MX385972B - Partículas y composiciones de nicotina. - Google Patents

Partículas y composiciones de nicotina.

Info

Publication number
MX385972B
MX385972B MX2018015118A MX2018015118A MX385972B MX 385972 B MX385972 B MX 385972B MX 2018015118 A MX2018015118 A MX 2018015118A MX 2018015118 A MX2018015118 A MX 2018015118A MX 385972 B MX385972 B MX 385972B
Authority
MX
Mexico
Prior art keywords
compositions
nicotine particles
particles
nicotine
sugar
Prior art date
Application number
MX2018015118A
Other languages
English (en)
Spanish (es)
Other versions
MX2018015118A (es
Inventor
Gerard Zuber
Nicolo Volpe
Original Assignee
Philip Morris Products Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa filed Critical Philip Morris Products Sa
Publication of MX2018015118A publication Critical patent/MX2018015118A/es
Publication of MX385972B publication Critical patent/MX385972B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1658Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
MX2018015118A 2016-06-30 2017-06-14 Partículas y composiciones de nicotina. MX385972B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16177163 2016-06-30
PCT/IB2017/053543 WO2018002756A1 (en) 2016-06-30 2017-06-14 Nicotine particles and compositions

Publications (2)

Publication Number Publication Date
MX2018015118A MX2018015118A (es) 2019-04-15
MX385972B true MX385972B (es) 2025-03-18

Family

ID=56296661

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018015118A MX385972B (es) 2016-06-30 2017-06-14 Partículas y composiciones de nicotina.

Country Status (19)

Country Link
US (2) US20190133940A1 (https=)
EP (1) EP3478264B1 (https=)
JP (2) JP2019524648A (https=)
KR (1) KR102523677B1 (https=)
CN (1) CN109310622A (https=)
AR (1) AR108920A1 (https=)
AU (1) AU2017286864A1 (https=)
CA (1) CA3023630A1 (https=)
ES (1) ES3055891T3 (https=)
IL (1) IL263355A (https=)
MX (1) MX385972B (https=)
PH (1) PH12018502714A1 (https=)
PL (1) PL3478264T3 (https=)
RU (1) RU2767064C2 (https=)
SG (1) SG11201809594WA (https=)
TW (1) TW201801716A (https=)
UA (1) UA124535C2 (https=)
WO (1) WO2018002756A1 (https=)
ZA (1) ZA201806949B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3055891T3 (en) * 2016-06-30 2026-02-16 Philip Morris Products Sa Nicotine particles and compositions
WO2020071448A1 (ja) * 2018-10-02 2020-04-09 学校法人名城大学 吸入粉末剤、その評価方法及びその用途
EP3946262B1 (en) * 2019-08-30 2024-07-31 Evie Sa Loaded granules, their process of production and their uses
CN110384700A (zh) * 2019-09-03 2019-10-29 云南喜科科技有限公司 一种合成尼古丁的组合物
UA130281C2 (uk) 2019-11-14 2026-01-07 Філіп Морріс Продактс С.А. Сухий порошковий склад зі смаком тютюну, спосіб його одержання та порошкова система
KR20220119101A (ko) 2019-12-19 2022-08-26 쥴 랩스, 인크. 유기 기반 니코틴 겔 조성물
EP4076026A1 (en) 2019-12-19 2022-10-26 Juul Labs, Inc. Metal oxide-based gel nicotine compositions
CA3164639A1 (en) 2019-12-20 2021-06-24 Juul Labs, Inc. Hydrated ionic clay and tobacco material compositions
WO2021201258A1 (ja) * 2020-04-01 2021-10-07 株式会社StateArt 核酸含有組成物、核酸含有組成物の製造方法及び核酸導入方法
ES3040112T3 (en) * 2020-06-15 2025-10-28 Philip Morris Products Sa Anatabine powder compositions
BR112023003114A2 (pt) * 2020-09-03 2023-04-04 Philip Morris Products Sa Composições em pó ativas de baixa higroscopicidade liofilizadas
WO2022049488A1 (en) * 2020-09-03 2022-03-10 Philip Morris Products S.A. Spray dried low hygroscopicity active powder compositions
US12594238B2 (en) * 2020-09-03 2026-04-07 Philip Morris Products S.A. Low hygroscopicity active powder compositions
USD1081739S1 (en) 2021-04-06 2025-07-01 Altria Client Services Llc Die for gum forming
US20220313678A1 (en) * 2021-04-06 2022-10-06 Altria Client Services Llc Spray dried nicotine for inclusion in oral products

