MX370081B - Procedimiento para la preparacion de complejos de 68ga. - Google Patents

Procedimiento para la preparacion de complejos de 68ga.

Info

Publication number
MX370081B
MX370081B MX2014001691A MX2014001691A MX370081B MX 370081 B MX370081 B MX 370081B MX 2014001691 A MX2014001691 A MX 2014001691A MX 2014001691 A MX2014001691 A MX 2014001691A MX 370081 B MX370081 B MX 370081B
Authority
MX
Mexico
Prior art keywords
preparation
complexes
formate
formic acid
metal cations
Prior art date
Application number
MX2014001691A
Other languages
English (en)
Spanish (es)
Other versions
MX2014001691A (es
Inventor
Lorenza Fugazza
Maria Azzurra Filannino
Maurizio Franco Mariani
Original Assignee
Advanced Accelerator Applications Int S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Accelerator Applications Int S A filed Critical Advanced Accelerator Applications Int S A
Publication of MX2014001691A publication Critical patent/MX2014001691A/es
Publication of MX370081B publication Critical patent/MX370081B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2014001691A 2011-08-12 2012-08-10 Procedimiento para la preparacion de complejos de 68ga. MX370081B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000180A ITFI20110180A1 (it) 2011-08-12 2011-08-12 Processo per la preparazione di complessi di 68ga.
PCT/EP2012/065659 WO2013024013A2 (en) 2011-08-12 2012-08-10 Process for the preparation of complexes of 68ga.

Publications (2)

Publication Number Publication Date
MX2014001691A MX2014001691A (es) 2014-11-13
MX370081B true MX370081B (es) 2019-11-29

Family

ID=44898621

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014001691A MX370081B (es) 2011-08-12 2012-08-10 Procedimiento para la preparacion de complejos de 68ga.

Country Status (19)

Country Link
US (2) US9375498B2 (enExample)
EP (3) EP2742017B1 (enExample)
JP (1) JP6161610B2 (enExample)
CN (1) CN103889930B (enExample)
AU (1) AU2012297008B2 (enExample)
BR (2) BR112014003336B1 (enExample)
CA (2) CA2844145C (enExample)
CO (1) CO7020857A2 (enExample)
DK (1) DK2742017T3 (enExample)
ES (2) ES2835581T3 (enExample)
IL (3) IL230904B (enExample)
IN (1) IN2014CN01897A (enExample)
IT (1) ITFI20110180A1 (enExample)
MX (1) MX370081B (enExample)
PL (1) PL2742017T3 (enExample)
PT (1) PT2742017E (enExample)
RU (2) RU2605090C2 (enExample)
WO (1) WO2013024013A2 (enExample)
ZA (1) ZA201401789B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1021191B1 (fr) 2014-08-29 2015-10-27 Anmi S.A. Kit pour radiomarquage.
US11027030B2 (en) 2014-08-29 2021-06-08 Anmi S.A. Kit for radiolabelling
MX373709B (es) * 2015-01-30 2020-05-08 Advanced Accelerator Applications Int S A Proceso para la purificacion de ga-68 a partir del eluato que se deriva de generadores de 68ge/ 68ga y columnas cromatograficas para usarse en dicho proceso.
IL237525A (en) 2015-03-03 2017-05-29 Shalom Eli Method for labeling a prostate-specific membrane antigen with a radioactive isotope
GB201504064D0 (en) * 2015-03-10 2015-04-22 Accretion Biotechnology Ltd Method and kits for preparing radionuclide complexes
IL297323A (en) * 2020-04-29 2022-12-01 Novartis Ag Methods for radiological labeling of psma-binding ligands and their kits
RU2760273C1 (ru) * 2020-11-02 2021-11-23 Федеральное государственное бюджетное учреждение науки Ордена Трудового Красного Знамени Институт химии силикатов им. И.В. Гребенщикова Российской академии наук (ИХС РАН) Способ получения комплексов на основе изотопа галлий-68
CA3217589A1 (en) 2021-05-31 2022-12-08 Frederik Giesel Improved prostate-specific membrane antigen targeting radiopharmaceuticals and uses thereof
FR3130840B1 (fr) * 2021-12-16 2023-11-03 Univ Bordeaux Procédé de séquestration de méthionine contenue dans un liquide et matériau convenant à la mise en œuvre d’un tel procédé

