 (en) | 2017-01-19 |
EP2748605A1 (en) | 2014-07-02 |
EP2748605A4 (en) | 2015-12-02 |
MX346096B (es) | 2017-03-07 |
CN103874923A (zh) | 2014-06-18 |
EA201490384A1 (ru) | 2014-08-29 |
EP2748605B1 (en) | 2018-12-05 |
NZ706242A (en) | 2016-07-29 |
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