MX376175B - Composiciones de grapiprant y metodos para usar las mismas. - Google Patents

Composiciones de grapiprant y metodos para usar las mismas.

Info

Publication number
MX376175B
MX376175B MX2016011025A MX2016011025A MX376175B MX 376175 B MX376175 B MX 376175B MX 2016011025 A MX2016011025 A MX 2016011025A MX 2016011025 A MX2016011025 A MX 2016011025A MX 376175 B MX376175 B MX 376175B
Authority
MX
Mexico
Prior art keywords
grapiprant
compositions
methods
same
human animal
Prior art date
Application number
MX2016011025A
Other languages
English (en)
Other versions
MX2016011025A (es
Inventor
Akemi Shiraishi
Gopinath Devaraj
Lesley Rausch-Derra
Tamara Newbold
Original Assignee
Aratana Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54016294&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX376175(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aratana Therapeutics Inc filed Critical Aratana Therapeutics Inc
Publication of MX2016011025A publication Critical patent/MX2016011025A/es
Publication of MX376175B publication Critical patent/MX376175B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente descripción proporciona un método para el tratamiento del dolor o la inflamación en un animal no humano con necesidad del mismo. El método comprende la administración a un animal no humano de una composición farmacéutica que comprende una cantidad terapéuticamente eficaz de grapiprant. También se proporcionan en la presente composiciones farmacéuticas para el tratamiento del dolor o la inflamación en un animal no humano con necesidad del mismo. Las composiciones farmacéuticas comprenden una cantidad terapéuticamente eficaz de grapiprant y un excipiente, incluyendo saborizantes.
MX2016011025A 2014-03-06 2015-03-05 Composiciones de grapiprant y metodos para usar las mismas. MX376175B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461948957P 2014-03-06 2014-03-06
US201462089713P 2014-12-09 2014-12-09
PCT/US2015/019037 WO2015134792A1 (en) 2014-03-06 2015-03-05 Compositions of grapiprant and methods for using the same

Publications (2)

Publication Number Publication Date
MX2016011025A MX2016011025A (es) 2016-11-29
MX376175B true MX376175B (es) 2025-03-07

Family

ID=54016294

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2016011025A MX376175B (es) 2014-03-06 2015-03-05 Composiciones de grapiprant y metodos para usar las mismas.
MX2020001428A MX2020001428A (es) 2014-03-06 2016-08-24 Composiciones de grapiprant y metodos para usar las mismas.
MX2022014763A MX2022014763A (es) 2014-03-06 2016-08-24 Composiciones de grapiprant y metodos para usar las mismas.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2020001428A MX2020001428A (es) 2014-03-06 2016-08-24 Composiciones de grapiprant y metodos para usar las mismas.
MX2022014763A MX2022014763A (es) 2014-03-06 2016-08-24 Composiciones de grapiprant y metodos para usar las mismas.

Country Status (15)

Country Link
US (3) US11369621B2 (es)
EP (1) EP3113774B1 (es)
JP (1) JP6419857B2 (es)
KR (1) KR102270323B1 (es)
CN (2) CN105939713A (es)
AU (1) AU2015227059B2 (es)
CA (1) CA2941008C (es)
DK (1) DK3113774T3 (es)
ES (1) ES2907285T3 (es)
MX (3) MX376175B (es)
PL (1) PL3113774T3 (es)
PT (1) PT3113774T (es)
RU (1) RU2679631C2 (es)
TW (2) TWI708606B (es)
WO (1) WO2015134792A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12109218B2 (en) * 2014-12-09 2024-10-08 Aratana Therapeutics, Inc. Compositions of grapiprant and methods for using the same
DK3113774T3 (da) * 2014-03-06 2022-03-07 Elanco Animal Health Incorporated Sammensætninger af grapiprant og fremgangsmåder til anvendelse deraf
EP3820480A4 (en) 2018-07-11 2022-03-09 Arrys Therapeutics, Inc. POLYMORPHIC COMPOUNDS AND USES THEREOF
EP3856177A4 (en) * 2018-09-27 2022-06-29 Arrys Therapeutics, Inc. Grapiprant unit dosage forms
CN115697317A (zh) * 2020-04-08 2023-02-03 株式会社AskAt Ep4受体拮抗剂用于治疗肝癌、黑色素瘤、淋巴瘤和白血病的应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DZ2479A1 (fr) 1997-05-05 2003-02-01 Pfizer Composés inhibiteurs sélectifs de cox-2 anti-inflammatoires et compositions pharmaceutiques les contenant.
JP2003506404A (ja) * 1999-08-10 2003-02-18 グラクソ グループ リミテッド 治療、とりわけ神経障害性疼痛および結腸癌の治療におけるｅｐ４受容体リガンドの使用
HN2001000224A (es) * 2000-10-19 2002-06-13 Pfizer Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos.
WO2003008637A2 (en) 2001-07-17 2003-01-30 Xanthus Life Sciences, Inc. Use of genotyping in the individualization of therapy
EP1450813B1 (en) * 2001-10-31 2007-08-29 Medical Research Council Antagonists of prostaglandin receptors ep2 and/or ep4 for the treatment of menorrhagia
MXPA04009243A (es) 2002-04-12 2005-06-08 Pfizer Uso de ligandos para el receptor ep4 en el tratamiento de enfermedades vinculadas a il-6.
WO2005102389A2 (en) 2004-04-20 2005-11-03 Pfizer Products Inc. Combinations comprising alpha-2-delta ligands and ep4 receptor antagonists
US7960407B2 (en) * 2005-03-11 2011-06-14 Requalia Pharma Inc. Crystal forms of an imidazole derivative
JP5244091B2 (ja) 2006-04-24 2013-07-24 メルク カナダ インコーポレイテッド Ｅｐ４受容体アンタゴニストとしてのインドールアミド誘導体
US20080242713A1 (en) * 2007-03-28 2008-10-02 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives as agents for the treatment of autoimmune diseases
MX341482B (es) 2010-02-22 2016-08-22 Raqualia Pharma Inc Antagonistas del receptor ep4 y su uso en el tratamiento de enfermedades mediadas por la il-23.
WO2011124525A1 (de) * 2010-04-08 2011-10-13 Boehringer Ingelheim International Gmbh Arnzeimittelkombinationen enthaltend pde4-inhibitoren und ep4-rezeptor-antagonisten
EP2627318B1 (en) 2010-10-12 2017-08-16 Merz Pharma GmbH & Co. KGaA Formulation suitable for stabilizing proteins, which is free of mammalian excipients
MX2013010306A (es) * 2011-03-08 2013-12-09 Zalicus Pharmaceuticals Ltd Formulaciones de dispersion solida y metodos de uso de las mismas.
US9187463B2 (en) 2011-05-18 2015-11-17 Raqualia Pharma Inc. Polymorph form of 4-{[4-({[4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazol-3-yl]oxy}methyl)piperidin-1-yl]methyl}-tetrahydro-2H-pyran-4-carboxylic acid
ITBO20110461A1 (it) * 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
CN107496421A (zh) 2013-03-19 2017-12-22 株式会社ＡｓｋＡｔ Ep4受体拮抗剂在软骨疾病的治疗中的用途
CN107400132A (zh) 2014-03-06 2017-11-28 阿莱塔纳治疗学股份有限公司 Grapiprant的结晶形式
US12109218B2 (en) * 2014-12-09 2024-10-08 Aratana Therapeutics, Inc. Compositions of grapiprant and methods for using the same
DK3113774T3 (da) * 2014-03-06 2022-03-07 Elanco Animal Health Incorporated Sammensætninger af grapiprant og fremgangsmåder til anvendelse deraf