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6056939A (en) * 1998-08-28 2000-05-02 Desreux; Jean F. Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals
WO2003048207A2 (en) * 2001-11-28 2003-06-12 Immunomedics, Inc. Anti-dota antibody
GB0308408D0 (en) * 2003-04-11 2003-05-21 Amersham Plc Microwave activation
CN100418585C (zh) * 2003-07-24 2008-09-17 伯拉考成像股份公司 稳定的放射性药物组合物及制备方法
CN1874792A (zh) 2003-09-03 2006-12-06 布里斯托尔-迈尔斯.斯奎布制药公司 包含基质金属蛋白酶底物的化合物及其使用方法
DE102004057225B4 (de) * 2004-11-26 2006-10-12 Johannes-Gutenberg-Universität Mainz Verfahren und Vorrichtung zur Isolierung eines chemisch und radiochemisch gereinigten 68Ga-Radionuklids und zum Markieren eines Markierungsvorläufers mit dem 68Ga-Radionuklid
CN101528270A (zh) * 2006-08-28 2009-09-09 通用电气健康护理有限公司 基于68Ga标记的肽的放射性药物
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
WO2010141833A2 (en) * 2009-06-05 2010-12-09 The General Hospital Corporation Vital fluorochrome conjugates and methods of use

Also Published As

Publication number Publication date
WO2013024013A2 (en) 2013-02-21
RU2016144237A3 (enExample) 2019-10-10
US9907868B2 (en) 2018-03-06
NZ622071A (en) 2015-07-31
DK2742017T3 (da) 2016-02-08
CA2844145C (en) 2019-07-30
IL230904A0 (en) 2014-03-31
AU2012297008A1 (en) 2014-03-20
IL245849B (en) 2021-03-25
EP2955168B1 (en) 2020-09-23
BR112014003336A2 (pt) 2017-03-14
JP2014524423A (ja) 2014-09-22
US20140171637A1 (en) 2014-06-19
IL275979A (en) 2020-08-31
PL2742017T3 (pl) 2016-04-29
IL245849A0 (en) 2016-07-31
EP2742017B1 (en) 2015-10-28
IN2014CN01897A (enExample) 2015-05-29
ES2835581T3 (es) 2021-06-22
NZ708281A (en) 2016-01-29
CO7020857A2 (es) 2014-08-11
MX2014001691A (es) 2014-11-13
RU2605090C2 (ru) 2016-12-20
CA3045484A1 (en) 2013-02-21
RU2016144237A (ru) 2018-12-18
EP3718991A1 (en) 2020-10-07
RU2014109381A (ru) 2015-09-20
US9375498B2 (en) 2016-06-28
IL275979B2 (en) 2023-02-01
CN103889930B (zh) 2017-03-29
ZA201401789B (en) 2015-01-28
IL275979B (en) 2022-10-01
US20160263259A1 (en) 2016-09-15
ES2560231T3 (es) 2016-02-18
RU2020120802A (ru) 2021-12-23
ITFI20110180A1 (it) 2013-02-13
AU2012297008B2 (en) 2016-12-08
CA3045484C (en) 2022-10-11
BR122020011908B1 (pt) 2022-07-05
JP6161610B2 (ja) 2017-07-12
EP2955168A1 (en) 2015-12-16
CN103889930A (zh) 2014-06-25
IL230904B (en) 2019-01-31
CA2844145A1 (en) 2013-02-21
EP2742017A2 (en) 2014-06-18
WO2013024013A3 (en) 2013-05-02
PT2742017E (pt) 2016-02-26
BR112014003336B1 (pt) 2021-03-09

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Legal Events

Date Code Title Description
GB Transfer or rights

Owner name: ADVANCED ACCELERATOR APPLICATIONS INTERNATIONAL S.A.

FG Grant or registration