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2231968A1 (en) * 1998-03-11 1999-09-11 Smoke-Stop, A Partnership Consisting Of Art Slutsky Method of producing a nicotine medicament
US6586008B1 (en) * 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
JP2001151673A (ja) * 1999-09-06 2001-06-05 Nikken Chem Co Ltd 吸入用粉末製剤の製造方法
NZ518401A (en) * 1999-10-29 2004-01-30 Nektar Therapeutics Dry powder compositions having improved dispersivity
SK11142002A3 (sk) * 1999-12-30 2004-09-08 Chiron Corporation Liečivo na podávanie interleukínu-2 a stabilizovaný lyofilizovaný alebo sprejovo sušený farmaceutický prostriedok s obsahom interleukínu-2
CA2418960A1 (en) * 2000-08-07 2002-02-14 Inhale Therapeutic Systems, Inc. Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
MX2007004495A (es) * 2004-10-15 2007-05-10 Pfizer Prod Inc Composiciones y procedimientos para la administracion intranasal, bucal, sublingual y pulmonar de vareniclina.
GB0425758D0 (en) * 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
ITMI20051999A1 (it) * 2005-10-21 2007-04-22 Eratech S R L Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
FI20060428A7 (fi) * 2006-05-03 2007-11-04 Esko Kauppinen Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia
US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
GB0801876D0 (en) * 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations
CA2944471C (en) * 2014-04-08 2020-03-31 Philip Morris Products S.A. Nicotine formulations and methods of making the same
CA2943746C (en) * 2014-04-28 2023-08-15 Philip Morris Products S.A. Flavoured nicotine powder inhaler
US10149844B2 (en) * 2015-09-16 2018-12-11 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
US9585835B1 (en) * 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
US11224594B2 (en) * 2015-09-16 2022-01-18 Philip Morris Products S.A. Nicotine formulations and methods of making and using the same
ES3055891T3 (en) * 2016-06-30 2026-02-16 Philip Morris Products Sa Nicotine particles and compositions
PL3478265T3 (pl) * 2016-06-30 2025-04-14 Philip Morris Products S.A. Cząstki nikotyny
IL269275B2 (en) * 2017-06-28 2023-04-01 Philip Morris Products Sa Container with particles for use with an inhaler

Also Published As

Publication number Publication date
AU2017286864A1 (en) 2018-11-15
IL263355A (en) 2018-12-31
ZA201806949B (en) 2019-07-31
JP2019524648A (ja) 2019-09-05
AR108920A1 (es) 2018-10-10
RU2018145313A (ru) 2020-07-30
EP3478264C0 (en) 2025-11-19
CA3023630A1 (en) 2018-01-04
MX2018015118A (es) 2019-04-15
RU2767064C2 (ru) 2022-03-16
EP3478264A1 (en) 2019-05-08
RU2021132299A (ru) 2021-12-10
ES3055891T3 (en) 2026-02-16
SG11201809594WA (en) 2018-11-29
TW201801716A (zh) 2018-01-16
KR102523677B1 (ko) 2023-04-20
US20210361567A1 (en) 2021-11-25
PH12018502714A1 (en) 2019-07-29
PL3478264T3 (pl) 2026-02-02
UA124535C2 (uk) 2021-10-05
JP2022071106A (ja) 2022-05-13
WO2018002756A1 (en) 2018-01-04
EP3478264B1 (en) 2025-11-19
US20190133940A1 (en) 2019-05-09
CN109310622A (zh) 2019-02-05
KR20190025824A (ko) 2019-03-12
RU2018145313A3 (https=) 2020-07-30
BR112018076215A2 (pt) 2019-03-26

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