Also Published As

Publication number Publication date
KR20160129887A (ko) 2016-11-09
WO2015134792A1 (en) 2015-09-11
US11369621B2 (en) 2022-06-28
RU2016137926A (ru) 2018-04-09
US20150250773A1 (en) 2015-09-10
AU2015227059A1 (en) 2016-09-22
RU2019102384A3 (es) 2022-03-31
EP3113774A4 (en) 2017-10-25
EP3113774A1 (en) 2017-01-11
CA2941008A1 (en) 2015-09-11
TWI708606B (zh) 2020-11-01
ES2907285T3 (es) 2022-04-22
MX2020001428A (es) 2020-03-20
JP6419857B2 (ja) 2018-11-07
RU2019102384A (ru) 2019-03-04
TW201603812A (zh) 2016-02-01
MX2022014763A (es) 2023-01-11
CN105939713A (zh) 2016-09-14
RU2679631C2 (ru) 2019-02-12
KR102270323B1 (ko) 2021-06-29
TW201815393A (zh) 2018-05-01
TWI664969B (zh) 2019-07-11
NZ761827A (en) 2021-03-26
US20160317559A1 (en) 2016-11-03
AU2015227059B2 (en) 2018-11-15
CN112370450A (zh) 2021-02-19
CA2941008C (en) 2022-07-26
DK3113774T3 (da) 2022-03-07
US12478633B2 (en) 2025-11-25
JP2017507190A (ja) 2017-03-16
MX2016011025A (es) 2016-11-29
NZ724007A (en) 2021-02-26
PL3113774T3 (pl) 2022-06-13
PT3113774T (pt) 2022-02-28
EP3113774B1 (en) 2022-01-26
US20250025481A1 (en) 2025-01-23

Similar Documents

Publication Publication Date Title
ZA202308495B (en) Pharmaceutical compositions of therapeutically active compounds
CO2019006291A2 (es) Composiciones de aminoácidos y métodos de tratamiento de enfermedades hepáticas
MX2018006578A (es) Formulaciones farmaceuticas topicas para tratar afecciones inflamatorias.
EA201790398A1 (ru) Способы лечения заболевания печени
NI201600051A (es) Combinaciones de inhibidores de histona desacetilasa y farmacos inmunomoduladores
NI201600071A (es) Compuestos de inhibidor de autotaxina
MX2015009058A (es) Composiciones y metodos para tratar la inflamacion cronica y las enfermedades inflamatorias.
EA202090098A1 (ru) Фармацевтические композиции терапевтически активных соединений
EA201690039A1 (ru) Ингибиторы rorc2 и способы их применения
MX2015009045A (es) Composiciones y metodos para tratar el dolor severo.
NI201600070A (es) Inhibidores tetracíclicos de autotaxina
MX394452B (es) Inhibicion de la actividad de olig2.
EA201591507A1 (ru) Лечение рассеянного склероза лахинимодом
MX2018012230A (es) Métodos para tratar enfermedades oculares.
MX2017005064A (es) Metodos para tratar afecciones oculares.
MX376175B (es) Composiciones de grapiprant y metodos para usar las mismas.
PH12016500910A1 (en) Long-acting ketoprofen compositions
MX394015B (es) Inhibición de la actividad de la olig2.
PL3458068T3 (pl) Kompozycja do stosowania miejscowego do leczenia bólu u zwierząt
EA202190626A2 (ru) Комбинация тразодона и габапентина для лечения боли
AR130700A2 (es) Composiciones de grapiprant y métodos para su utilización
AR099681A1 (es) Composiciones de grapiprant y métodos para su utilización
ZA201606135B (en) Pharmaceutical compositions of therapeutically active compounds
IN2013MU03429A (es)
UA106472U (uk) Засіб для лікування дерматологічних захворювань

Legal Events

Date Code Title Description
FG Grant or registration